Associate Professor of Pediatrics, University of Toronto, Hemostasis and Thrombosis Service, The Hospital for Sick Children
Dr. Leonardo Brandao is a native Brazilian who obtained his medical degree at University of Sao Paulo (USP). After doing post-graduate training at the same institution, he pursued training in North America in Pediatrics (Emory University, Atlanta, Georgia), Pediatric Hematology/Oncology (St. Jude Children's Research Hospital, Memphis, Tennessee) and Pediatric Coagulation (Weill Cornell University, New York, New York). In brief, his North American training initially included a fellowship at St. Jude's Children's Research Hospital, where he was actively involved in studying clinical coagulation laboratory tools in children with acute lymphoid leukemia, as well as working in a gene therapy laboratory to study the expression of antithrombin by different cell lines. This was followed by training in pediatrics/coagulation (Emory University), where he developed and coordinated research projects on bleeding (pediatric bleeding score, platelet function defects). During his second fellowship training at Weill Cornell University, his research was solely focused on pediatric coagulation, in the management of both bleeding (new laboratory tools for phenotype definition in hemophilia) and thrombosis (the role of inherited thrombophilia in venous thrombosis) in children. He is currently a staff member with the Hemostasis and Thrombosis Service. This is Canada's largest referral based-tertiary hospital. Because of its' privileged position in the field of pediatric thrombosis, Sickkids® continues to be instrumental in the development of the field of pediatric thrombosis, by participating in several dose finding studies for several of the new anticoagulants in children, as well as other prospective clinical research studies (i.e. perfusion medicine, cardiology, pediatric thrombosis). Dr. Brandao is also actively involved in the field of coagulation in children with congenital heart defects, in the area of long-term thrombosis outcome (i.e. post-thrombotic syndrome), and in the subject of coagulation derangements in children with vascular anomalies.