SEP 28, 2017 10:30 AM PDT

Engineering stem cell biology for disease modelling and therapeutics

Presented At Cell Biology 2017
C.E. CREDITS: P.A.C.E. CE | Florida CE
Speakers
  • Postdoctoral Associate, University of Wisconsin-Madison
    Biography
      Amr Abdeen received his Bachelors of Science from the German University in Cairo at 2010 in materials science and engineering. He pursued his PhD in materials science under the supervision of prof. Kristopher Kilian at the University of Illinois at Urbana-Champaign, where he studied biomaterials for the control of adult stem cells. His thesis focused on controlling mesenchymal stem cell angiogenic potential via biomaterials methods. He joined the Wisconsin Institute for Discovery in 2016, where his current work focuses on CRISPR based gene editing in multiple cell types, including pluripotent stem cells.

    Abstract:

    Stem cells can self-renew and differentiate into multiple different cell types. Engineering of stem cells has enabled new methods to study development and organogenesis in humans as well as develop new disease models and therapies. Stem cells can be obtained from multiple sources in vivo or generated in the lab. Engineering of pluripotent stem cells, for example, can potentially generate any tissue in the body and can be used for tissue repair or organoid formation. Furthermore, advances in gene editing technologies have enabled precise editing of stem cell genomes, creating possibilities for establishment of models for diseases and personalized therapies. In this lecture I will discuss the sources and properties of various stem cells as well as their utilization in modelling, therapy and tissue engineering. 


    Show Resources
    You May Also Like
    APR 27, 2018 10:00 AM PDT
    C.E. CREDITS
    APR 27, 2018 10:00 AM PDT
    DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
    MAY 03, 2018 11:00 AM PDT
    MAY 03, 2018 11:00 AM PDT
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    MAY 24, 2018 09:30 AM PDT
    C.E. CREDITS
    MAY 24, 2018 09:30 AM PDT
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    MAY 22, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 22, 2018 08:00 AM PDT
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    AUG 15, 2018 08:00 AM PDT
    C.E. CREDITS
    AUG 15, 2018 08:00 AM PDT
    DATE: August 15, 2018TIME: 08:00AM PDT, 11:00AM EDTThe failure of current chemotherapeutic strategies in the fight against cancer can be largely attributed to the occurrence of drug res...
    JUN 29, 2018 09:00 AM PDT
    C.E. CREDITS
    JUN 29, 2018 09:00 AM PDT
    DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
    Loading Comments...
    Show Resources