Postdoctoral Fellow Department of Physiology, Louisiana State University Health Sciences Center
BIOGRAPHY
JUL 31, 2019 9:00 AM PDT
Share
Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
Speaker
Abstract
DATE: July 31, 2019
TIME: 9:00am PT, 12:00pm ET
The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricles, produces cerebrospinal fluid, and protects the brain via a physical barrier. Perivascular macrophages line the stromal capillaries through it, and tight junctions between the apical sides of the epithelial cells regulate the microenvironment. The choroid plexus is also believed to be an immune interface between peripheral and CNS immune systems and plays a major role in the resolution of neuroinflammation by recruiting monocytes and leukocytes into the CNS. It has also been proposed to be a target of viral infection, such as a human immunodeficiency virus (HIV) reservoir, and a site of damage in cerebral hemorrhage, stroke, and hypoxia. Since the choroid plexus can allow transmigration of leukocytes, recruit myeloid cells, control diffusion of small molecules and water, and control drug permeability into the CSF, it is important to have an ex-vivo culture model.
We designed a rhesus macaque 2D choroid plexus epithelial cell culture, as well as a modified 3D cell culture model, in order to study activation, diffusion, and migration through the choroid plexus. Our hope was to be able to understand the response of the blood-CSF barrier to peripheral HIV infection, as the rhesus macaque is an ideal animal model of infection. This model can also be used to study pro- and anti-inflammatory challenges, as well as barrier properties.
Learning Objectives:
- To understand history, development, & function of the Blood-CSF Barrier
- Understanding the pathology & therapeutic potential of the Choroid Plexus
- Designing a 2D and modified 3D Choroid Plexus epithelial cell model system
Webinars will be available for unlimited on-demand viewing after live event.
LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.
You May Also Like
MAY 11, 2021
10:00 AM PDT
C.E. CREDITS
MAY 11, 2021
10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
SEP 14, 2021
7:00 AM PDT
C.E. CREDITS
SEP 14, 2021
7:00 AM PDT
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
JUN 09, 2021
7:00 AM PDT
C.E. CREDITS
JUN 09, 2021
7:00 AM PDT
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
JUL 15, 2021
9:00 AM PDT
JUL 15, 2021
9:00 AM PDT
Date: July 15, 2021 Time: 9:00am (PDT), 12:00pm (EDT) The Pisces workflow robust, easy-to-use, end-to-end multi-omics solution for highly multiplexed targeted Spatial RNA analysis. VeranomeB...
JUL 15, 2021
8:00 AM PDT
C.E. CREDITS
JUL 15, 2021
8:00 AM PDT
Date: July 15, 2021 Time: 8:00am (PDT), 11:00am (EDT) High dimensional full spectrum flow cytometry grants unprecedented access to previously unattainable parameters in cellular biology. Flu...
Date: November 17, 2021 Time: 8:00am (PDT), 11:00am (EDT) From waste disposal to promising biomarkers and therapeutic agents, exosomes and other extracellular vesicles are valuable in resear...
JUL 31, 2019 9:00 AM PDT
Share
Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
Specialty
Molecular Biology
Cell Biology
Cell Culture
Cancer Research
Immunology
Biotechnology
Biomarkers
Molecular Diagnostics
Biochemistry
Clinical Research
Genetics
Microbiology
Cancer Diagnostics
Biology
Dna
Geography
North America58%
Europe18%
Asia14%
South America4%
Africa4%
Oceania1%
Registration Source
Website Visitors45%
Email Promotions32%
WAVE Newsletter Promotion8%
Trending Newsletter Promotion2%
Social Media Promotions1%
Client/Sponsor Promotions1%
Other12%
Job Title
Research Scientist18%
Student17%
Scientist9%
Medical Laboratory Technician9%
Educator/Faculty9%
Executive7%
Clinical Laboratory Scientist7%
Medical Doctor/Specialist7%
Lab Management5%
Post Doc5%
Facility/Department Manager4%
Biologist2%
Consultant1%
Organization
Academic Institution31%
Hospital15%
Research Institute7%
Clinical Laboratory6%
Medical School5%
Biotech Company5%
Medical Center4%
Government4%
Non-Profit Organization3%
Life Science Company3%
Pharmaceutical Company2%
Contract Research Organization (Cro)1%
Consultant1%
Ambulatory Care1%
Other5%
Loading Comments...
Finish Registering
-
NOV 03, 2021Opioid Crisis 2021 -
NOV 09, 2021IonWorld 2021
-
NOV 10, 2021Clinical Diagnostics & Research 2021
-
FEB 23, 2022Drug Discovery & Development 2022
-
MAR 10, 2022Neuroscience 2022
- See More
-
OCT 20, 2021
-
OCT 20, 2021
- See More
![Is It the Junk [DNA] That Makes Our Brains Human?](https://d3bkbkx82g74b8.cloudfront.net/eyJidWNrZXQiOiJsYWJyb290cy1pbWFnZXMiLCJrZXkiOiJjb250ZW50X2FydGljbGVfcHJvZmlsZV9pbWFnZV80ZWFhZTU0ZGNmZmYzMjQ3NjRhOWQzN2RkYmI4MzQ1OGJkYWNhZjI3Xzg5NjkucG5nIiwiZWRpdHMiOnsidG9Gb3JtYXQiOiJqcGciLCJyZXNpemUiOnsid2lkdGgiOjMwMCwiaGVpZ2h0IjoxNTAsImZpdCI6ImNvdmVyIiwiYmFja2dyb3VuZCI6IiNmZmYifSwiZmxhdHRlbiI6eyJiYWNrZ3JvdW5kIjoiI2ZmZiJ9fX0=)
