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We are leading the way in developing integrated online sampling and Process Analytical Technology (PAT) workflows for quick monitoring of critical quality attributes (CQA) to produce advance...
Endonuclease Cas12a, as one key part of the CRISPR/Cas biotechnology, possessed a unique dual enzymatic function which has been widely used for various applications1. However, the limits tra...
Advanced therapy medicinal products (ATMPs) are ‘living drugs’ that have proven highly effective at treating diseases, such as cancer, that were once thought untreatable. As &lsq...
How can labs increase their sample throughput and pipetting accuracy and reproducibility without investing in an expensive automated liquid handler? Electronic pipettes are a cost-effective...
In this talk, I will introduce two new tools that we developed based on CRISPR-enabled gene regulation in bacteria, and one method based on P1 phagemid-enabled delivery of Cas9 nuclease. Fir...
Brain cancer research stands to benefit from the perspectives, tools, and methodologies of non-traditional fields, such as mechanical engineering. Here, I will discuss our engineering-based...
Over the past 25 years, Luminex’s xMAP® Technology has emerged as the worldwide leader in bead-based multiplexing. The new xMAP® INTELLIFLEX platform combines the proven perfor...
Neural networks are a powerful tool for modeling neural activity in the brain. In this talk, I will discuss how these models have helped in my own research and highlight recent work building...
Almost unidimensional in their primordial existence as single cells, multicellular organisms quickly develop into complex 3D architectures and machineries composed of multiple cells and tiss...
Most hospital systems have implemented opioid-related stewardship programs. That is an important first step. This talk will take that work to the next level, describing four advanced concept...
Gene regulatory networks are representations of the relationship between transcription factors and their target genes. By modeling gene regulatory networks, it is possible to identify change...
The arenaviruses are an important group of pathogens that includes several agents of severe human disease, with symptoms that include hemorrhagic fever and neurological complications; howeve...
Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...
This talk will provide an overview of our work in the design of self-assembled, functionalised peptide and protein nanoparticles, hydrogels and bio-interfaces for applications in healthcare....
Actin cytoskeleton is essential for eukaryotic cells. To exert its countless cellular functions, actin undergoes dynamic remodeling orchestrated by the large number of actin-interacting fact...
Today, the majority of cell biology operations are carried out manually, even though the core steps are highly reproducible. Staff are expected to conduct repetitive tasks for hours each day...
Immunotherapy has changed the landscape of oncology, improving survival rates for many patients across a variety of malignancies. Two antibody-based immunotherapies, immune checkpoint inhibi...
In recent years substance-related overdoses, many of which involve opioids, have contributed to more deaths than car accidents. Opioid Use Disorder (OUD) is a medical condition that continue...
Common buckwheat (Fagopyrum esculentum Moench; 2n = 2x =16) is an outcrossing pseudocereal widely cultivated in the temperate zone. Buckwheat is fast-growing and is tolerant of cool climates...
Black Americans have an increased risk for age-related cognitive decline and Alzheimer's disease (AD) compared to other ethnic and racialized groups. However, risk factors for age-relate...
There are known outcome disparities between Black and White patients with pancreatic neuroendocrine tumors (pNETs). Multiple retrospective series have found that Black patients have more adv...
Background and aim: G protein-coupled receptors (GPCRs) are vital membrane proteins involved in cellular and physiological processes, including sensory perception, signaling, neurotransmissi...
Cytokine storm is suspected of producing the overzealous immune response driving the severe cardiopulmonary complications that fuel high morbidity and mortality rates in certain COVID-19 inf...