Characterization of N-linked glycans with the Released Glycans Workflow of MassHunter Bioconfirm Software

Monoclonal antibodies are heterogeneous molecules that include glycosylation variants, carboxyl truncation, and deamidation that require extensive analytical characterization. These molecules are one of the fastest growing classes in the biopharmaceutical industry. This presentation will discuss a complete workflow for intact monoclonal antibody analysis with the use of the 6545XT AdvanceBio LC/Q-TOF platform and automatic data processing with MassHunter BioConfirm software.