FEB 24, 2016 6:00 AM PST

Emerging role of liquid biopsies and NGS for biomarker discovery

Speaker
  • Senior Global Product Manager, QIAGEN
    Biography
      Raed Samara, PhD is a Global Product Manager for NGS technologies at QIAGEN, with a focus on pre-analytics and targeted enrichment. Prior to joining QIAGEN, he was a postdoctoral fellow at the National Cancer Institute conducting research in the field of cancer immunology with emphasis on identifying strategies to boost the efficacy of cancer vaccines. He received his Ph.D. degree from Georgetown University in tumor biology.

    Abstract

    Precision medicine promises a more effective approach to disease treatment and management. It is based on analyzing mutations of disease samples to unlock mechanisms of disease development and progression, and resistance to effective therapies. Recent advances in NGS have made it the ideal approach for the comprehensive analysis of the mutational landscape of samples. Specifically, the ability to enrich certain genomic targets known, or suspected, to harbor driver mutations prior to NGS is allowing researchers to achieve very deep levels of sequencing coverage, levels that cannot be achieved by either WGA or WES, thereby increasing the sensitivity of NGS assays. The ability to enrich genomic targets has also facilitated the use of liquid biopsies for the discovery of mutations that contribute to drug resistance. Several challenges remain though, mainly the specificity and uniformity of target enrichment approaches, the amount of required DNA, and the turnaround time needed to go from sample to insight. Attend this seminar to learn what solutions QIAGEN scientists have developed to overcome these challenges and how these solutions can be used to analyze mutations in a wide range of samples such as FFPE, cfDNA, and CTCs, thereby enabling researchers to use solid and liquid biopsies for disease management and, ultimately, precision medicine.


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    FEB 24, 2016 6:00 AM PST

    Emerging role of liquid biopsies and NGS for biomarker discovery


    Specialty

    Research And Development

    Gene Expression

    Dna

    Big Data

    Cancer Research

    Tumor

    Biomarkers

    Cancer

    Earth Science

    Oncology

    University

    Gene Sequencing

    Drug Discovery

    Mass Cytometry

    Cell Culture

    Geography

    Asia50%

    Europe50%

    Registration Source

    Website Visitors100%

    Job Title

    Student50%

    Medical Laboratory Technician50%

    Organization

    Manufacturer - Other50%

    Academic Institution50%


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