OCT 26, 2017 12:00 PM PDT

WEBINAR: Overcoming Challenges in the Cellular Therapy Laboratory

Sponsored by: TERUMO BCT
Speaker
  • Director, GMP for Immunotherapy Assistant Professor at Children's National and GWU
    Biography
      Dr. Hanley is the director of the class 10,000 GMP facility at Children's National Health System, which is charged with manufacturing novel cellular therapies in the Program for Cell Enhancement and Technology for Immunotherapy (CETI) under IND applications, as well as processing standard-of-care stem cell transplant products. He is also responsible for follow-up and immune reconstitution testing performed on patients treated on CETI's protocols. For the past 10 years, he has investigated and helped to translate the following into more than 15 clinical trials:
      • Virus-specific T-cells for the prophylaxis and treatment of viral infections after transplant
      • Tumor-specific T-cells using endogenous receptors and chimeric antigen receptors
      • A GMP-compliant method of manufacturing MSCs using the Quantum® Cell Expansion System for patients after stroke, graft-versus-host disease and inflammatory bowel disease
      Dr. Hanley has been recognized as a developing expert in the field of cellular therapy and cellular therapy product manufacturing, and he has been granted the Excellence in Research award by the American Society of Gene and Cell Therapy in 2012 and the Young Investigator award by the Intl. Society for Cell Therapy (ISCT) in 2013 and 2016. In 2017, he was awarded the Be The Match/American Society of Blood and Marrow Transplantation (ASBMT) Amy Strelzer Manasevit award. He previously served on the trainee council of the American Society of Hematology, and he was selected for the prestigious American Society of Hematology/European Hematology Association Translational Research training program in 2013. In addition to translating cellular therapies from bench to clinic, Dr. Hanley is passionate about developing dedicated training programs for budding cellular therapists, particularly programs dedicated to training scientists in positions within the cellular therapy laboratory, such as laboratory facility management, quality assurance, manufacturing and quality control.

    Abstract

    DATE: October 26, 2017
    TIME: 12:00 PM PDT

    This presentation will focus on recent advances in cellular therapy—from mesenchymal stromal cells (MSCs) to tumor-specific T-cells. More specifically, we will discuss how these cells are made in our academic good manufacturing practice (GMP) facility, how we try to meet the demands of our investigators and what challenges we must overcome to expand these therapies.

    Who may this interest:

    • Clinicians, researchers, laboratory technologists
    • Cell therapy manufacturing professionals 
    • Gene and immunotherapy manufacturing professionals

    Learning Objective:
    Identify challenges associated with early-stage cell therapy manufacturing and potential solutions

     

     


    Show Resources
    You May Also Like
    DEC 02, 2020 8:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    DEC 02, 2020 8:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    OCT 08, 2020 7:00 AM PDT
    C.E. CREDITS
    OCT 08, 2020 7:00 AM PDT
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    SEP 10, 2020 9:00 AM PDT
    C.E. CREDITS
    SEP 10, 2020 9:00 AM PDT
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    AUG 25, 2020 8:00 AM PDT
    C.E. CREDITS
    AUG 25, 2020 8:00 AM PDT
    DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
    JUN 23, 2020 10:00 AM PDT
    C.E. CREDITS
    JUN 23, 2020 10:00 AM PDT
    DATE: June 23, 2020 TIME: 10:00am PT Human mesenchymal stromal or stem cells (MSCs)-based immunomodulation treatment has been proposed as a suitable therapeutic approach for many diseases, s...
    OCT 29, 2020 6:00 AM PDT
    C.E. CREDITS
    OCT 29, 2020 6:00 AM PDT
    Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
    Loading Comments...
    Show Resources
    Attendees
    • See more