DEC 05, 2019 9:00 AM PST

Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments

Speakers
  • Senior Product Application Scientist, NanoString
    Biography
      Dr. Mathias Holpert is working as a Sr. Product Application Scientist (EMEA) at NanoString. In this role, he is responsible for training users on the GeoMx Digital Spatial Profiler platform and for consultation and support of customer projects. He received a Diploma in Biology from the university of Würzburg, Germany and a Doctors degree (Dr. rer. nat.) from the university of Göttingen, Germany.
    • Director, Advanced Staining Innovation, Leica Biosystems
      Biography
        Traci DeGeer is the Director, Advanced Staining Innovation, Leica Biosystems. In this capacity she helps access new technologies for the Life Science research business, manages relationships with partners, works with legal partners to put agreements in place and liaises with Business Units to meet partner/customer needs as technologies are being developed. Traci holds a Bachelor of Science, in Biology, an HT, HTL, and QIHC for the anatomic pathology lab and recently graduated the HBx core program. Traci also holds a patent in small molecule detection for PDL-1 and has spoken at over one hundred state, regional and global symposia on various topics. Traci also sits on the ASCP Board of Certification (HT, HTL and QIHC Exam) and is the current Education Chair for the National Society of Histotechnology.

      Abstract
      DATE:  December 5, 2019
      TIME:   9:00am PST, 12:00pm EST
       
      Characterization of the spatial distribution and abundance of proteins and mRNAs with morphological context within tissues enables a better understanding of biological systems in many research areas, including immunology, oncology and neuropathology. Analysis of samples across multiple tumor types and diseases has revealed novel spatially distinct protein and mRNA candidate biomarkers. However, it has proven difficult to perform such studies in a highly multiplexed manner at a throughput scale that is required for translational research programs. To address this unmet need, we have developed a novel platform that can perform high-plex analysis of proteins or mRNAs on a single FFPE section from distinct tissue spatial regions (GeoMxTM Digital Spatial Profiler, DSP). Integrating the GeoMx DSP with either the NanoString nCounter or high-throughput sequencing, hundreds or thousands of spatially resolved analytes can be measured. To enhance both throughput and reproducibility, we have developed automated sample processing workflows for both protein and RNA on Leica Biosystem's BOND RX system. In this webinar, we will show you how the integrated workflows of the Leica BOND RX and the GeoMx DSP can advance your translational research.
       
      Learning Objectives
      • Demonstrate how the spatial profiling workflow can be used to gather multiplexing information. 
      • Describe how the spatial profiling workflow is similar and where it diverges from more traditional multiplexing methodologies.
       
       
      For research use only. Not for use in diagnostic procedures.
       
       
      Webinars will be available for unlimited on-demand viewing after live event.
       
      LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

      Show Resources
      You May Also Like
      DEC 02, 2020 8:00 AM PST
      Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
      C.E. CREDITS
      DEC 02, 2020 8:00 AM PST
      Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
      DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
      SEP 10, 2020 9:00 AM PDT
      C.E. CREDITS
      SEP 10, 2020 9:00 AM PDT
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      OCT 08, 2020 7:00 AM PDT
      C.E. CREDITS
      OCT 08, 2020 7:00 AM PDT
      DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
      NOV 16, 2020 8:00 AM PST
      C.E. CREDITS
      NOV 16, 2020 8:00 AM PST
      Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
      NOV 18, 2020 8:00 AM PST
      C.E. CREDITS
      NOV 18, 2020 8:00 AM PST
      DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
      OCT 29, 2020 6:00 AM PDT
      C.E. CREDITS
      OCT 29, 2020 6:00 AM PDT
      Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
      Loading Comments...
      Show Resources
      Attendees
      • See more