As VP of Nonclinical Sciences, Joseph Senn oversees all nonclinical development, Toxicology, pathology, DMPK, Clinical pharmacology and in vivo pharmacology, across Moderna and its ventures. Prior to joining Moderna, Dr. Senn was director and site head for Drug Safety Evaluation and therapeutic area lead for immunology at Takeda Pharmaceuticals. . Dr. Senn is a board certified toxicologist who received his PhD in Pharmacology and Physiology from the University of Rochester School of Medicine and Dentistry. He has held joint faculty positions at the Medical University of South Carolina as assistant professor of pediatrics and pharmacology prior to entering industry. In industry, his focus has been on immunotoxicology, investigative, discovery and development toxicology. Over his time in industry he has supported the development of programs in a wide range of therapeutic areas including immune modulators, oncology, neurology, inflammatory and infectious diseases. He has led multiple regulatory filings for modalities ranging from small molecules, biologics and antibody drug conjugates and most recently modified messenger RNA.