MAR 14, 2018 9:00 AM PDT

3D Dilemma of This Century

Presented at: Neuroscience 2018
Speaker
  • Professor of Psychiatry and Behavioral Sciences, Obstetrics and Gynecology, Director, Center for Neuroscience in Women's Health, Stanford University School of Medicine
    BIOGRAPHY

Abstract

Most neuropsychiatric diseases involve multifactorial systems characterized by complex interactions among genetic predisposition/resiliency, environmental/social determinants, molecular sequelae and brain network organization. The allostatic load affects remodeling of brain architecture and physiological processes in response to stressors. The epigenetic allostasis emphasizes the influence of early-life experiences on the development of neuropsychiatric pathology in susceptible individuals. This presentation will cover the neurobiological frameworks underlying three main components of allostatic load – oxidative stress, inflammation and insulin resistance (IR) while accounting for genetic (familial) and epigenetic (early-life trauma) in human models. 


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MAR 14, 2018 9:00 AM PDT

3D Dilemma of This Century

Presented at: Neuroscience 2018


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