FEB 03, 2016 3:00 PM PST

The Future of Preclinical Animal Models in Pharmaceutical Discovery and Development: How the Scientific 3Rs of Relevance, Robustness and Reproducibility are Critical

Speaker
  • Director of Comparative Biology and Medicine, GlaxoSmithKline, Adjunct Professor of Pathology, Duke University School of Medicine
    BIOGRAPHY

Abstract

Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the pharmaceutical discovery and development process on the use of animal models has come under increasing scrutiny for ethical and scientific reasons. There have been several prominent papers that have reported limited concordance of animal experiments with subsequent human clinical trials. Recent assessments of the quality of animal studies have suggested that this translational failure may be due in part to shortcomings in the planning, conduct and reporting of in vivo studies. This talk will emphasize methods to assure best practice rigor in animal study methods and reporting. It will introduce the so-called “scientific 3Rs” of Relevance, Robustness, and Reproducibility to the In vivo study approach, and will review important new trends in the pharmaceutical discovery and development communities.


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FEB 03, 2016 3:00 PM PST

The Future of Preclinical Animal Models in Pharmaceutical Discovery and Development: How the Scientific 3Rs of Relevance, Robustness and Reproducibility are Critical


Specialty

Animal Research

Animal Models

Immunology

Biotechnology

Bioinformatics

Drug Discovery

Inflammation

Animal Behavior

Cancer Research

Biomarkers

Research And Development

Lab Animals

Animals

T-Cells

Cancer

Geography

Europe70%

North America20%

South America10%

Registration Source

Website Visitors100%

Job Title

Scientist30%

Medical Laboratory Technician20%

Research Scientist20%

Student10%

Medical Doctor/Specialist10%

Animal Care Lab Technician10%

Organization

Pharmaceutical Company40%

Academic Institution30%

Research Institute30%


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