SEP 14, 2017 06:00 AM PDT

BENEFICIAL MICROBES: Sharing of the Microbial Informational Library

C.E. CREDITS: P.A.C.E. CE | Florida CE
  • Professor Emeritus, West Virginia University School of Medicine
      Professor Emeritus John G. Thomas, PhD, is recognized as an "International Educator and Global Microbiologist " ( having lectured in more than 43 countries while a clinical microbiologist in pathology (Professor), dentistry (Clinical Professor) and Graduate School Education (Adjunct Professor) for 54 years , his research emphasizing biofilms and medical devices. He has recently focused upon micro 3-D- bio Printing of contour fitting gauzes using bio-plastics and unique Prebiotics with Therapeutic Bacteria (Beneficial Bacteria) for chronic wound intervention (SMarT Gauze); this integrates a common pathway, visualized through his 'Microbial Clock' and recently created Center of Hologenomic Clinical Studies ( Center) which underscores a "Dual Citizenship" and co evolution of symbiotic microbes and human ecosystems. "Microbes Matter". His Probiotic Solutions integrates Computer Decision Support for Probiotic (Beneficial Bacteria) Guidelines combining AI, Artificial Intelligence and Precision Medicine, expanded recently to emphasize Chronic Wound Care and Aging, hypothesized now as a disease.
      He has over 50 publications, multiple book chapters and significant grant support. His military obligation (1969-71)(wounds) and his sabbatical at Cardiff University, Wales, UK (2007)(oral health, biofilms) have remained a driving catalyst. He has been a member of the American Dental Association Scientific Advisory Committee for the last 8 years and American Society of Microbiology for 54 years.
      As Faculty at 3 national (Northeastern Ohio Universities College of Medicine, Rutgers University and West Virginia University) and 2 international Universities ( National University of Singapore and Cardiff University) during his career , he has received multiple Alumni and University awards for research and Student Mentoring ; retiring from West Virginia University in 2013 after 23 years as Professor Emeritus , he presently is expanding his research/teaching utilizing the advanced resources of the Allegheny Health Network (Center of Excellence in Biofilm Research) and Carnegie -Mellon University, Pittsburg, PA, and Mass. Gen. Hospital (Dept. of Anesthesia and Critical Care) with Harvard University, Boston, MA, all under the umbrella of his Global Microbiology Consulting. (GMC) (


    INTRODUCTION:  The recent coincidental emergence of the human microbiota and the Hologneomic Theory of Co-evolution unmasked the “Dual Citizenship” of symbiotic microbes and human ecosystems, sharing of 2 global “Passports” and our themes that “Microbes Matter“ and “Don’t Trash your Microbiota/Mycobiota.”  It also unmasked the concept of Beneficial Microbes (both bacteria and fungi), where given the overwhelming genetic strength of our microbial microbiota and the interface in disease and health, created a new concept of “self”. SCIENCE:  Here, we highlight Beneficial Microbes (BM) in 5 parts.  Part 2, addresses the “What”, including definitions, while unmasking the variety of BMs (Search, Homing, Destroy), emphasizing the unique role of biofilms as a key ingredient and the genetic strength within.  Part 3 addresses “How” BMs work, focusing on 4 neuro-pharmacologic pathways and 3 established axial pathways:  GUT, skin and vagina. Parts 4 and 5 bring clinical application and our unique amalgamation of our research to patient care. Part 4 utilizes our “Microbial Clock”, visualizing 10 metabolic endogenous diseases linked by a common pathway, including Aging, a recent NIH postulation, and Chronic Wounds, an exogenous disease where missing microbiota and mycobiota could be a central theme.  Part 5 focuses on intervention in both, recognizing “restorative microbiology” and the use of probiotics as BMs in “organ transplants” using our Computer Assisted Decision Support via  Bac-2-Health and Partners-4-Life data bases, organized for the public and health care professionals education. It is the beginning of “Precision Medicine”, the linking of Artificial Intelligence (AI) with disease management algorithms, integrating BMs. CONCLUSION: “We live in a Microbial World” with apologies to Madonna, which has been victimized by Louis Pastuer/Robert Koch themes as mostly pathogenic. One Health should be the new theme, maximized by utilization of the genetic strength of microbes as a benefit, recognizing caution and the down-stream impact on industry, clinical laboratories and our “psyche”.      

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