Several clinical and preclinical studies implicate abnormal endocannabinoid functioning and neuroinflammation as possible mechanisms in the pathophysiology of autism. Correcting these abnormalities may result in reducing or alleviating symptoms such as anxiety, aggression, insomnia, and self-injurious behaviors. We will also discuss the possible benefits and adverse effects that may be attributed to the use of cannabis in this population.
1. To understand how and why cannabis therapy broadly impacts maladaptive behaviors commonly seen in autistic patients.
2. To be able to weigh the possible benefits and risks of cannabis therapy in this population.