MAR 28, 2018 9:00 AM PDT

Controlling Terpenes and Cannabinoids in Flower and Extract

Speaker
  • Founder & CEO, Complex Biotech Discovery Ventures
    Biography
      Dr. Roggen's latest project, Complex Biotech Discovery Ventures, a fundamental research laboratory and CRO of the cannabis industry. His research interests lie in the metabolite composition and behavior throughout the production cycle, SFE process optimization, and development of innovative therapeutic formulations. Dr. Roggen received his master in science degree from Imperial College, London, UK in 2008. He then pursued his graduate degree is organic chemistry at the Federal Institute of Technology in Zürich (ETHZ), where he received his PhD in 2012. He then was awarded an DAAD postdoctoral fellowship to pursue further training in physical organic chemistry at The Scripps Research Institute in La Jolla from 2013-2014. He then entered the cannabis industry, at first as laboratory director for Davinci Laboratories of California, an analytical laboratory from 2014 to 2016. In 2016 he moved into an executive position overseeing production, R&D and process optimization for OutCo, a cannabis manufacturer. Dr. Markus Roggen is also a trusted advisor and mentor for multiple startups, startup accelerators and organizations. Positions include advisory positions at Bloom Automation, a cannabis robotics company, Redfield Proctor, a waste management company, and former co-chair of the NCIA Scientific Advisory Committee.

    Abstract

    Cannabis and its products are referred to in the USA as Medical Marijuana. The traditional approach to medical research of a single compound for a single target does not work for cannabis, as its medical benefits lie in the “entourage effect”.1 Likely more than just THC and CBD are participating in any medical effects, be it any of the other >100 known cannabinoids, >200 terpenes and terpenoids or flavonoids.2 Therefore, the cannabis field had adopted a strain/cultivar approach to judge effects for the patient. Although, we can agree that not the plant morphology but the chemical makeup3,4 of the cannabis product will be the underlying cause of any physiological effect. Furthermore, such chemical makeups are not only dictated by the strain/cultivar, but also influenced grow methods, drying and curing, and also the extraction method.

    In this talk, I present our research at OutCo of how to effect and control the chemical makeup of flower and extracts. We have devised protocols to monitor the dry and cure of cannabis flowers in a way that we are able to modulate the terpene and cannabinoid profiles in our strain offering. Additionally, extensive research has been put into controlling, modulating and customizing the chemical makeup of cannabis extracts. We can show that not every extract is the same, but all offer different benefits on a molecular level. The talk will present our latest findings in this exciting field of cannabis research.

    Learning Objectives:

    • In this presentation you will learn about a cannabis extract on a molecular level
    • In this presentation you will learn how a cannabis extract can be customized

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