Research models are used in medical research to mimic aspects of a disease or illness that occurs in humans. Research models can include animals (in vivo models), cell lines (in vitro models), or computer-driven demonstrations (in silico models). Research models allow doctors and scientists to uncover important information that can be applied to clinical practice.
Date: March 23, 2021 Time: 9:00am (PST), 12:00pm (EST) The chromatin regulators CBP and p300 maintain gene expression programs through lysine acetylation of chromatin and transcriptional reg...
Date: March 11, 2021 Time: 8:00am (PST), 11:00am (EST) g the toxicity profile of a compound is a necessity across industries and the various stages of drug development. Early stage mechanism...
Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
The concept of the 3Rs remains more prevalent than ever in global discussions related to humane animal use in aspects of research, teaching and testing. The 3Rs serve as a touchstone, in ter...
Primates have been essential in unlocking novel immune mechanisms that have driven development of groundbreaking new drugs in infectious disease and transplantation, amongst others related t...
Traditional drug discovery often begins with simple biochemical and transformed cellular models, advances to more complex animal models in late discovery phases, and often does not ‘se...
The International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) Microphysiological Systems (MPS) Affiliate is a group of pharmaceutical industry scientists who see...
Remarkable progress in life science and technology in the past century has advanced our fundamental understanding of the human body beyond our imagination. The ever-increasing knowledge of h...
Since the first introduction of the 3R concept in 1959 by Russell and Burch, there has been an increasing interest in finding alternatives to animal testing for ethical and economic reasons....
Learning Objectives: 1. Define an effective in vitro tissue model 2. Identify the features of a microvasculature 3. Explain the approaches for building in vitro tissue models...
Many of the most debilitating and life-threatening diseases are associated with the central nervous system. Some, such as neurodegenerative diseases, predominately afflict our aging populati...
There is growing concern about the reliability of biomedical research results. Poor experimental design, inappropriate analysis methods and incomplete reporting have all contributed to incon...
Learning Objectives: 1. Methods on how to aseptically use foil (Reynolds Wrap) in rodent surgery 2. Methods on how aseptically use cling film (Press N' Seal) in rodent surgery 3. Long-te...
Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
Date: February 4, 2021 Time: 8:00am (PST), 11:00am (EST) Over the last several years, there has been increased interest around the use of patient derived organoids for personalized medicine...
In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
Date: February 3, 2021 Time: 8:00am (PST), 11:00am (EST) This introduction webinar will provide you with an overview of the general immuno-oncology (IO) research field...
Date: December 04, 2020 Time: 5:00am PDT, 2:00pm CET Diabetes Mellitus has become a worldwide epidemic, affecting approximately 425 million people. Unfortunately, one in two patients remain...
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
SARS-CoV-2 had spread with speed unknown in recent history across the globe, sickening >50M people and killing over 1M. By far the most of the severe cases and deaths were registered amon...
Antibody tests are important tools to assess the efficacy of vaccine candidates and to derive suitable vaccination modalities. High specificity and sensitivity are of great importance for th...
DATE: December 2, 2020 TIME: 9:00am PDT Pluripotent stem cell (PSC) research is a continuously evolving field that beholds great promises for the future. The great application potential of P...
Date: March 23, 2021 Time: 9:00am (PST), 12:00pm (EST) The chromatin regulators CBP and p300 maintain gene expression programs through lysine acetylation of chromatin and transcriptional reg...
Date: March 11, 2021 Time: 8:00am (PST), 11:00am (EST) g the toxicity profile of a compound is a necessity across industries and the various stages of drug development. Early stage mechanism...
Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
The concept of the 3Rs remains more prevalent than ever in global discussions related to humane animal use in aspects of research, teaching and testing. The 3Rs serve as a touchstone, in ter...
Primates have been essential in unlocking novel immune mechanisms that have driven development of groundbreaking new drugs in infectious disease and transplantation, amongst others related t...
Traditional drug discovery often begins with simple biochemical and transformed cellular models, advances to more complex animal models in late discovery phases, and often does not ‘se...
The International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) Microphysiological Systems (MPS) Affiliate is a group of pharmaceutical industry scientists who see...
Remarkable progress in life science and technology in the past century has advanced our fundamental understanding of the human body beyond our imagination. The ever-increasing knowledge of h...
Since the first introduction of the 3R concept in 1959 by Russell and Burch, there has been an increasing interest in finding alternatives to animal testing for ethical and economic reasons....
Learning Objectives: 1. Define an effective in vitro tissue model 2. Identify the features of a microvasculature 3. Explain the approaches for building in vitro tissue models...
Many of the most debilitating and life-threatening diseases are associated with the central nervous system. Some, such as neurodegenerative diseases, predominately afflict our aging populati...
There is growing concern about the reliability of biomedical research results. Poor experimental design, inappropriate analysis methods and incomplete reporting have all contributed to incon...
Learning Objectives: 1. Methods on how to aseptically use foil (Reynolds Wrap) in rodent surgery 2. Methods on how aseptically use cling film (Press N' Seal) in rodent surgery 3. Long-te...
Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
Date: February 4, 2021 Time: 8:00am (PST), 11:00am (EST) Over the last several years, there has been increased interest around the use of patient derived organoids for personalized medicine...
In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
Date: February 3, 2021 Time: 8:00am (PST), 11:00am (EST) This introduction webinar will provide you with an overview of the general immuno-oncology (IO) research field...
Date: December 04, 2020 Time: 5:00am PDT, 2:00pm CET Diabetes Mellitus has become a worldwide epidemic, affecting approximately 425 million people. Unfortunately, one in two patients remain...
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
SARS-CoV-2 had spread with speed unknown in recent history across the globe, sickening >50M people and killing over 1M. By far the most of the severe cases and deaths were registered amon...
Antibody tests are important tools to assess the efficacy of vaccine candidates and to derive suitable vaccination modalities. High specificity and sensitivity are of great importance for th...
DATE: December 2, 2020 TIME: 9:00am PDT Pluripotent stem cell (PSC) research is a continuously evolving field that beholds great promises for the future. The great application potential of P...
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