SEP 02, 2015 9:00 AM PDT

Keynote: Immunology and the Microbiome

Presented at: Microbiology
Speaker
  • Environmental Microbiologist, Department of Biosciences, Argonne National Laboratory - Associate Professor, University of Chicago Departments of Ecology&Evolution and Surgery - Senior Scient
    Biography
      Dr. Jack A Gilbert earned his Ph.D. from Nottingham University, UK in 2002, and received his postdoctoral training in Canada at Queens University. He subsequently returned to the UK in 2005 and worked for Plymouth Marine Laboratory as a senior scientist until his move to Argonne National Laboratory and the University of Chicago in 2010. Dr. Gilbert is currently applying next-generation sequencing technologies to microbial metagenomics and metatranscriptomics to test fundamental hypotheses in microbial ecology. He has authored more than peer reviewed 120 publications and book chapters on metagenomics and approaches to ecosystem ecology (www.gilbertlab.com). He has focused on analyzing microbial function and diversity, community assembly processes, and dynamic interactions between taxa, with an aim of predicting the metabolic output from a community. He is currently working on generating observational and mechanistic models of microbial communities in natural, urban, built and human ecosystems. He is on the board of the Genomic Standards Consortium (www.gensc.org), is an section editor for PLoS ONE and senior editor for the ISME Journal and Environmental Microbiology, and is PI for the Earth Microbiome Project (www.earthmicrobiome.org), Home Microbiome Project (www.homemicrobiome.com), Gulf Microbial Modeling Project (www.microbial-models.com), Hospital Microbiome Project (www.hospitalmicrobiome.com), and the Chicago River Microbiome Project.

    Abstract

    The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with these invaders. The immune system was refined over millions of years to control our interaction with the microbial world, and even to use it as a mechanism of defense, food processing, and vitamin production. The immune system and the microbiome have shaped each other in extraordinarily elaborate and intricate ways. Here we will discuss some of the recent evidence highlighting these mechanisms of interaction. We will also discuss how the last 150 years, have started to disturb the delicate balance of the immune-microbe equilibrium. As our natural ecosystem has been restricted to the built environment, especially in the developed world, where an average of 90% of our lives take place indoors, our exposure to the microbial world has been corrupted. Modern buildings are equipped with surfaces and environmental systems designed to reduce the potential for microbial life to flourish. This fundamental shift in our lifestyle is likely impacting the development and function of our immune systems in ways that we are only beginning to understand.


    Show Resources
    You May Also Like
    APR 07, 2020 8:00 AM PDT
    C.E. CREDITS
    APR 07, 2020 8:00 AM PDT
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    MAY 08, 2020 10:00 AM PDT
    C.E. CREDITS
    MAY 08, 2020 10:00 AM PDT
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    JUN 17, 2020 1:30 PM PDT
    C.E. CREDITS
    JUN 17, 2020 1:30 PM PDT
    Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
    FEB 19, 2020 11:00 AM PST
    C.E. CREDITS
    FEB 19, 2020 11:00 AM PST
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    AUG 27, 2020 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    AUG 27, 2020 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: August 27, 2020 TIME: 7:00am PT Novel anti-viral medications, including biologics and small molecule inhibitors, as well as serologic diagnostic tool sets are in urgent demand to fight...
    FEB 26, 2020 9:00 AM PST
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    Loading Comments...
    Show Resources
    Attendees
    • See more