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JAN 10 - 13 2022

Bionano Genomics 2022 Symposium

Event doors will open at 7:30am PT, 10:30am ET.  Event begins at 8:00am PT, 11:00am ET

Bionano Genomics is transforming the way the world sees the genome. As a leading provider of genomic analysis solutions, we enable researchers and clinicians to reveal answers to challenging genomic questions. By detecting structural variants using optical genome mapping (OGM), researchers are able to answer genomic questions that were previously unanswered.

Event Highlights:

At the Bionano Genomics 2022 Symposium, you will hear from over 25 customers around the world who will showcase their findings and answers using OGM. Each day will feature customer presentations, a live panel with Q&A, as well as poster presentations by topic area.

Topics include:

Monday, January 10: Constitutional Cytogenomics

Tuesday, January 11: Hematologic Malignancies

Wednesday, January 12: Solid Tumors

Thursday, January 13: OGM + NGS

Even though each day is topic specific, we encourage you to attend all days and sessions that interest you. All presentations will be recorded and available on demand after the symposium concludes.


Speakers
  • Chaim Jalas

    Chief Operations Officer and Director of Technology Development, Foundation for Embryonic Competence
    BIOGRAPHY
  • Laïla El Khattabi, PharmaD, PhD

    Associate Professor Genomic Technologies & Immuno-Genomics, APHP - Université de Paris
    BIOGRAPHY
  • Shirley Heggarty, BSc., PhD, FRC Path Molecular Genetics

    Consultant Clinical Scientist - Belfast Health and Social Care Trust
    BIOGRAPHY
  • Alexander Hoischen, PhD

    Associate Professor Genomic Technologies & Immuno-Genomics - Radboud University Medical Center, Nijmegen, The Netherlands
    BIOGRAPHY
  • M Anwar Iqbal, PhD, FFACMGG

    Professor and Director, DNA microarrayCGH Laboratory - University of Rochester Medical Center
    BIOGRAPHY
  • Nikhil S. Sahajpal, PhD.

    Post-doctoral Fellow, Augusta University
    BIOGRAPHY
  • Bence Dvoràk, MSc. Biomedical Sciences

    Oncology Lab - University Children's Hospital Zurich - Eleonore Foundation
    BIOGRAPHY
  • Jonathan L. Lühmann, MSc

    PhD Student - Molecular Medicine at the Hannover Medical School, Germany
    BIOGRAPHY
  • Anna Puiggros, PhD

    Assistant Biologist, Hospital del Mar - Barcelona
    BIOGRAPHY
  • Ir. Barbara Dewaele, PhD

    Laboratory Geneticist - University Hospitals Leuven
    BIOGRAPHY
  • Elena García Sánchez, PhD

    Post-doctoral Researcher - FIB Hospital Infantil Universitario Niño Jesús
    BIOGRAPHY
  • Kornelia Neveling, PhD

    Scientific Researcher Translational Genomics, Radboud - University Medical Center, Nijmegen, The Netherlands
    BIOGRAPHY
  • Brynn Levy, M.Sc.(Med)., Ph.D., FACMG

    Professor of Pathology & Cell Biology at CUMC - Columbia University Medical Center
    BIOGRAPHY
  • Adrian Dubuc, PhD, FACMG

    Associate Professor and Director (Microarray), Hematopathology and Molecular Diagnostics Laboratory
    BIOGRAPHY
  • Adam C. Smith, MSc, PhD, FCCMG, FACMG, erCLG

    Director, Cancer Cytogenetics Laboratory - Laboratory Medicine Program University Health Network - Toronto
    BIOGRAPHY
  • Saurabh Gupta, Ph.D., DABMGG

    Chief Director, Quest Diagnostics
    BIOGRAPHY
  • Tuomo Mantere

    Cancer and Translational Medicine Research Unit and Biocenter Oulu, University of Oulu, Finland
    BIOGRAPHY
  • Gopalrao Velagaleti, PhD

    Professor and Director - Department of Pathology and Laboratory Medicine, UT Health - San Antonio
    BIOGRAPHY
  • Miriam Bornhorst, MD

    Clinical Director Gilbert Family Neurofibromatosis Institute, Medical Director Cancer Genetics Program - Children's National Hospital
    BIOGRAPHY
  • Matthew Brian Couger, PhD

    Lead Investigator - Brigham and Women's Hospital
    BIOGRAPHY
  • Juan Diaz-Martin, PhD

    Research Associate - IBiS-HUVR
    BIOGRAPHY
  • Ravindra Kolhe, MD, PhD

    Associate Dean for Translational Research; Associate Director for Genomics, Georgia Cancer Center; Leon Henri Charbonnier Endowed Chair of Pathology, Medical College of Georgia
    BIOGRAPHY
  • Mariangela Sabatella, PhD

    Postdoctoral Fellow
    BIOGRAPHY
  • Gordana Raca, MD

    Director of the Cytogenomics Laboratory in the Center for Personalized Medicine in the Department of Pathology and Laboratory Medicine at Children's Hospital Los Angeles
    BIOGRAPHY
  • Arran Constantine, BSc Biochemistry

    Scientist - Bit.bio
    BIOGRAPHY
  • Saumyaa Saumyaa

    Senior Scientist - AstraZeneca
    BIOGRAPHY
  • Jens Luebeck, PhD

    Postdoctoral Researcher - University of California, San Diego
    BIOGRAPHY
  • Rashmi Kanagal-Shamanna, MD

    Associate Professor and Director (Microarray), Hematopathology and Molecular Diagnostics Laboratory, MD Anderson Cancer Center
    BIOGRAPHY

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Agenda

  • A Comprehensive Assessment of a Large Myelodysplastic Syndrome Cohort at MD Anderson Cancer Center Using Optical Genome Mapping and a Targeted NGS Panel
    JAN 13, 2022 11:10 AM PST

    A Comprehensive Assessment of a Large Myelodysplastic Syndrome Cohort at MD Anderson Cancer Center Using Optical Genome Mapping and a Targeted NGS Panel

    Rashmi Kanagal-Shamanna, MD
    Associate Professor and Director (Microarray), Hematopathology and Molecular Diagnostics Laboratory, MD Anderson Cancer Center
    BIOGRAPHY
  • Clinical Utility of Combined Optical Genome Mapping and Comprehensive Genomic Sequencing in Robust Evaluation of Hematological Cancers
    JAN 13, 2022 10:40 AM PST

    Clinical Utility of Combined Optical Genome Mapping and Comprehensive Genomic Sequencing in Robust Evaluation of Hematological Cancers

    Ravindra Kolhe, MD, PhD
    Associate Dean for Translational Research; Associate Director for Genomics, Georgia Cancer Center; Leon Henri Charbonnier Endowed Chair of Pathology, Medical College of Georgia
    BIOGRAPHY
  • Combined NGS and Optical Genome Mapping Reveal the Complex Structures of Circular Extrachromosomal DNA and other Focal Amplifications in Cancer Genomes
    JAN 13, 2022 10:25 AM PST

    Combined NGS and Optical Genome Mapping Reveal the Complex Structures of Circular Extrachromosomal DNA and other Focal Amplifications in Cancer Genomes

    Jens Luebeck, PhD
    Postdoctoral Researcher - University of California, San Diego
    BIOGRAPHY
  • Molecular Characterization of Genome Structural Variants in Developmental Disorders: Comparison Between Optical Genome Mapping and Short Read Whole Genome Sequencing
    JAN 13, 2022 10:00 AM PST

    Molecular Characterization of Genome Structural Variants in Developmental Disorders: Comparison Between Optical Genome Mapping and Short Read Whole Genome Sequencing

    Laïla El Khattabi, PharmaD, PhD
    Associate Professor Genomic Technologies & Immuno-Genomics, APHP - Université de Paris
    BIOGRAPHY
  • Detection and Characterization of On- and Off-target Integration of Foreign DNA in the Host Genomes, for Therapeutic Cell and Gene Therapy Development, Using Novel Optical DNA Mapping Tech
    JAN 13, 2022 9:35 AM PST

    Detection and Characterization of On- and Off-target Integration of Foreign DNA in the Host Genomes, for Therapeutic Cell and Gene Therapy Development, Using Novel Optical DNA Mapping Tech

    Saumyaa Saumyaa
    Senior Scientist - AstraZeneca
    BIOGRAPHY
  • Cytogenetic QC at bit.bio: How a Next-Generation Cytogentics Platform Enhances Quality Control of Next-Generation Cells
    JAN 13, 2022 9:30 AM PST

    Cytogenetic QC at bit.bio: How a Next-Generation Cytogentics Platform Enhances Quality Control of Next-Generation Cells

    Arran Constantine, BSc Biochemistry
    Scientist - Bit.bio
    BIOGRAPHY
  • OGM and Capture-Based RNA-Seq Enable Comprehensive Genomic Characterization of Pediatric B-lymphoblastic Leukemias
    JAN 13, 2022 9:00 AM PST

    OGM and Capture-Based RNA-Seq Enable Comprehensive Genomic Characterization of Pediatric B-lymphoblastic Leukemias

    Gordana Raca, MD
    Director of the Cytogenomics Laboratory in the Center for Personalized Medicine in the Department of Pathology and Laboratory Medicine at Children's Hospital Los Angeles
    BIOGRAPHY
  • Enlightening the Dark Matter of the Genome: Optical Genome Mapping Identifies a Germline Retrotransposon Insertion in SMARCB1 in Two Siblings with Atypical Teratoid Rhabdoid Tumors
    JAN 13, 2022 8:40 AM PST

    Enlightening the Dark Matter of the Genome: Optical Genome Mapping Identifies a Germline Retrotransposon Insertion in SMARCB1 in Two Siblings with Atypical Teratoid Rhabdoid Tumors

    Mariangela Sabatella, PhD
    Postdoctoral Fellow
    BIOGRAPHY
  • Optical Genome Mapping: Different Types of Hidden SV's in Families with Inherited Retinal Diseases
    JAN 13, 2022 8:20 AM PST

    Optical Genome Mapping: Different Types of Hidden SV's in Families with Inherited Retinal Diseases

    Kornelia Neveling, PhD
    Scientific Researcher Translational Genomics, Radboud - University Medical Center, Nijmegen, The Netherlands
    BIOGRAPHY
  • Utility Of Optical Genome Mapping for the Chromosomal Characterization of Solid Tumors
    JAN 12, 2022 10:15 AM PST

    Utility Of Optical Genome Mapping for the Chromosomal Characterization of Solid Tumors

    Ravindra Kolhe, MD, PhD
    Associate Dean for Translational Research; Associate Director for Genomics, Georgia Cancer Center; Leon Henri Charbonnier Endowed Chair of Pathology, Medical College of Georgia
    BIOGRAPHY
  • Complex Rearrangement Patterns in Undifferentiated Small Round Cell Sarcomas Associated with Poor Clinical Outcome
    JAN 12, 2022 10:00 AM PST

    Complex Rearrangement Patterns in Undifferentiated Small Round Cell Sarcomas Associated with Poor Clinical Outcome

    Juan Diaz-Martin, PhD
    Research Associate - IBiS-HUVR
    BIOGRAPHY
  • The Chromosomal Alteration Landscape of Mesothelioma
    JAN 12, 2022 9:40 AM PST

    The Chromosomal Alteration Landscape of Mesothelioma

    Matthew Couger, PhD
    Lead Investigator - Brigham and Women's Hospital
    BIOGRAPHY
  • Optical Genome Mapping Reveals Novel Structural Variants in Pediatric Brain Tumors
    JAN 12, 2022 9:10 AM PST

    Optical Genome Mapping Reveals Novel Structural Variants in Pediatric Brain Tumors

    Miriam Bornhorst, MD
    Clinical Director Gilbert Family Neurofibromatosis Institute, Medical Director Cancer Genetics Program - Children's National Hospital
    BIOGRAPHY
  • Vigor and Reproducibility in Research:  The Cell Line Saga:  Is OGM the Answer?
    JAN 12, 2022 8:55 AM PST

    Vigor and Reproducibility in Research: The Cell Line Saga: Is OGM the Answer?

    Gopalrao Velagaleti, PhD
    Professor and Director - Department of Pathology and Laboratory Medicine, UT Health - San Antonio
    BIOGRAPHY
  • Optical Genome Mapping in Unexplained High-Risk Breast Cancer Families
    JAN 12, 2022 8:35 AM PST

    Optical Genome Mapping in Unexplained High-Risk Breast Cancer Families

    Tuomo Mantere
    Cancer and Translational Medicine Research Unit and Biocenter Oulu, University of Oulu, Finland
    BIOGRAPHY
  • Optical Genome Mapping Application for Diagnosis of Non-Haematological Cancers
    JAN 12, 2022 8:20 AM PST

    Optical Genome Mapping Application for Diagnosis of Non-Haematological Cancers

    Elena García Sánchez, PhD
    Post-doctoral Researcher - FIB Hospital Infantil Universitario Niño Jesús
    BIOGRAPHY
  • A Year in Review:  Parallel Testing of Hematologic Malignancies using Optical Genome Mapping Compared to Conventional Cytogenetics.
    JAN 11, 2022 10:55 AM PST

    A Year in Review: Parallel Testing of Hematologic Malignancies using Optical Genome Mapping Compared to Conventional Cytogenetics.

    Adam Smith, MSc, PhD, FCCMG, FACMG, erCLG
    Director, Cancer Cytogenetics Laboratory - Laboratory Medicine Program University Health Network - Toronto
    BIOGRAPHY
  • Shining a New Light on Cancer Cytogenetics:  Leveraging Novel Technological Approaches for Improved Understanding in B-ALL
    JAN 11, 2022 10:35 AM PST

    Shining a New Light on Cancer Cytogenetics: Leveraging Novel Technological Approaches for Improved Understanding in B-ALL

    Adrian Dubuc, PhD, FACMG
    Associate Professor and Director (Microarray), Hematopathology and Molecular Diagnostics Laboratory
    BIOGRAPHY
  • Assessing Genomic Aberrations in AML using Optical Genome Mapping: Insights from a National Multi-Center Study
    JAN 11, 2022 10:05 AM PST

    Assessing Genomic Aberrations in AML using Optical Genome Mapping: Insights from a National Multi-Center Study

    Brynn Levy, M.Sc.(Med)., Ph.D., FACMG
    Professor of Pathology & Cell Biology at CUMC - Columbia University Medical Center
    BIOGRAPHY
  • Technical and Clinical Validation of Optical Genome Mapping
    JAN 11, 2022 9:35 AM PST

    Technical and Clinical Validation of Optical Genome Mapping

    Kornelia Neveling, PhD
    Scientific Researcher Translational Genomics, Radboud - University Medical Center, Nijmegen, The Netherlands
    BIOGRAPHY
  • Optical Genome Mapping for Diagnosis of Paediatric Leukaemia
    JAN 11, 2022 9:30 AM PST

    Optical Genome Mapping for Diagnosis of Paediatric Leukaemia

    Elena García Sánchez, PhD
    Post-doctoral Researcher - FIB Hospital Infantil Universitario Niño Jesús
    BIOGRAPHY
  • Opportunities of Optical Genome Mapping for Genetic Diagnosis in Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia
    JAN 11, 2022 9:20 AM PST

    Opportunities of Optical Genome Mapping for Genetic Diagnosis in Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia

    Ir. Barbara Dewaele, PhD
    Laboratory Geneticist - University Hospitals Leuven
    BIOGRAPHY
  • The Hidden Side of Genomic Complexity: Learning from OGM in Chronic Lymphocytic Leukemia
    JAN 11, 2022 9:00 AM PST

    The Hidden Side of Genomic Complexity: Learning from OGM in Chronic Lymphocytic Leukemia

    Anna Puiggros, PhD
    Assistant Biologist, Hospital del Mar - Barcelona
    BIOGRAPHY
  • The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia
    JAN 11, 2022 8:35 AM PST

    The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia

    Jonathan Lühmann, MSc
    PhD Student - Molecular Medicine at the Hannover Medical School, Germany
    BIOGRAPHY
  • Characterization of Plasma Cell Dyscrasias (PCD) by Optical Genome Mapping
    JAN 11, 2022 8:20 AM PST

    Characterization of Plasma Cell Dyscrasias (PCD) by Optical Genome Mapping

    Bence Dvoràk, MSc. Biomedical Sciences
    Oncology Lab - University Children's Hospital Zurich - Eleonore Foundation
    BIOGRAPHY
  • Enhanced Structural Variation Detection with Optical Genome Mapping in Constitutional Genetic Disorders
    JAN 10, 2022 10:15 AM PST

    Enhanced Structural Variation Detection with Optical Genome Mapping in Constitutional Genetic Disorders

    Nikhil Sahajpal, PhD.
    Post-doctoral Fellow, Augusta University
    BIOGRAPHY
  • Validation Study of Optical Genome Mapping for Postnatal and Prenatal Clinical Testing According to Established NYSDOH Guidelines
    JAN 10, 2022 10:00 AM PST

    Validation Study of Optical Genome Mapping for Postnatal and Prenatal Clinical Testing According to Established NYSDOH Guidelines

    M Anwar Iqbal, PhD, FFACMGG
    Professor and Director, DNA microarrayCGH Laboratory - University of Rochester Medical Center
    BIOGRAPHY
  • Optical Genome Mapping: Mapping Difficult Structural Variant Types - Repeat Expansions
    JAN 10, 2022 9:15 AM PST

    Optical Genome Mapping: Mapping Difficult Structural Variant Types - Repeat Expansions

    Alexander Hoischen, PhD
    Associate Professor Genomic Technologies & Immuno-Genomics - Radboud University Medical Center, Nijmegen, The Netherlands
    BIOGRAPHY
  • Clinical Utility of Optical Genome Mapping in a Constitutional Cytogenetics Laboratory
    JAN 10, 2022 8:50 AM PST

    Clinical Utility of Optical Genome Mapping in a Constitutional Cytogenetics Laboratory

    Shirley Heggarty, BSc., PhD, FRC Path Molecular Genetics
    Consultant Clinical Scientist - Belfast Health and Social Care Trust
    BIOGRAPHY
  • Balanced Translocations Associated with Male Infertility: How Optical Genome Mapping Could Lead to New Discoveries?
    JAN 10, 2022 8:35 AM PST

    Balanced Translocations Associated with Male Infertility: How Optical Genome Mapping Could Lead to New Discoveries?

    Laïla El Khattabi, PharmaD, PhD
    Associate Professor Genomic Technologies & Immuno-Genomics, APHP - Université de Paris
    BIOGRAPHY
  • Clinical Validation of Optical Genome Mapping for Preimplantation Genetic Diagnosis - Structural Rearrangement (PGD-SR) Applications
    JAN 10, 2022 8:20 AM PST

    Clinical Validation of Optical Genome Mapping for Preimplantation Genetic Diagnosis - Structural Rearrangement (PGD-SR) Applications

    Chaim Jalas
    Chief Operations Officer and Director of Technology Development, Foundation for Embryonic Competence
    BIOGRAPHY

Speakers


  • Chaim Jalas
    Chaim Jalas

    Chief Operations Officer and Director of Technology Development, Foundation for Embryonic Competence

    BIOGRAPHY
  • Laïla El Khattabi, PharmaD, PhD
    Laïla El Khattabi, PharmaD, PhD

    Associate Professor Genomic Technologies & Immuno-Genomics, APHP - Université de Paris

    BIOGRAPHY
  • Shirley Heggarty, BSc., PhD, FRC Path Molecular Genetics
    Shirley Heggarty, BSc., PhD, FRC Path Molecular Genetics

    Consultant Clinical Scientist - Belfast Health and Social Care Trust

    BIOGRAPHY
  • Alexander Hoischen, PhD
    Alexander Hoischen, PhD

    Associate Professor Genomic Technologies & Immuno-Genomics - Radboud University Medical Center, Nijmegen, The Netherlands

    BIOGRAPHY
  • M Anwar Iqbal, PhD, FFACMGG
    M Anwar Iqbal, PhD, FFACMGG

    Professor and Director, DNA microarrayCGH Laboratory - University of Rochester Medical Center

    BIOGRAPHY
  • Nikhil S. Sahajpal, PhD.
    Nikhil S. Sahajpal, PhD.

    Post-doctoral Fellow, Augusta University

    BIOGRAPHY
  • Bence Dvoràk, MSc. Biomedical Sciences
    Bence Dvoràk, MSc. Biomedical Sciences

    Oncology Lab - University Children's Hospital Zurich - Eleonore Foundation

    BIOGRAPHY
  • Jonathan L. Lühmann, MSc
    Jonathan L. Lühmann, MSc

    PhD Student - Molecular Medicine at the Hannover Medical School, Germany

    BIOGRAPHY
  • Anna Puiggros, PhD
    Anna Puiggros, PhD

    Assistant Biologist, Hospital del Mar - Barcelona

    BIOGRAPHY
  • Ir. Barbara Dewaele, PhD
    Ir. Barbara Dewaele, PhD

    Laboratory Geneticist - University Hospitals Leuven

    BIOGRAPHY
  • Elena García Sánchez, PhD
    Elena García Sánchez, PhD

    Post-doctoral Researcher - FIB Hospital Infantil Universitario Niño Jesús

    BIOGRAPHY
  • Kornelia Neveling, PhD
    Kornelia Neveling, PhD

    Scientific Researcher Translational Genomics, Radboud - University Medical Center, Nijmegen, The Netherlands

    BIOGRAPHY
  • Brynn Levy, M.Sc.(Med)., Ph.D., FACMG
    Brynn Levy, M.Sc.(Med)., Ph.D., FACMG

    Professor of Pathology & Cell Biology at CUMC - Columbia University Medical Center

    BIOGRAPHY
  • Adrian Dubuc, PhD, FACMG
    Adrian Dubuc, PhD, FACMG

    Associate Professor and Director (Microarray), Hematopathology and Molecular Diagnostics Laboratory

    BIOGRAPHY
  • Adam C. Smith, MSc, PhD, FCCMG, FACMG, erCLG
    Adam C. Smith, MSc, PhD, FCCMG, FACMG, erCLG

    Director, Cancer Cytogenetics Laboratory - Laboratory Medicine Program University Health Network - Toronto

    BIOGRAPHY
  • Saurabh Gupta, Ph.D., DABMGG
    Saurabh Gupta, Ph.D., DABMGG

    Chief Director, Quest Diagnostics

    BIOGRAPHY
  • Tuomo Mantere
    Tuomo Mantere

    Cancer and Translational Medicine Research Unit and Biocenter Oulu, University of Oulu, Finland

    BIOGRAPHY
  • Gopalrao Velagaleti, PhD
    Gopalrao Velagaleti, PhD

    Professor and Director - Department of Pathology and Laboratory Medicine, UT Health - San Antonio

    BIOGRAPHY
  • Miriam Bornhorst, MD
    Miriam Bornhorst, MD

    Clinical Director Gilbert Family Neurofibromatosis Institute, Medical Director Cancer Genetics Program - Children's National Hospital

    BIOGRAPHY
  • Matthew Brian Couger, PhD
    Matthew Brian Couger, PhD

    Lead Investigator - Brigham and Women's Hospital

    BIOGRAPHY
  • Juan Diaz-Martin, PhD
    Juan Diaz-Martin, PhD

    Research Associate - IBiS-HUVR

    BIOGRAPHY
  • Ravindra Kolhe, MD, PhD
    Ravindra Kolhe, MD, PhD

    Associate Dean for Translational Research; Associate Director for Genomics, Georgia Cancer Center; Leon Henri Charbonnier Endowed Chair of Pathology, Medical College of Georgia

    BIOGRAPHY
  • Mariangela Sabatella, PhD
    Mariangela Sabatella, PhD

    Postdoctoral Fellow

    BIOGRAPHY
  • Gordana Raca, MD
    Gordana Raca, MD

    Director of the Cytogenomics Laboratory in the Center for Personalized Medicine in the Department of Pathology and Laboratory Medicine at Children's Hospital Los Angeles

    BIOGRAPHY
  • Arran Constantine, BSc Biochemistry
    Arran Constantine, BSc Biochemistry

    Scientist - Bit.bio

    BIOGRAPHY
  • Saumyaa Saumyaa
    Saumyaa Saumyaa

    Senior Scientist - AstraZeneca

    BIOGRAPHY
  • Jens Luebeck, PhD
    Jens Luebeck, PhD

    Postdoctoral Researcher - University of California, San Diego

    BIOGRAPHY
  • Rashmi Kanagal-Shamanna, MD
    Rashmi Kanagal-Shamanna, MD

    Associate Professor and Director (Microarray), Hematopathology and Molecular Diagnostics Laboratory, MD Anderson Cancer Center

    BIOGRAPHY
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