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    Antigen-specific T cells

    T cells, a type of CD8 T cells (also called cytotoxic T lymphocyte) that are activated against a specific antigen. CD8 T cells identify and eliminate foreign cells, such as cancer cells or virus-infected cells. Antigen specific T cells are capable of identifying a specific antigen that is specific to the invading cells.

    Webinars

    • JUN 02, 2021 | 12:00 AM
      Engineering universal chimeric antigen receptors (CARs) for cancer therapy
      Engineering universal chimeric antigen receptors (CARs) for cancer...
      Learning Objectives: 1. Define “universal CARs” and describe their mechanism of action. 2. Explain current challenges in CAR T cell therapy. 3. Describe potential benefits and ch...
      Speaker: Jason Lohmueller, Ph.D.
      Presented at: Immuno-Oncology Virtual Event Series 2021
      2
      JUN 02, 2021 | 12:00 AM
      EZH2 as an Actionable Therapeutic Target to Enhance Anti-Tumor Immune Response In Prostate Cancer
      EZH2 as an Actionable Therapeutic Target to Enhance Anti-Tumor...
      Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
      Speaker: Leigh Ellis, Ph.D.
      Presented at: Immuno-Oncology Virtual Event Series 2021
      1
      JUN 02, 2021 | 12:00 AM
      Development of FGFR4 targeted Chimeric Antigen Receptors (CARs) for treatment of Rhabdomyosarcoma
      Development of FGFR4 targeted Chimeric Antigen Receptors (CARs)...
      Rhabdomyosarcoma (RMS) is a soft tissue cancer commonly arising in muscle and is the most common soft tissue cancer in children. Patients with metastatic RMS have a poor prognosis that has n...
      Speaker: Peter Sullivan, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2021
      1
      JUN 02, 2021 | 12:00 AM
      Using genetically engineered preclinical models to study T cell therapy against solid tumors
      Using genetically engineered preclinical models to study T cell...
      Immune checkpoint therapy (ICT) is a front-line treatment for lung cancer; however, low mutational burden and ‘non-T cell inflamed’ signatures predict poor responses to ICT in ~5...
      Speaker: Leah Schmidt, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2021
      3
      MAY 11, 2021 | 8:00 AM
      Miltenyi's World of T cells - Solutions to enhance your T cell experiments
      Miltenyi's World of T cells - Solutions to enhance your T cell...
      DATE: May 11, 2021 TIME: 8:00am PDT T cells are most important from basic research to therapeutic approaches and play a pivotal role in many diverse application fields such as basic immu...
      Speaker: Dr. Marcello Stein
      Sponsored By: Miltenyi Biotec
      9
      APR 21, 2021 | 12:00 AM
      Past, Present and Future of Engineered Cell Therapy
      Past, Present and Future of Engineered Cell Therapy
      Engineered cell therapy is an emerging field of science to target and treat cancer. Current strategies include utilizing immune cells such as T cells, NK cells and Macrophages or other cells...
      Speaker: Janani Krishnamurthy, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      2
      APR 20, 2021 | 5:00 PM
      Researchers share their Spatial Discoveries in Cancer Research
      Researchers share their Spatial Discoveries in Cancer Research
      Date: April 20, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers on Oncology - Professor Joan Seoane Prof. Joan Seoane, Group Leader and Director of the Translational Re...
      Speaker: Noel De Miranda , Vasilis Stavrinides, MD
      Sponsored By: NanoString Technologies, Illumina
      4
      APR 08, 2021 | 5:00 PM
      Generating multi-omics atlas of CD8+ T cell exhaustion vs. dysfunctional states in immuno-oncology
      Generating multi-omics atlas of CD8+ T cell exhaustion vs. dysfunctional...
      DATE: April 08, 2021 TIME: 08:00am PDT Multi-omics involves the use of different data modalities to study multiple “omes”, such as the genome, transcriptome, epigenome, and/or t...
      Speaker: Prof. Abhishek Garg , Dr. Maria Vallejo
      Sponsored By: Miltenyi Biotec
      8
      MAR 16, 2021 | 8:00 AM
      The latest developments for enriching and analyzing antigen- and virus-specific T cells
      The latest developments for enriching and analyzing antigen- and...
      DATE: March 09, 2021 TIME: 08:00am PST The COVID-19 pandemic has placed urgency on precise analysis of rare antigen- and virus-specific T cells. At Miltenyi Biotec, we offer a complete workf...
      Speaker: Lorenz Fülle, PhD
      Sponsored By: Miltenyi Biotec
      12
      FEB 03, 2021 | 8:00 AM
      An introduction to immuno-oncology at Miltenyi Biotec
      An introduction to immuno-oncology at Miltenyi Biotec
      Date: February 3, 2021 Time: 8:00am (PST), 11:00am (EST) This introduction webinar will provide you with an overview of the general immuno-oncology (IO) research field...
      Speaker: Dr. Marcello Stein
      Sponsored By: Miltenyi Biotec
      19 2
      JAN 19, 2021 | 8:00 AM
      The inhibitory role of specific macrophages in RCC
      The inhibitory role of specific macrophages in RCC
      Date: January 19, 2021 Time: 8:00am (PST), 11:00am (EST) Only a small subset of patients with clear cell Renal Cell Carcinoma (ccRCC) respond to immunotherapy with checkpoint inhibitors. Res...
      Speaker: Dr. Elfriede Nößner
      Sponsored By: Visiopharm®
      9
      OCT 08, 2020 | 3:00 PM
      Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
      Reducing biological variance in tumor-antigen expression to standardize...
      The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
      Speaker: Benjamin Borgo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      SEP 23, 2020 | 12:00 PM
      Mass Cytometry in Translational Research: Session II
      Mass Cytometry in Translational Research: Session II
      B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...
      Speaker: Handan Xiang, PhD , Pei-Yu Chen, PhD , Hiranmayi Ravichandran, MS , Rafet Basar, MD , Amir Horowitz, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      SEP 09, 2020 | 12:00 AM
      Leveraging SMRT sequencing to resolve complex immune loci
      Leveraging SMRT sequencing to resolve complex immune loci
      The regions of our genome responsible for encoding the genes that regulate our immune response are some of the most complex and polymorphic known. This complexity encompasses multiple types...
      Speaker: Melissa L. Smith, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      JUL 29, 2020 | 5:00 PM
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
      Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 9:00 AM
      Impedance-based assay to evaluate potency of immunotherapy products
      Impedance-based assay to evaluate potency of immunotherapy products
      Advances in genetic engineering have improved specificity, safety and potency of T-cell receptor (TCR) and Chimeric Antigen Receptor (CAR-T) based therapies for solid and non-solid tumours....
      Speaker: Juan Miguel Sanchez Nieto, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 12:00 AM
      Modeling anti-tumor function of human T cells
      Modeling anti-tumor function of human T cells
      Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
      Speaker: Michael Overstreet, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 07, 2020 | 7:30 AM
      Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
      Deciphering T cell heterogeneity in humans through analysis of...
      In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely uniq...
      Speaker: Evan Newell, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUN 17, 2020 | 3:00 PM
      COVID-19: Enrichment and analysis of rare antigen- and virus-specific T cells
      COVID-19: Enrichment and analysis of rare antigen- and virus-specific...
      Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious diseases, immuno-oncology, as well...
      Speaker: Dr. Marcello Stein
      Presented at: Coronavirus Series
      Sponsored By: Miltenyi Biotec
      1
      JUN 17, 2020 | 7:30 AM
      Development of Luminex Based Serological Test for COVID-19 Diagnosis and Monitoring
      Development of Luminex Based Serological Test for COVID-19 Diagnosis...
      Coronavirus disease 2019 (Covid-19) is a global pandemic that has impacted the lives of the entire world’s population. Accurate and effective testing mechanisms to identify those with...
      Speaker: Imad Tarhoni, MD, PhD
      Presented at: Coronavirus Series
      Sponsored By: Luminex - A DiaSorin Company
      2
      JUN 03, 2020 | 12:00 PM
      Single cell multiomic analysis of T-cell exhaustion
      Single cell multiomic analysis of T-cell exhaustion
      A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
      Speaker: Pratip K. Chattopadhyay
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: BD
      2
      JUN 03, 2020 | 12:00 AM
      Checkpoint blockade-induced autoimmunity: Lessons from mouse models of type 1 diabetes
      Checkpoint blockade-induced autoimmunity: Lessons from mouse models...
      Programmed death-1 (PD-1) inhibits T and B cell function upon ligand binding. PD-1 blockade revolutionized cancer treatment, and while numerous patients respond, some develop autoimmune-like...
      Speaker: Tijana Martinov, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      2
      MAY 27, 2020 | 9:00 AM
      Enrichment & analysis of rare antigen & virus-specific T cells
      Enrichment & analysis of rare antigen & virus-specific T cells
      DATE: May 27, 2020 TIME: 9:00am PT Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious...
      Speaker: Marcello Stein, PhD.
      Sponsored By: Miltenyi Biotec
      20
      MAY 20, 2020 | 12:45 PM
      Molecular and Immunologic Profiling of CD8+ T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
      Molecular and Immunologic Profiling of CD8+ T Cell Responses in...
      Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
      Speaker: Juraj Adamik, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
    JUN 02, 2021 | 12:00 AM
    Engineering universal chimeric antigen receptors (CARs) for cancer therapy
    Engineering universal chimeric antigen receptors (CARs) for cancer...
    Learning Objectives: 1. Define “universal CARs” and describe their mechanism of action. 2. Explain current challenges in CAR T cell therapy. 3. Describe potential benefits and ch...
    Speaker: Jason Lohmueller, Ph.D.
    Presented at: Immuno-Oncology Virtual Event Series 2021
    2
    JUN 02, 2021 | 12:00 AM
    EZH2 as an Actionable Therapeutic Target to Enhance Anti-Tumor Immune Response In Prostate Cancer
    EZH2 as an Actionable Therapeutic Target to Enhance Anti-Tumor...
    Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
    Speaker: Leigh Ellis, Ph.D.
    Presented at: Immuno-Oncology Virtual Event Series 2021
    1
    JUN 02, 2021 | 12:00 AM
    Development of FGFR4 targeted Chimeric Antigen Receptors (CARs) for treatment of Rhabdomyosarcoma
    Development of FGFR4 targeted Chimeric Antigen Receptors (CARs)...
    Rhabdomyosarcoma (RMS) is a soft tissue cancer commonly arising in muscle and is the most common soft tissue cancer in children. Patients with metastatic RMS have a poor prognosis that has n...
    Speaker: Peter Sullivan, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2021
    1
    JUN 02, 2021 | 12:00 AM
    Using genetically engineered preclinical models to study T cell therapy against solid tumors
    Using genetically engineered preclinical models to study T cell...
    Immune checkpoint therapy (ICT) is a front-line treatment for lung cancer; however, low mutational burden and ‘non-T cell inflamed’ signatures predict poor responses to ICT in ~5...
    Speaker: Leah Schmidt, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2021
    3
    MAY 11, 2021 | 8:00 AM
    Miltenyi's World of T cells - Solutions to enhance your T cell experiments
    Miltenyi's World of T cells - Solutions to enhance your T cell...
    DATE: May 11, 2021 TIME: 8:00am PDT T cells are most important from basic research to therapeutic approaches and play a pivotal role in many diverse application fields such as basic immu...
    Speaker: Dr. Marcello Stein
    Sponsored By: Miltenyi Biotec
    9
     
     
  • APR 21, 2021 | 12:00 AM
    Past, Present and Future of Engineered Cell Therapy
    Past, Present and Future of Engineered Cell Therapy
    Engineered cell therapy is an emerging field of science to target and treat cancer. Current strategies include utilizing immune cells such as T cells, NK cells and Macrophages or other cells...
    Speaker: Janani Krishnamurthy, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    2
    APR 20, 2021 | 5:00 PM
    Researchers share their Spatial Discoveries in Cancer Research
    Researchers share their Spatial Discoveries in Cancer Research
    Date: April 20, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers on Oncology - Professor Joan Seoane Prof. Joan Seoane, Group Leader and Director of the Translational Re...
    Speaker: Noel De Miranda , Vasilis Stavrinides, MD
    Sponsored By: NanoString Technologies, Illumina
    4
    APR 08, 2021 | 5:00 PM
    Generating multi-omics atlas of CD8+ T cell exhaustion vs. dysfunctional states in immuno-oncology
    Generating multi-omics atlas of CD8+ T cell exhaustion vs. dysfunctional...
    DATE: April 08, 2021 TIME: 08:00am PDT Multi-omics involves the use of different data modalities to study multiple “omes”, such as the genome, transcriptome, epigenome, and/or t...
    Speaker: Prof. Abhishek Garg , Dr. Maria Vallejo
    Sponsored By: Miltenyi Biotec
    8
    MAR 16, 2021 | 8:00 AM
    The latest developments for enriching and analyzing antigen- and virus-specific T cells
    The latest developments for enriching and analyzing antigen- and...
    DATE: March 09, 2021 TIME: 08:00am PST The COVID-19 pandemic has placed urgency on precise analysis of rare antigen- and virus-specific T cells. At Miltenyi Biotec, we offer a complete workf...
    Speaker: Lorenz Fülle, PhD
    Sponsored By: Miltenyi Biotec
    12
    FEB 03, 2021 | 8:00 AM
    An introduction to immuno-oncology at Miltenyi Biotec
    An introduction to immuno-oncology at Miltenyi Biotec
    Date: February 3, 2021 Time: 8:00am (PST), 11:00am (EST) This introduction webinar will provide you with an overview of the general immuno-oncology (IO) research field...
    Speaker: Dr. Marcello Stein
    Sponsored By: Miltenyi Biotec
    19 2
     
     
  • JAN 19, 2021 | 8:00 AM
    The inhibitory role of specific macrophages in RCC
    The inhibitory role of specific macrophages in RCC
    Date: January 19, 2021 Time: 8:00am (PST), 11:00am (EST) Only a small subset of patients with clear cell Renal Cell Carcinoma (ccRCC) respond to immunotherapy with checkpoint inhibitors. Res...
    Speaker: Dr. Elfriede Nößner
    Sponsored By: Visiopharm®
    9
    OCT 08, 2020 | 3:00 PM
    Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
    Reducing biological variance in tumor-antigen expression to standardize...
    The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
    Speaker: Benjamin Borgo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
    SEP 23, 2020 | 12:00 PM
    Mass Cytometry in Translational Research: Session II
    Mass Cytometry in Translational Research: Session II
    B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...
    Speaker: Handan Xiang, PhD , Pei-Yu Chen, PhD , Hiranmayi Ravichandran, MS , Rafet Basar, MD , Amir Horowitz, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
    SEP 09, 2020 | 12:00 AM
    Leveraging SMRT sequencing to resolve complex immune loci
    Leveraging SMRT sequencing to resolve complex immune loci
    The regions of our genome responsible for encoding the genes that regulate our immune response are some of the most complex and polymorphic known. This complexity encompasses multiple types...
    Speaker: Melissa L. Smith, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    JUL 29, 2020 | 5:00 PM
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
    Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
     
     
  • JUL 29, 2020 | 9:00 AM
    Impedance-based assay to evaluate potency of immunotherapy products
    Impedance-based assay to evaluate potency of immunotherapy products
    Advances in genetic engineering have improved specificity, safety and potency of T-cell receptor (TCR) and Chimeric Antigen Receptor (CAR-T) based therapies for solid and non-solid tumours....
    Speaker: Juan Miguel Sanchez Nieto, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 12:00 AM
    Modeling anti-tumor function of human T cells
    Modeling anti-tumor function of human T cells
    Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
    Speaker: Michael Overstreet, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 07, 2020 | 7:30 AM
    Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
    Deciphering T cell heterogeneity in humans through analysis of...
    In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely uniq...
    Speaker: Evan Newell, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUN 17, 2020 | 3:00 PM
    COVID-19: Enrichment and analysis of rare antigen- and virus-specific T cells
    COVID-19: Enrichment and analysis of rare antigen- and virus-specific...
    Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious diseases, immuno-oncology, as well...
    Speaker: Dr. Marcello Stein
    Presented at: Coronavirus Series
    Sponsored By: Miltenyi Biotec
    1
    JUN 17, 2020 | 7:30 AM
    Development of Luminex Based Serological Test for COVID-19 Diagnosis and Monitoring
    Development of Luminex Based Serological Test for COVID-19 Diagnosis...
    Coronavirus disease 2019 (Covid-19) is a global pandemic that has impacted the lives of the entire world’s population. Accurate and effective testing mechanisms to identify those with...
    Speaker: Imad Tarhoni, MD, PhD
    Presented at: Coronavirus Series
    Sponsored By: Luminex - A DiaSorin Company
    2
     
     
  • JUN 03, 2020 | 12:00 PM
    Single cell multiomic analysis of T-cell exhaustion
    Single cell multiomic analysis of T-cell exhaustion
    A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
    Speaker: Pratip K. Chattopadhyay
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: BD
    2
    JUN 03, 2020 | 12:00 AM
    Checkpoint blockade-induced autoimmunity: Lessons from mouse models of type 1 diabetes
    Checkpoint blockade-induced autoimmunity: Lessons from mouse models...
    Programmed death-1 (PD-1) inhibits T and B cell function upon ligand binding. PD-1 blockade revolutionized cancer treatment, and while numerous patients respond, some develop autoimmune-like...
    Speaker: Tijana Martinov, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    2
    MAY 27, 2020 | 9:00 AM
    Enrichment & analysis of rare antigen & virus-specific T cells
    Enrichment & analysis of rare antigen & virus-specific T cells
    DATE: May 27, 2020 TIME: 9:00am PT Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious...
    Speaker: Marcello Stein, PhD.
    Sponsored By: Miltenyi Biotec
    20
    MAY 20, 2020 | 12:45 PM
    Molecular and Immunologic Profiling of CD8+ T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
    Molecular and Immunologic Profiling of CD8+ T Cell Responses in...
    Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
    Speaker: Juraj Adamik, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
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