This compilation of webinars touch on the various human diseases are most commonly attributed to the subject matter of microbiology, as well as the many microbes that are also responsible for numerous beneficial processes.
Microbes are recently recognized as driving the energy and nutrient transformations that fuel Earth’s ecosystems in soils, oceans and humans. Where studied, viruses appear to modulate...
Innate and adaptive immunity mechanisms provide antiviral protection in mammals. In this talk, I shall present recent findings from my lab and collaborators revealing a distinct form of mamm...
Influenza infections are initiated by just a handful of virions infecting a handful of cells, so it is important to understand what happens in single infected cells. I will describe work tha...
The detection and analysis of traces for the purpose of providing clues in criminal investigations has a rich history that dates back to the mid-18th Century. Traces are remnants of past eve...
The immune system evolved to protect us against pathogen invasion and to maintain tissue homeostasis. Fundamental for these functions are the interferons (IFNs), a group of cytokines that be...
Short tandem repeats (STRs) are gold-standard genetic loci used for source attribution of evidentiary material in legal matters. Their power lies in their high heterozygosity and large allel...
Infection with human immunodeficiency virus (HIV)-1 compromises the immune system and causes in about half of the affected individuals neurological and neurocognitive complication categorize...
Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing an...
The selective pressure placed on the resident microbiota by local changes in the host environment – DNA damage, chronic inflammation, metabolic shifts, barrier damage, reduced immunosu...
Asthma is an increasing health concern affecting more than 25 million individuals in the United States and more than 300 million individuals worldwide. In some cases, sensitization or exposu...
Human skin is characterized by a limited number of phyla including, Actinomycetota, Bacillota and Pseudomonadota. In particular, Staphylococcus (Bacillota) and Corynebacterium (Actinomycetot...
The encapsulated fungus Cryptococcus neoformans is the most common cause of fungal meningitis, with the highest rate of cryptococcosis found in AIDS patients. Despite antifungal treatment, c...
While viral fusion proteins are highly desirable for subunit vaccine generation, their inherent metastable nature complicates implementation and development. We have harnessed the structural...
Influenza viruses represent a significant burden to human health. In order to limit respiratory viral disease, new approaches that can prevent viral infection and spread are needed. We have...
Flow cytometry is a powerful technology for investigating questions related to the immune response and its sustenance, as well as detailed mechanisms of COVID-19. Simplified cell-based and b...
A significant increase in agricultural production is needed to meet the demand for food to feed the expected ~10 billion people by 2050. This increased agricultural output will also require...
Traditionally, virology has been focused in studying the pathogenic effect of viruses. In the recent years, however, this perception is changing and viruses are being studied as mutualistic...
Ribonucleic acid (RNA) has a breathtaking variety of biological functions, which far exceeds its classical role as a carrier of genetic information. The repertoire of this versatile molecule...
Epidemics are occurring at an increasing pace and scale. Our laboratory group has developed platform technologies for discovery of broad and potent neutralizing antibodies for many emerging...
The COVID-19 pandemic is a dramatic reminder of the problems that viral zoonoses can cause worldwide. The rapid development of vaccines and antivirals......
Lessons around leveraging high-complexity next-generation sequencing tests for precision infectious disease discovery to guide patient treatment and improve health outcomes. Learning Objecti...
In Pacific Northwest watersheds several species of Pacific salmonid fishes are hosts for the rhabdovirus infectious hematopoietic necrosis virus (IHNV). In this multi-host ecosystem speciali...
Saliva serves as a reservoir for the upper aerodigestive tract (UADT). Saliva collection is non-invasive, convenient, and amenable to self-collection. Thus, saliva is an ideal resource for l...
Plant-infecting viruses cause significant losses to agriculture, including to staple crops such as wheat, maize, and rice. Preventing and managing endemic and emerging plant diseases is an o...
Adjuvant discovery is largely devoted toward the development of vaccines meant to elicit prophylactic humoral immunity. While useful against infectious diseases, this mode of adaptive immuni...
Infectious diseases have been a major threat to human health throughout history, causing significant economic damage worldwide. In modern medicine, quickly and accurately identifying the ger...
Over the past decade, the availability and feasibility for clinical laboratories of all sizes to implement molecular platforms has grown exponentially. No longer does a laboratory need to be...
Microbes are recently recognized as driving the energy and nutrient transformations that fuel Earth’s ecosystems in soils, oceans and humans. Where studied, viruses appear to modulate...
