MAR 14, 2018 1:00 PM PDT

"Psychoactive" Semantics of Cannabinoids

WRITTEN BY: Mauri Brueggeman

I recently read an article which I got me thinking about the terminology we use in medicine versus everyday language.  There are certain terms used to commonly describe the activity of medicinal marijuana and its related cannabinoids and terpenes.  While the concept is not new for neuroscientists and others in the field of medicine, the discussion has not affected much change.  The language of medicine is considered by many to be like other foreign languages; the vocabulary is formed from Greek and Latin word parts, eponyms, acronyms, and modern language combined.  It is also built to be devoid of subjective interpretation.  The focus is on precise word choice which is used to provide consistent meaning regardless of who is reading the information/word choices.

The word “psychoactive” uses the medical combining form ‘psych/o’ = mind, and the modern word ‘active’ = engaged in or causing activity or change/capable of exerting influence.  The term “psychoactive” is commonly used with regard to cannabis compounds and their physiological effects.  Most articles, from peer-reviewed to blog, link tetrahydrocannabinol, or THC, with this word; alternatively, writers add a prefix that implies negation or absence regarding other cannabinoids.  The most common example is to say, “Of the cannabinoids found in marijuana, THC is the psychoactive component and cannabidiol is a non-psychoactive component”

What is this really saying?  The term “psychoactive” is defined by medical dictionaries and neuroscientists as “affecting the mind and behavior” as provided above in the medical terminology reminder.  This strict definition is called a denotation.  Medical language relies on denotation for accuracy and uniformity.

Dr. Adie Poe, neuroscientist with Washington University in St. Louis, has said, “…any substance that exerts its effects by directly impacting brain activity is considered to be psychoactive”.  Dr. Ethan Russo, a neurologist and psychopharmacology researcher, has written about the myths surrounding cannabis and indicated that “CBD is frequently mischaracterized in comparison to THC…” Dr. Russo is referring to the fact that CBD has been proven to have a positive effect on the mind and behavior in numerous medical conditions including anxiety, neuropathies, schizophrenia, addiction, and others.  So, CBD is psychoactive but in a beneficial, helpful, non-mind-altering way.   More accurate descriptors for CBD have been suggested to include words like non-intoxicating or non-impairing. 

Another tool to discern meaning, in addition to denotation, is connotation. The term "psychoactive" has come to have a negative connotation which says something about its use and application in society; the term marijuana for many is synonymous with the ugly side of drugs, dangerous addiction, legality concerns, and negative effects on one’s mental state (ie. links to paranoia, hallucinations, disorganized thinking, mental health problems, etc.). There is an emotional and psychological aspect to language and word choice that affects societal views and the ability to successfully convey meaning.  The connotation of words goes beyond denotation to evoke feelings, thoughts, and images that affect an individual’s interpretation of that word or descriptor.

There are many cannabis compounds to learn about and vast areas of research to be done to truly help patients; work continues to identify the appropriate positive outcomes and associated negatives or risk factors to align and develop therapeutic plans for patients, diseases, and conditions.  The least we can do, myself included, is get some of the words right to be accurate and not add to the potential mischaracterization of this plant’s potential.   

Sources: Cannabis Clinicians, Trends in Pharmacological SciencesProf of Pot, Habu Health

About the Author
  • Mauri S. Brueggeman is a Medical Laboratory Scientist and Educator with a background in Cytogenetics and a Masters in Education from the University of Minnesota. She has worked in the clinical laboratory, taught at the University of Minnesota, and been in post secondary healthcare education administration. She is passionate about advances and leadership in science, medicine, and education.
You May Also Like
OCT 29, 2020
Cannabis Sciences
Hemp 10 Years from Now
OCT 29, 2020
Hemp 10 Years from Now
The hemp industry has experienced major growth in recent years, largely due to legalization in many US states. Today, th ...
DEC 01, 2020
Cannabis Sciences
CBD Does Not Effect Driving Ability, THC Wears Off in 4 Hours
DEC 01, 2020
CBD Does Not Effect Driving Ability, THC Wears Off in 4 Hours
Researchers from the Lambert Initiative at the University of Sydney, have found that cannabidiol, a medically active com ...
JAN 14, 2021
Health & Medicine
Cannabis Use May Affect Pregnancy Chances
JAN 14, 2021
Cannabis Use May Affect Pregnancy Chances
Some people find that pot can give their sex life a boost. But if you’re planning opt make a baby using cannabis m ...
FEB 06, 2021
Cannabis Sciences
Cannabis Reduces Disruptive Behavior in 50% of Young People with Autism
FEB 06, 2021
Cannabis Reduces Disruptive Behavior in 50% of Young People with Autism
Current pharmacotherapies for disruptive behaviors among those with autism are relatively ineffective. Now though, resea ...
APR 01, 2021
Health & Medicine
Safety and Contamination Concerns Over Hemp Products
APR 01, 2021
Safety and Contamination Concerns Over Hemp Products
  When the 2018 Farm Bill legalized the regulated production of low-THC hemp, as distinct from other cannabis plant ...
APR 12, 2021
Health & Medicine
Chronic Pain Patients Can Find Long-Term Success Using Cannabis
APR 12, 2021
Chronic Pain Patients Can Find Long-Term Success Using Cannabis
Many users report immediate pain relief from using medical cannabis, but now a recently published study suggests chronic ...
Loading Comments...