APR 29, 2016 12:26 PM PDT

Sedentary Lifestyles Boost Coronary Artery Calcification

WRITTEN BY: Kara Marker
The development of dangerous coronary artery calcification shares a common pathway with bone formation, and so heart conditions relating to calcification can also have repercussions involving risk factors for bone disease.
New findings from UT Southwestern Medical Center’s Dallas Heart Study have implicated a largely sedentary lifestyle with increased amounts of calcium deposits in heart arteries, commonly called coronary artery calcification. As calcification levels rise, so does the risk for heart attack.
Cholesterol builds up in heart arteries at increasing rate depending on a person’s diet and exercise choices. Cholesterol clumps together in plaques, and calcium accumulate in the clumps. Coronary artery calcification can be measured with a CT scan as a representation of a patient’s heart attack risk and cholesterol plaque levels.
An example of how calcification clogs arteries and inhibits blood and oxygen flow
“Efforts to control coronary artery calcification with medical therapy has not been successful,” said a report in the Journal of the American College of Cardiology. Percutaneous coronary intervention and bypass graft surgery seem to help increase the length of “event-free” survival in heart disease patients with coronary artery calcification, but prevention is the only true tool to fight back against this condition.
The study involved over two thousand participants wearing devices that measured their physical activity for one week. On average, participants spend 5.1 hours per day sitting and 29 minutes per day participating in light to intense physical activity. What researchers are calling “excessive sitting” is incredibly dangerous for human heart health, even for the participants on the more active end of the exercise spectrum.
Senor author Dr. Amit Khera said the direct relationship between sedentary/sitting time and coronary artery calcification is independent of exercise, socioeconomic factors, and “traditional cardiovascular disease risk factors such as diabetes and high blood pressure.”
“Subclinical atherosclerosis characterized by calcium deposition is one of the mechanisms through which sedentary behavior increases cardiovascular risk and that this risk is distinct from the protective power of exercise,” explained Khera.
In addition to maintaining a healthy, regular exercise regimen, researchers are recommending a reduction of daily sitting time by just one or two hours to make a large difference in heart health.
“Each additional hour of daily sedentary time is associated with a 12 percent higher likelihood of coronary artery calcification,” said Khera.
The present study is published in the Journal of the American College of Cardiology: Cardiovascular Imaging.
Sources: UT Southwestern Medical Center, Journal of the American College of Cardiology
About the Author
  • I am a scientific journalist and enthusiast, especially in the realm of biomedicine. I am passionate about conveying the truth in scientific phenomena and subsequently improving health and public awareness. Sometimes scientific research needs a translator to effectively communicate the scientific jargon present in significant findings. I plan to be that translating communicator, and I hope to decrease the spread of misrepresented scientific phenomena! Check out my science blog: ScienceKara.com.
You May Also Like
FEB 05, 2020
Cell & Molecular Biology
FEB 05, 2020
Gut Bacteria Affect How the Colon Moves
The contraction and relaxation of muscles in the wall of the colon helps move food along and can become dysfunctional....
FEB 13, 2020
FEB 13, 2020
Protein that suppresses immune system linked to lupus
  A study published in Human Immunology has described, for the first time, a link between an immunosuppressive protein on the surface of T cells and t...
FEB 14, 2020
FEB 14, 2020
Rewired natural killer cells show promising results in leukemia patients
Natural killer (NK) cells are a subset of white blood cells that are key players in the innate immune system, orchestrating host-rejection responses agains...
FEB 12, 2020
Drug Discovery & Development
FEB 12, 2020
Does Traditional Chinese Medicine Work Against Coronavirus?
Over 45,000 cases of Wuhan Coronavirus have been reported globally, alongside over 1,100 deaths. Although over 4,700 people are said to have recovered from...
FEB 12, 2020
FEB 12, 2020
Using Genomics to Learn More About a Mumps Outbreak
Though vaccination rates are high, small mumps outbreaks sometimes still occur....
FEB 12, 2020
FEB 12, 2020
Can we eradicate cervical cancer within a century?
Two studies recently published in The Lancet present evidence that the eradication of cervical cancer could be possible within the next century. The World ...
Loading Comments...