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    Antisense Oligonucleotide

    Antisense Oligonucleotide (ASO) is a synthetic polymer. It is a single-stranded deoxyribonucleotide, which is complementary to the mRNA target. Antisense oligonucleotides may be used to block the production of proteins needed for cell growth.

    Trending News

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      2
      APR 15, 2023
      Drug Discovery & Development
      Strand of RNA Shuts Down Deadly Pediatric Cancer
      Strand of RNA Shuts Down Deadly Pediatric Cancer
      The exact match for a mutant protein's mRNA, called an antisense oligonucleotide (ASO), stops cancerous protein producti ...
      Written By: Amielle Moreno
      4
      MAR 28, 2023
      Drug Discovery & Development
      FDA's advisory panel recommends approval for an "ultra-rare" ALS drug
      FDA's advisory panel recommends approval for an "ultra-rare" ALS drug
      Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is also known as Lou Gehrig’s Disease. It ...
      Written By: Greta Anne
      4
      MAR 02, 2023
      Cell & Molecular Biology
      Scientists Discover a Cell That Can Promote Blood Vessel Formation
      Scientists Discover a Cell That Can Promote Blood Vessel Formation
      Scientists have discovered a novel type of cell, called the vasculogenic fibroblast, which can be found in mice and huma ...
      Written By: Carmen Leitch
      2
      FEB 07, 2023
      Health & Medicine
      ALS Breakthrough: Two Targets Touted to Treat TDP-43 Trafficking Trouble
      ALS Breakthrough: Two Targets Touted to Treat TDP-43 Trafficking Trouble
      One lab drops two papers touting the clearance of protein aggregation in ALS
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      2
      AUG 09, 2022
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      An Inhaled COVID-19 Treatment Halts Viral Replication
      This new approach could also be effective against many different types of RNA viruses.
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      JUN 15, 2021
      Genetics & Genomics
      DNA May Soon Become a Digital Storage Device
      DNA May Soon Become a Digital Storage Device
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      APR 01, 2021
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      SEP 13, 2020
      Cell & Molecular Biology
      RNA Found on the Surface of Human Cells
      RNA Found on the Surface of Human Cells
      The surface of a cell carries many features to help it carry out its functions, communicate with other cells, gather inf ...
      Written By: Carmen Leitch
      3
      OCT 09, 2019
      Drug Discovery & Development
      Tailor-made Drug for Girl with Rare Genetic Disease
      Tailor-made Drug for Girl with Rare Genetic Disease
      Researchers have used personalized medicine to develop a tailor-made genetic treatment for a girl diagnosed with a rare ...
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      2
      SEP 25, 2019
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      JUL 09, 2019
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      OCT 30, 2018
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      JUL 17, 2018
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      Possible Therapeutic Drugs for Inherited Form of ALS
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      APR 11, 2018
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      NOV 05, 2017
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      New Drug 'Transformed' Infant Patients With Deadly Disorder
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      DEC 27, 2016
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      AUG 03, 2016
      Clinical & Molecular DX
      Gene Therapy for Spinal Muscular Atrophy Gains Traction
      Gene Therapy for Spinal Muscular Atrophy Gains Traction
      Gene therapy research for spinal muscular atrophy is seemingly on an onwards and upwards trajectory. In the last week, r ...
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      APR 19, 2016
      Health & Medicine
      Clever Tuberculosis Bacteria Have A Secret Hiding Place
      Clever Tuberculosis Bacteria Have A Secret Hiding Place
      Mycobacterium tuberculosis, the bacterial species behind tuberculosis infections, is the leading cause of bacterial deat ...
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      AUG 30, 2015
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      Cluttered Cellular Highways
      Johns Hopkins researchers think that a common gene mutation triggers the brain damage associated with both amyotrophic l ...
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      2
    SEP 17, 2025
    Genetics & Genomics
    Why This ALS Drug Was a Miss, Though it Hit the Target
    Why This ALS Drug Was a Miss, Though it Hit the Target
    Scientists have learned more about the effects of an experimental amyotrophic lateral sclerosis (ALS) drug candidate tha ...
    Written By: Carmen Leitch
    2
    APR 15, 2023
    Drug Discovery & Development
    Strand of RNA Shuts Down Deadly Pediatric Cancer
    Strand of RNA Shuts Down Deadly Pediatric Cancer
    The exact match for a mutant protein's mRNA, called an antisense oligonucleotide (ASO), stops cancerous protein producti ...
    Written By: Amielle Moreno
    4
    MAR 28, 2023
    Drug Discovery & Development
    FDA's advisory panel recommends approval for an "ultra-rare" ALS drug
    FDA's advisory panel recommends approval for an "ultra-rare" ALS drug
    Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is also known as Lou Gehrig’s Disease. It ...
    Written By: Greta Anne
    4
    MAR 02, 2023
    Cell & Molecular Biology
    Scientists Discover a Cell That Can Promote Blood Vessel Formation
    Scientists Discover a Cell That Can Promote Blood Vessel Formation
    Scientists have discovered a novel type of cell, called the vasculogenic fibroblast, which can be found in mice and huma ...
    Written By: Carmen Leitch
    2
    FEB 07, 2023
    Health & Medicine
    ALS Breakthrough: Two Targets Touted to Treat TDP-43 Trafficking Trouble
    ALS Breakthrough: Two Targets Touted to Treat TDP-43 Trafficking Trouble
    One lab drops two papers touting the clearance of protein aggregation in ALS
    Written By: Amielle Moreno
    2
     
     
  • AUG 09, 2022
    Microbiology
    An Inhaled COVID-19 Treatment Halts Viral Replication
    An Inhaled COVID-19 Treatment Halts Viral Replication
    This new approach could also be effective against many different types of RNA viruses.
    Written By: Carmen Leitch
    4
    JUN 15, 2021
    Genetics & Genomics
    DNA May Soon Become a Digital Storage Device
    DNA May Soon Become a Digital Storage Device
    We live in an age of information and data, and more is being generated every day. It's estimated that there are about te ...
    Written By: Carmen Leitch
    1
    APR 01, 2021
    Drug Discovery & Development
    Injection Treats Childhood Blindness
    Injection Treats Childhood Blindness
    A patient with a genetic-based childhood blindness has gained vision after receiving an experimental RNA therapeutic tre ...
    Written By: Nouran Amin
    1
    SEP 13, 2020
    Cell & Molecular Biology
    RNA Found on the Surface of Human Cells
    RNA Found on the Surface of Human Cells
    The surface of a cell carries many features to help it carry out its functions, communicate with other cells, gather inf ...
    Written By: Carmen Leitch
    3
    OCT 09, 2019
    Drug Discovery & Development
    Tailor-made Drug for Girl with Rare Genetic Disease
    Tailor-made Drug for Girl with Rare Genetic Disease
    Researchers have used personalized medicine to develop a tailor-made genetic treatment for a girl diagnosed with a rare ...
    Written By: Annie Lennon
    2
     
     
  • SEP 25, 2019
    Genetics & Genomics
    A DNA 'Stitch' as a Therapy for Duchenne Muscular Dystrophy
    A DNA 'Stitch' as a Therapy for Duchenne Muscular Dystrophy
    DMD is a genetic disorder that causes degeneration in muscles. Now there may be a treatment for as many as 47% of patien ...
    Written By: Carmen Leitch
    1
    JUL 09, 2019
    Cancer
    An Ointment to Stop Skin Cancer Growth
    An Ointment to Stop Skin Cancer Growth
    Russian scientists are developing an ointment to undermine the growth of skin cancer, according to a review recently pub ...
    Written By: Julia Travers
    1
    OCT 30, 2018
    Drug Discovery & Development
    Re-sensitizing Drug-resistant Human Tumor Cells
    Re-sensitizing Drug-resistant Human Tumor Cells
    Understanding how cancer cells avoid death despite their DNA being damaged will create new strategies to enhance cancer ...
    Written By: Nouran Amin
    2
    JUL 17, 2018
    Drug Discovery & Development
    Possible Therapeutic Drugs for Inherited Form of ALS
    Possible Therapeutic Drugs for Inherited Form of ALS
    Roughly 20,000 people in the United States are diagnosed with Lou Gehrig’s Disease, better known as amyotrophic la ...
    Written By: Nouran Amin
    2
    APR 11, 2018
    Videos
    Treating ALS by Stopping Faulty Proteins
    Treating ALS by Stopping Faulty Proteins
    Neurodegenerative disorders are diseases that cause a progressive loss of nerve cells; that can result in devastating pr ...
    Written By: Carmen Leitch
    2
     
     
  • NOV 05, 2017
    Cell & Molecular Biology
    New Drug 'Transformed' Infant Patients With Deadly Disorder
    New Drug 'Transformed' Infant Patients With Deadly Disorder
    Nusinersen may be a life-changer for patients with spinal muscular atrophy (SMA) type 1.
    Written By: Carmen Leitch
    1
    DEC 27, 2016
    Chemistry & Physics
    Improving Health in Obese and Diabetic Patients Using Protein Silencing
    Improving Health in Obese and Diabetic Patients Using Protein Silencing
    Obesity is a common epidemic worldwide, but scientists are now bringing to light an associated health issue, fatty liver ...
    Written By: Jennifer Ellis
    3
    AUG 03, 2016
    Clinical & Molecular DX
    Gene Therapy for Spinal Muscular Atrophy Gains Traction
    Gene Therapy for Spinal Muscular Atrophy Gains Traction
    Gene therapy research for spinal muscular atrophy is seemingly on an onwards and upwards trajectory. In the last week, r ...
    Written By: Xuan Pham
    2
    APR 19, 2016
    Health & Medicine
    Clever Tuberculosis Bacteria Have A Secret Hiding Place
    Clever Tuberculosis Bacteria Have A Secret Hiding Place
    Mycobacterium tuberculosis, the bacterial species behind tuberculosis infections, is the leading cause of bacterial deat ...
    Written By: Kara Marker
    2
    AUG 30, 2015
    Neuroscience
    Cluttered Cellular Highways
    Cluttered Cellular Highways
    Johns Hopkins researchers think that a common gene mutation triggers the brain damage associated with both amyotrophic l ...
    Written By: Ilene Schneider
    2
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