AUG 22, 2017 5:00 PM JST

ケーススタディ: 治療用細胞製造のスケールアップ

Sponsored by: TERUMO BCT
Speakers
  • Sr. Manager, Global Strategic Medical Affairs, Cell Therapy Technologies - Terumo BCT
    Biography
      Jim recently transitioned to the Global Strategic Medical Affairs team to better leverage both his technical background and the commercial exposure he has gained during his more than seven years at Terumo BCT. Prior to joining the cell processing team at Terumo BCT, Dr. Beltzer was the lead scientist for the research and development of Synthemax™, a synthetic growth surface for the culture of human embryonic stem cells, at Corning Life Sciences. He was a co-founder of RETT Corporation and was a key player in the industrialization of several technology platforms, including phage display and yeast two-hybrid. He has more than 25 years of industrial research and development experience in a broad range of disciplines.

    Abstract:

    DATE: August 23, 2017
    TIME: 9:00AM JST

    OR

    DATE: August 22, 2017
    TIME: 5:00PM PDT, 6:00PM MDT

     

    機能的閉鎖式の自動細胞培養プロセスを使用した T 細胞増殖、ウイルスベクター製造、および間葉系幹細胞(MSC)のスケールアップ製造について、詳しくご説明します。

    Beltzer 博士(Terumo BCT、米国コロラド州)が、医療業界と医学界の両方において達成されたプロセス開発および経済面の目標に関する、多数のケーススタディをご紹介します。例えば、T 細胞を 12 日間で最大 500 倍に増殖した事例、同種治療用細胞の商品原価(COG)を 40 パーセント削減した事例、フラスコベースのプロセスと同等の力価を実現した自動ウイルスベクター製造の事例などがあります。特に、こうした目標を達成するために必要になることが多いプロセス変更に注目します。


    対象
    • 臨床医、研究者、検査技師、細胞治療業界の担当者
    • 治療用細胞製造の担当者
    • 遺伝子免疫療法製造の担当者

     

    Learning Objectives:

    • 中空糸バイオリアクターシステムを使用した、T 細胞増殖の新たな事例
    • 間葉系幹細胞(MSC)の製造をスケールアップするためのテクニック
    • ウイルスベクター製造への新たなアプローチ
    • コストおよび労力削減を実現したケーススタディ

    Show Resources
    You May Also Like
    JAN 23, 2020 9:00 AM PST
    C.E. CREDITS
    JAN 23, 2020 9:00 AM PST
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    NOV 18, 2019 7:00 AM PST
    C.E. CREDITS
    NOV 18, 2019 7:00 AM PST
    DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
    AUG 27, 2019 9:00 AM PDT
    C.E. CREDITS
    AUG 27, 2019 9:00 AM PDT
    DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
    SEP 05, 2019 4:00 PM CEST
    C.E. CREDITS
    SEP 05, 2019 4:00 PM CEST
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    FEB 25, 2020 9:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    FEB 25, 2020 9:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
    MAR 03, 2020 9:00 AM JST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    MAR 03, 2020 9:00 AM JST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: March 3, 2020 TIME: 9:00am JST A major limitation in the ex vivo expansion of harvested human hematopoietic stem-progenitor cells (HSPCs) is the rapid differentiation of HSPCs at the e...
    Loading Comments...
    Show Resources