Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
Borrelia burgdorferi, the causative agent of Lyme disease, cycles between an Ixodes spp. vector and a vertebrate reservoir host, typically small rodents. Humans become infected when they int...
During my research career I have worked to further understanding of how intracellular organisation changes in response to the needs and environment of the living cell, focusing on the regula...
Infectious disease monitoring on Oxford Nanopore Technologies (ONT) platforms offers rapid turnaround times and low cost. Tracking low frequency intra-host variants provides important insigh...
Rapid, accurate, and wide-spread COVID-19 testing is essential for contact tracing, timely triaging of patients, and viral monitoring. The current gold standard for COVID-19 testing is RT-PC...
Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
The field of gene therapy has enabled the treatment and potential cures for serious, monogenetic diseases. This form of advanced therapy relies on the delivery of the “correct” c...
Cells in their natural environment are surrounded by a complex extracellular matrix that provides structure and functional cues to the surrounding cells. Hydrogels can be used to approximate...
Learning Objectives: 1. Understand the Analytical Quality by Design Principles 2. Learn about the benefits of using specialized software for rapid and robust method development....
Artificial neural networks can be useful for studying brain functions. In cognitive neuroscience, recurrent neural networks are often used to model cognitive functions. I will first offer my...
Radiation therapy is an important cornerstone of oncologic therapy but is feared to the point of intimidation by too many patients. Yet by the end of treatment, most patients find the experi...
Rapid, accurate and frequent detection of the RNA of SARS-CoV-2 and of serological host antibodies to the virus would facilitate the determination of the immune status of individuals who hav...
Immune checkpoint blockade has revolutionized the treatment for patients with cancer. Great efforts remain to better understand resistant mechanisms to treatment as well as means to improve...
Background: Healthcare access (HCA) encompasses five important dimensions: Affordability, Availability, Accessibility, Accommodation and Acceptability. Published studies of cancer typically...
Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis...
Experience the Revolution of DNA Polymerase Technology: Choosing the Best DNA Polymerase for Efficient PCR Workflows. PCR has revolutionized modern molecular biology, but its success would n...
We will show how to combine large scale neural recordings and mechanistic neural network models to advance our conceptual understanding of how neural circuits mediate cognitive functions lik...
Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
Immunotherapy such as immune checkpoint inhibitor antibodies have revolutionized the treatments for hard-to-treat cancers, with durable responses observed in clinics. However, the overall re...
Highly efficacious vaccines against COVD-19 have been generated in a record time, and allowed a great impact in preventing severe disease due to SARS-CoV-2 infection in vaccinated individual...
Human induced pluripotent stem cells (iPSCs) are immortal cell lines that can be derived from skin or blood of any individual. Their unique property of pluripotency means they can be differe...
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is a novel virus that causes COVID-19 and has considerable variability in clinical outcomes among infected patients. The GENCOV stu...
Primary resistance to CD19-directed chimeric antigen receptor T-cell therapy (CART19) occurs in 10% to 20% of patients with acute lymphoblastic leukemia (ALL); however, the mechanisms of thi...
Accurate characterization of monoclonal antibodies is essential to development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess...
Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
With recent emergences in new infectious diseases and their variants, there is a need to develop faster and more specific analytical tools to detect different respiratory infectious diseases...
Alzheimer’s and Parkinson’s diseases (AD, PD) are the two most common neurodegenerative disorders. Both diseases are characterized by abnormal aggregates in the brain, which incl...
My laboratory uses tools from pharmacology, genomics, and cell signaling to study two key aspects of cancer biology. First, we seek to understand how oncogenic signals, altered metabolic sta...
Borrelia burgdorferi, the causative agent of Lyme disease, cycles between an Ixodes spp. vector and a vertebrate reservoir host, typically small rodents. Humans become infected when they int...
