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    Research model

    Research models are used in medical research to mimic aspects of a disease or illness that occurs in humans. Research models can include animals (in vivo models), cell lines (in vitro models), or computer-driven demonstrations (in silico models). Research models allow doctors and scientists to uncover important information that can be applied to clinical practice.

    Webinars

    • AUG 21, 2014 | 6:45 AM
      Development and Applications of CRISPR-Cas9 for Genome Editing
      Development and Applications of CRISPR-Cas9 for Genome Editing
      The Cas9 endonuclease from the microbial adaptive immune system CRISPR can be easily programmed to bind or cleave specific DNA sequence using a short RNA guide. Cas9 is enabling the generatio...
      Speaker: Feng Zhang, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      79
      AUG 20, 2014 | 12:30 PM
      Integrative Systems Approaches to Network Modeling of Biological Processes
      Integrative Systems Approaches to Network Modeling of Biological...
      ...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      44
      AUG 20, 2014 | 8:00 AM
      Exploring Complex Structural Genomic Variation using Next-Gen Sequencing
      Exploring Complex Structural Genomic Variation using Next-Gen...
      Structural variants (SVs), defined as the deletion, duplication, insertion, inversion or translocation of genomic regions, are both a major source of genetic diversity in human populations an...
      Speaker: Ryan E. Mills, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      AUG 20, 2014 | 8:00 AM
      High-resolution genomic analysis reveals genetic impacts of human papillomavirus in human cancers
      High-resolution genomic analysis reveals genetic impacts of human...
      One of the hallmarks of human cancers is genetic instability. My colleagues and I recently identified a remarkable association between human papillomavirus (HPV) and genomic structural variat...
      Speaker: David E Symer, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      4
      AUG 20, 2014 | 7:15 AM
      Establishing cell-free biology for the production of therapeutics, materials, and chemicals
      Establishing cell-free biology for the production of therapeutics,...
      Imagine a world in which we could adapt biology to manufacture any therapeutic, material, or chemical from renewable resources, both quickly and on demand. Industrial biotechnology is one of...
      Speaker: Michael C Jewett, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      11
      AUG 20, 2014 | 7:00 AM
      Human Genome Analysis
      Human Genome Analysis
      The ENCODE and modENCODE consortia have generated a resource containing large amounts of transcriptomic data, extensive mapping of chromatin states, as well as the binding locations of >30...
      Speaker: Mark B Gerstein, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      MAY 29, 2014 | 10:30 AM
      Why are we unable to lose weight and keep it off? All about the connection between the gut and the brain
      Why are we unable to lose weight and keep it off? All about the...
      Obesity is a disease. It was once not considered to be a disease and to be a matter of will power and gluttony. It was also the case that we once thought that fat tissue had no metabolic func...
      Speaker: Caroline M Apovian, MD, FACP, FACN
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      53
      MAY 29, 2014 | 10:30 AM
      Adding Value in Healthcare Delivery: Uses for Clinical Laboratory Informatics in Decision Support
      Adding Value in Healthcare Delivery: Uses for Clinical Laboratory...
      Clinical laboratory information provides decision support for most healthcare providers and impacts care processes and patient outcomes throughout the entire health services delivery system....
      Speaker: Elizabeth Kenimer Leibach, EdD, MS, MLS(ASCP), SBB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      70
      MAY 29, 2014 | 9:00 AM
      Keynote Panel Discussion: Companion Diagnostics: Changing the Face of Healthcare, Doctors Hawkins, Joseph, and Frank
      Keynote Panel Discussion: Companion Diagnostics: Changing the...
      What is the future of personalized medicine? Featuring Dr. Trevor Hawkins (An Introduction to Companion Diagnostics), Dr. Patrick Joseph (Making It Personal for Patients), and Dr. Richard Fra...
      Speaker: Patrick Joseph, MD and Richard Frank, MD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      82
      MAR 20, 2014 | 2:00 PM
      Disinhibition Drives Rapid Movement and Associative Motor Memory Formation in the Cerebellum
      Disinhibition Drives Rapid Movement and Associative Motor Memory...
      Motor coordination relies on accurate predictions that specify how the body should move in particular sensorimotor contexts. Although such predictions are thought to be stored as associative...
      Speaker: Paul Mathews, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 20, 2014 | 2:00 PM
      Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
      Cross-talk & Developmental Programs A Key to Translational...
      The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
      Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
      Presented at: Neuroscience Virtual Event Series 2014
      94
      MAR 20, 2014 | 1:00 PM
      The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
      The role of high throughput sequencing in the research and diagnosis...
      Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
      Speaker: Peter L Nagy, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 20, 2014 | 1:00 PM
      Neurogenesis, cognitive dysfunction and Alzheimer's disease
      Neurogenesis, cognitive dysfunction and Alzheimer's disease
      Neural stem cells exist in the adult mammalian brain throughout life. They reside in the subgranular layer of the dentate gyrus and in the subventricular zone. Neural stem cells have the capa...
      Speaker: Orly Lazarov, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      124
      MAR 20, 2014 | 11:00 AM
      Using brain imaging and biomarkers for diagnosis and investigation of Alzheimer's disease "The Alzheimer's Disease Neuroimaging Initiat
      Using brain imaging and biomarkers for diagnosis and investigation...
      Alzheimers disease (AD) is a neurodegenerative disorder producing cognitive impairment and dementia in millions of elders. Currently no treatment is effective to slow the progression of AD. M...
      Speaker: Michael Weiner, MD
      Presented at: Neuroscience Virtual Event Series 2014
      62
      MAR 20, 2014 | 10:00 AM
      Impairments of brain network connectivity in autism
      Impairments of brain network connectivity in autism
      With a rising prevalence recently exceeding 1%, autism spectrum disorder (ASD) has become a pressing public health issue. Crucial hurdles on the way to targeted treatments are (i) the relianc...
      Speaker: Ralph-Axel Mueller, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      94
      MAR 20, 2014 | 8:00 AM
      Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
      Cross-talk & Developmental Programs A Key to Translational Stem...
      The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
      Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      1
      MAR 20, 2014 | 7:00 AM
      Huntingtons Disease: Twenty years and counting
      Huntingtons Disease: Twenty years and counting
      Huntington's disease (HD) is a progressive, inherited, degenerative brain disorder that produces physical, mental and emotional changes. Named for George Huntington, the physician who fi...
      Speaker: Margaret Sutherland, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      106
      MAR 20, 2014 | 6:00 AM
      Connectomics - Defining Neural Circuits to Understand Brain Function
      Connectomics - Defining Neural Circuits to Understand Brain Function
      Connectomics is a new field of research that aims to map the synapses of the nervous system in order to construct a wiring diagram of all the neural circuits. It is necessary to use the elect...
      Speaker: Scott W. Emmons, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      54
      MAR 19, 2014 | 1:00 PM
      ABCA1 and APOE: Intertwined roles in Alzheimers disease
      ABCA1 and APOE: Intertwined roles in Alzheimers disease
      ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
      Speaker: Radosveta Koldamova, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      56
      MAR 19, 2014 | 12:00 PM
      Abeta oligomer receptor antagonists as disease-modifying Alzheimers therapeutics
      Abeta oligomer receptor antagonists as disease-modifying Alzheimers...
      Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic Amyloid beta (Abeta)1-42 oligomers is proposed to underlie cognitive decline in Alzheimers disease (AD). Syn...
      Speaker: Susan Catalano, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      46
      MAR 19, 2014 | 12:00 PM
      Src Regulation of Lamellipodia, Filopodia, and Substrate-Cytoskeletal Coupling in Neuronal Growth Cones
      Src Regulation of Lamellipodia, Filopodia, and Substrate-Cytoskeletal...
      Axonal growth and pathfinding is fundamental to the development and regeneration of the nervous system. Src tyrosine kinase has been implicated in this process; however, the detailed molecula...
      Speaker: Daniel Suter, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 19, 2014 | 9:00 AM
      Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic Plasticity
      Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic...
      Dendritic spine shape enables sequestering of subcellular components needed for synaptic plasticity, including polyribosomes for local protein synthesis, smooth endoplasmic reticulum (SER) to...
      Speaker: Kristen Harris, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      24
      MAR 19, 2014 | 8:00 AM
      BRAIN Initiative Panel Discussion - science overview
      BRAIN Initiative Panel Discussion - science overview
      The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By...
      Speaker: Emery N. Brown, MD, PhD, William Newsome, PhD, Justin Sanchez, PhD, Terrence J Sejnowski, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      59
      MAR 19, 2014 | 7:00 AM
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
      Speaker: Ahmad Salehi, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      15
    AUG 21, 2014 | 6:45 AM
    Development and Applications of CRISPR-Cas9 for Genome Editing
    Development and Applications of CRISPR-Cas9 for Genome Editing
    The Cas9 endonuclease from the microbial adaptive immune system CRISPR can be easily programmed to bind or cleave specific DNA sequence using a short RNA guide. Cas9 is enabling the generatio...
    Speaker: Feng Zhang, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    79
    AUG 20, 2014 | 12:30 PM
    Integrative Systems Approaches to Network Modeling of Biological Processes
    Integrative Systems Approaches to Network Modeling of Biological...
    ...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    44
    AUG 20, 2014 | 8:00 AM
    Exploring Complex Structural Genomic Variation using Next-Gen Sequencing
    Exploring Complex Structural Genomic Variation using Next-Gen...
    Structural variants (SVs), defined as the deletion, duplication, insertion, inversion or translocation of genomic regions, are both a major source of genetic diversity in human populations an...
    Speaker: Ryan E. Mills, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    AUG 20, 2014 | 8:00 AM
    High-resolution genomic analysis reveals genetic impacts of human papillomavirus in human cancers
    High-resolution genomic analysis reveals genetic impacts of human...
    One of the hallmarks of human cancers is genetic instability. My colleagues and I recently identified a remarkable association between human papillomavirus (HPV) and genomic structural variat...
    Speaker: David E Symer, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    4
    AUG 20, 2014 | 7:15 AM
    Establishing cell-free biology for the production of therapeutics, materials, and chemicals
    Establishing cell-free biology for the production of therapeutics,...
    Imagine a world in which we could adapt biology to manufacture any therapeutic, material, or chemical from renewable resources, both quickly and on demand. Industrial biotechnology is one of...
    Speaker: Michael C Jewett, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    11
     
     
  • AUG 20, 2014 | 7:00 AM
    Human Genome Analysis
    Human Genome Analysis
    The ENCODE and modENCODE consortia have generated a resource containing large amounts of transcriptomic data, extensive mapping of chromatin states, as well as the binding locations of >30...
    Speaker: Mark B Gerstein, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    MAY 29, 2014 | 10:30 AM
    Why are we unable to lose weight and keep it off? All about the connection between the gut and the brain
    Why are we unable to lose weight and keep it off? All about the...
    Obesity is a disease. It was once not considered to be a disease and to be a matter of will power and gluttony. It was also the case that we once thought that fat tissue had no metabolic func...
    Speaker: Caroline M Apovian, MD, FACP, FACN
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    53
    MAY 29, 2014 | 10:30 AM
    Adding Value in Healthcare Delivery: Uses for Clinical Laboratory Informatics in Decision Support
    Adding Value in Healthcare Delivery: Uses for Clinical Laboratory...
    Clinical laboratory information provides decision support for most healthcare providers and impacts care processes and patient outcomes throughout the entire health services delivery system....
    Speaker: Elizabeth Kenimer Leibach, EdD, MS, MLS(ASCP), SBB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    70
    MAY 29, 2014 | 9:00 AM
    Keynote Panel Discussion: Companion Diagnostics: Changing the Face of Healthcare, Doctors Hawkins, Joseph, and Frank
    Keynote Panel Discussion: Companion Diagnostics: Changing the...
    What is the future of personalized medicine? Featuring Dr. Trevor Hawkins (An Introduction to Companion Diagnostics), Dr. Patrick Joseph (Making It Personal for Patients), and Dr. Richard Fra...
    Speaker: Patrick Joseph, MD and Richard Frank, MD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    82
    MAR 20, 2014 | 2:00 PM
    Disinhibition Drives Rapid Movement and Associative Motor Memory Formation in the Cerebellum
    Disinhibition Drives Rapid Movement and Associative Motor Memory...
    Motor coordination relies on accurate predictions that specify how the body should move in particular sensorimotor contexts. Although such predictions are thought to be stored as associative...
    Speaker: Paul Mathews, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
     
     
  • MAR 20, 2014 | 2:00 PM
    Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
    Cross-talk & Developmental Programs A Key to Translational...
    The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
    Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
    Presented at: Neuroscience Virtual Event Series 2014
    94
    MAR 20, 2014 | 1:00 PM
    The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
    The role of high throughput sequencing in the research and diagnosis...
    Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
    Speaker: Peter L Nagy, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
    MAR 20, 2014 | 1:00 PM
    Neurogenesis, cognitive dysfunction and Alzheimer's disease
    Neurogenesis, cognitive dysfunction and Alzheimer's disease
    Neural stem cells exist in the adult mammalian brain throughout life. They reside in the subgranular layer of the dentate gyrus and in the subventricular zone. Neural stem cells have the capa...
    Speaker: Orly Lazarov, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    124
    MAR 20, 2014 | 11:00 AM
    Using brain imaging and biomarkers for diagnosis and investigation of Alzheimer's disease "The Alzheimer's Disease Neuroimaging Initiat
    Using brain imaging and biomarkers for diagnosis and investigation...
    Alzheimers disease (AD) is a neurodegenerative disorder producing cognitive impairment and dementia in millions of elders. Currently no treatment is effective to slow the progression of AD. M...
    Speaker: Michael Weiner, MD
    Presented at: Neuroscience Virtual Event Series 2014
    62
    MAR 20, 2014 | 10:00 AM
    Impairments of brain network connectivity in autism
    Impairments of brain network connectivity in autism
    With a rising prevalence recently exceeding 1%, autism spectrum disorder (ASD) has become a pressing public health issue. Crucial hurdles on the way to targeted treatments are (i) the relianc...
    Speaker: Ralph-Axel Mueller, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    94
     
     
  • MAR 20, 2014 | 8:00 AM
    Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
    Cross-talk & Developmental Programs A Key to Translational Stem...
    The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
    Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    1
    MAR 20, 2014 | 7:00 AM
    Huntingtons Disease: Twenty years and counting
    Huntingtons Disease: Twenty years and counting
    Huntington's disease (HD) is a progressive, inherited, degenerative brain disorder that produces physical, mental and emotional changes. Named for George Huntington, the physician who fi...
    Speaker: Margaret Sutherland, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    106
    MAR 20, 2014 | 6:00 AM
    Connectomics - Defining Neural Circuits to Understand Brain Function
    Connectomics - Defining Neural Circuits to Understand Brain Function
    Connectomics is a new field of research that aims to map the synapses of the nervous system in order to construct a wiring diagram of all the neural circuits. It is necessary to use the elect...
    Speaker: Scott W. Emmons, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    54
    MAR 19, 2014 | 1:00 PM
    ABCA1 and APOE: Intertwined roles in Alzheimers disease
    ABCA1 and APOE: Intertwined roles in Alzheimers disease
    ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
    Speaker: Radosveta Koldamova, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    56
    MAR 19, 2014 | 12:00 PM
    Abeta oligomer receptor antagonists as disease-modifying Alzheimers therapeutics
    Abeta oligomer receptor antagonists as disease-modifying Alzheimers...
    Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic Amyloid beta (Abeta)1-42 oligomers is proposed to underlie cognitive decline in Alzheimers disease (AD). Syn...
    Speaker: Susan Catalano, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    46
     
     
  • MAR 19, 2014 | 12:00 PM
    Src Regulation of Lamellipodia, Filopodia, and Substrate-Cytoskeletal Coupling in Neuronal Growth Cones
    Src Regulation of Lamellipodia, Filopodia, and Substrate-Cytoskeletal...
    Axonal growth and pathfinding is fundamental to the development and regeneration of the nervous system. Src tyrosine kinase has been implicated in this process; however, the detailed molecula...
    Speaker: Daniel Suter, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
    MAR 19, 2014 | 9:00 AM
    Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic Plasticity
    Age-Dependent Responses of Dendrite Structure to Hippocampal Synaptic...
    Dendritic spine shape enables sequestering of subcellular components needed for synaptic plasticity, including polyribosomes for local protein synthesis, smooth endoplasmic reticulum (SER) to...
    Speaker: Kristen Harris, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    24
    MAR 19, 2014 | 8:00 AM
    BRAIN Initiative Panel Discussion - science overview
    BRAIN Initiative Panel Discussion - science overview
    The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By...
    Speaker: Emery N. Brown, MD, PhD, William Newsome, PhD, Justin Sanchez, PhD, Terrence J Sejnowski, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    59
    MAR 19, 2014 | 7:00 AM
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
    Speaker: Ahmad Salehi, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    15
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