Thomas Doktor is a molecular biologist turned bioinformatician. He has been working on understanding human diseases caused by splicing mutations, in particular neuromuscular disorders and metabolic syndromes. His research interests are mainly focused around developing analysis tools and pipelines to investigate mRNA splicing, with a focus on deciphering the splicing code and identifying regulatory elements that can be used to control splicing, e.g. by blocking regulatory elements using nanotechnology such as antisense oligonucleotides. This enables both the study of the splicing process in detail and the design of drugs to correct defective splicing in patients. In recent years, the availability of next generation sequencing (NGS) has made it possible to investigate normal and aberrant mRNA splicing on a global scale, and exhaustive analysis of this type of data is at the core of his research interests.