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    Cancer genetics and genomics

    Cancer genetics and genomics is the study of how our genetic profiles are linked to the onset or progression of malignancies. Mutations leading to cancer can be inherited or acquired (also called somatic). Cancer genetics and genomic studies evaluate how such mutations relate to cancer. Additionally, genetic and genomic studies can determine how an individual will respond to therapy and may help determine the best course of treatment for cancer.

    Webinars

    • MAY 09, 2019 | 10:30 AM
      Background and Troubleshooting for RT-PCR
      Background and Troubleshooting for RT-PCR
      Real-time PCR, or quantitative qPCR, is a commonly used molecular biology lab technique to determine the actual amount of PCR product at a given cycle. For quantitative reverse transcription...
      Speaker: Gillian Browne, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: MilliporeSigma
      4
      MAY 09, 2019 | 9:00 AM
      Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank Information
      Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank...
      The advent of precision medicine largely depends on the creation of precise and accurate predictive tools. While most late-onset diseases are moderately to highly heritable, using genetic inf...
      Speaker: Guillaume Paré, MD, MSc, FRCPC
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: Illumina
      2 1
      MAY 09, 2019 | 6:00 AM
      AI-Driven Literature Curation for Determining Genomic Variant Pathogenicity
      AI-Driven Literature Curation for Determining Genomic Variant...
      Variant interpretation presents a bottleneck for many labs, posing a challenge to the broader adoption of precision medicine. The ACMG/AMP variant classification framework has provided a foun...
      Speaker: Mark Kiel, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      4
      MAY 08, 2019 | 10:30 AM
      C.E. CREDITS
      Using Networks to Understand Cancer Risk
      Using Networks to Understand Cancer Risk
      One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAY 08, 2019 | 10:30 AM
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
      The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
      Speaker: Devendra Mistry, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      MAY 08, 2019 | 6:00 AM
      C.E. CREDITS
      Novel DNA Methylation in Mammals
      Novel DNA Methylation in Mammals
      Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
      Speaker: Tao Wu, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      APR 25, 2019 | 6:00 AM
      Long-Read Sequencing and Infectious Disease: New Insights Into Longstanding Challenges
      Long-Read Sequencing and Infectious Disease: New Insights Into...
      To reduce the global burden diseases causes by infectious disease, including parasites and bacteria, scientists need better information about mechanisms of virulence, immune evasion, and drug...
      Speaker: Meredith Ashby, PhD
      Presented at: Infectious Disease Virtual Event Series 2019
      Sponsored By: PacBio
      2
      APR 10, 2019 | 1:30 PM
      Tools & Processes for Making Evidence-Based Policy Decisions
      Tools & Processes for Making Evidence-Based Policy Decisions
      The exponential advents of advances in techniques and types of molecular diagnostic testing, and modifying strategies for these tests, are encouraging; but these evolutions simultaneously con...
      Speaker: Eugean Jiwanmall, MPH, MBA
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      3
      APR 10, 2019 | 1:30 PM
      Detection and Interpretation of Complex Myeloid Leukemia Mutations
      Detection and Interpretation of Complex Myeloid Leukemia Mutations
      Myeloid leukemias encompass a group of different diseases that include myeloproliferative neoplasms (MPN), myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). These diseases are d...
      Speaker: Véronique Laloux, PhD , Beate Litzenburger, Ph.D.
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: QIAGEN
      6
      APR 10, 2019 | 1:30 PM
      Laboratory Medicine Beyond The Box: Value Based Health Care & Diagnostic Evidence
      Laboratory Medicine Beyond The Box: Value Based Health Care &...
      Integration of technology is influencing practice in the clinical laboratory and treatment of patients in the clinical practice arena. As laboratories begin to move from a volume to value mod...
      Speaker: Elizabeth Marlowe, PhD, D(ABMM) , Joanna Sickler, MPH, MBA
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
      APR 10, 2019 | 12:00 PM
      Digital Biosensors and the Internet of Biology
      Digital Biosensors and the Internet of Biology
      The prevailing philosophy in biological testing has been to focus on simple tests with easy to interpret information such as ELISA or lateral flow assays. At the same time, there has been a d...
      Speaker: Brett Goldsmith, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
      APR 10, 2019 | 12:00 PM
      Best Practices for Implementing NGS and Positioning for Future Growth: Perspectives from 2 Labs
      Best Practices for Implementing NGS and Positioning for Future...
      Personalized medicine driven by genomic-based treatments continues to increase in importance. Representatives from two distinct healthcare entities – a regional reference lab and commun...
      Speaker: Tony Magliocco, MD , Keith Gligorich, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: Illumina
      7
      APR 10, 2019 | 12:00 PM
      Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
      Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
      Determining which patients would derive clinical benefit from immunotherapy is a compelling clinical question. Biomarkers have been shown to predict therapy outcome in various types of cancer...
      Speaker: Shidong Jia, MD, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
      APR 10, 2019 | 10:30 AM
      CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/Cas9 Immobilized on a Graphene Biosensors
      CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/Cas9...
      CRISPR-chip combines two powerful technologies ,CRISPR and Graphene, for rapid detection of nucleic acids. This talk will focus on design and fabrication of CRISPR-chip and its potential util...
      Speaker: Kiana Aran, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
      APR 10, 2019 | 10:30 AM
      Better Knowledge, Better Care: Precision Medicine for Any Cancer, Any Assay, on Your Platform
      Better Knowledge, Better Care: Precision Medicine for Any Cancer,...
      QIAGEN helps your team focus on the opportunities, not the obstacles, with an end-to-end clinical testing solution. During this talk, we will present our clinical decision support solutions,...
      Speaker: Sheryl Elkin, PhD , Dan Richards, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: QIAGEN
      2
      APR 10, 2019 | 10:30 AM
      A Sample to Insight Solution for Detection and Classification of Challenging Pathogenic BRCA Mutations
      A Sample to Insight Solution for Detection and Classification...
      The BRCA1 and BRCA2 genes represent the best examples of the modern understanding of cancer molecular genetics. Testing for germline and somatic mutations in BRCA 1/2 has gradually become com...
      Speaker: Anika Joecker, PhD , Jennifer Poitras, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: QIAGEN
      5
      APR 10, 2019 | 9:00 AM
      CRISPR Proteins: Enabling the Next-Generation of Molecular Diagnostics
      CRISPR Proteins: Enabling the Next-Generation of Molecular Diagnostics
      Mammoth Biosciences is developing next-generation CRISPR platforms to build rapid, point-of-care molecular diagnostics. Our innovative DETECTR technology leverages novel CRISPR proteins whose...
      Speaker: James Broughton
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      5
      APR 10, 2019 | 9:00 AM
      Validation and Implementation of Quantitative Molecular Assays
      Validation and Implementation of Quantitative Molecular Assays
      Regulatory requirements for verification and validation are complex and often cause confusion among clinical laboratorians, especially in regards to quantitative molecular assays. This presen...
      Speaker: Morgan Pence, PhD, D(ABMM)
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: Diasorin
      8
      APR 10, 2019 | 9:00 AM
      Novel Applications of Molecular Diagnostics in Infectious Diseases
      Novel Applications of Molecular Diagnostics in Infectious Diseases
      The laboratory diagnosis of infectious diseases has traditionally relied on recovery of pathogens in cultures and for many infections, this approach remains the standard of care. The developm...
      Speaker: Esther Babady, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      7
      APR 10, 2019 | 7:30 AM
      Keynote Presentation: Clinical Lab 2.0 - How Laboratories Can Thrive in a Value Based Care System
      Keynote Presentation: Clinical Lab 2.0 - How Laboratories Can...
      As reimbursement changes and healthcare moves towards value-based models, the clinical laboratory is faced with the challenge of redefining its value outside the cost per test. This session...
      Speaker: Michael Crossey, MD, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      3
      APR 10, 2019 | 6:00 AM
      Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
      Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
      Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      6
      APR 10, 2019 | 6:00 AM
      Bio-Rad Unity as a Solution for Molecular Quality Control Data Management
      Bio-Rad Unity as a Solution for Molecular Quality Control Data...
      Management of complex quality control (QC) data is essential to insure high quality patient care and maintain regulatory compliance within clinical laboratories. Robust software solutions fo...
      Speaker: Duane Newton, PhD, D(ABMM), FIDSA
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: Bio-Rad Laboratories
      10
      MAR 28, 2019 | 12:00 PM
      Cannabis is Personal! Learn How Your Genetics Play a Big Roll
      Cannabis is Personal! Learn How Your Genetics Play a Big Roll
      In 2018 with more and more consumers having access to legal Cannabis the interest in incorporating cannabis in to their lifestyles is becoming more and more prevalent. Len May, founder of End...
      Speaker: Len May, MSC
      Presented at: Cannabis Sciences Virtual Event Series 2019
      2
      MAR 21, 2019 | 7:00 AM
      Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
      Phenotyping the tumor micro-environment with advanced tissue-based...
      DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
      Speaker: Katir Patel, PhD
      Sponsored By: Ultivue
      11
    MAY 09, 2019 | 10:30 AM
    Background and Troubleshooting for RT-PCR
    Background and Troubleshooting for RT-PCR
    Real-time PCR, or quantitative qPCR, is a commonly used molecular biology lab technique to determine the actual amount of PCR product at a given cycle. For quantitative reverse transcription...
    Speaker: Gillian Browne, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: MilliporeSigma
    4
    MAY 09, 2019 | 9:00 AM
    Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank Information
    Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank...
    The advent of precision medicine largely depends on the creation of precise and accurate predictive tools. While most late-onset diseases are moderately to highly heritable, using genetic inf...
    Speaker: Guillaume Paré, MD, MSc, FRCPC
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: Illumina
    2 1
    MAY 09, 2019 | 6:00 AM
    AI-Driven Literature Curation for Determining Genomic Variant Pathogenicity
    AI-Driven Literature Curation for Determining Genomic Variant...
    Variant interpretation presents a bottleneck for many labs, posing a challenge to the broader adoption of precision medicine. The ACMG/AMP variant classification framework has provided a foun...
    Speaker: Mark Kiel, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    4
    MAY 08, 2019 | 10:30 AM
    C.E. CREDITS
    Using Networks to Understand Cancer Risk
    Using Networks to Understand Cancer Risk
    One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAY 08, 2019 | 10:30 AM
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
    The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
    Speaker: Devendra Mistry, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
     
     
  • MAY 08, 2019 | 6:00 AM
    C.E. CREDITS
    Novel DNA Methylation in Mammals
    Novel DNA Methylation in Mammals
    Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
    Speaker: Tao Wu, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    APR 25, 2019 | 6:00 AM
    Long-Read Sequencing and Infectious Disease: New Insights Into Longstanding Challenges
    Long-Read Sequencing and Infectious Disease: New Insights Into...
    To reduce the global burden diseases causes by infectious disease, including parasites and bacteria, scientists need better information about mechanisms of virulence, immune evasion, and drug...
    Speaker: Meredith Ashby, PhD
    Presented at: Infectious Disease Virtual Event Series 2019
    Sponsored By: PacBio
    2
    APR 10, 2019 | 1:30 PM
    Tools & Processes for Making Evidence-Based Policy Decisions
    Tools & Processes for Making Evidence-Based Policy Decisions
    The exponential advents of advances in techniques and types of molecular diagnostic testing, and modifying strategies for these tests, are encouraging; but these evolutions simultaneously con...
    Speaker: Eugean Jiwanmall, MPH, MBA
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    3
    APR 10, 2019 | 1:30 PM
    Detection and Interpretation of Complex Myeloid Leukemia Mutations
    Detection and Interpretation of Complex Myeloid Leukemia Mutations
    Myeloid leukemias encompass a group of different diseases that include myeloproliferative neoplasms (MPN), myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). These diseases are d...
    Speaker: Véronique Laloux, PhD , Beate Litzenburger, Ph.D.
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: QIAGEN
    6
    APR 10, 2019 | 1:30 PM
    Laboratory Medicine Beyond The Box: Value Based Health Care & Diagnostic Evidence
    Laboratory Medicine Beyond The Box: Value Based Health Care &...
    Integration of technology is influencing practice in the clinical laboratory and treatment of patients in the clinical practice arena. As laboratories begin to move from a volume to value mod...
    Speaker: Elizabeth Marlowe, PhD, D(ABMM) , Joanna Sickler, MPH, MBA
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
     
     
  • APR 10, 2019 | 12:00 PM
    Digital Biosensors and the Internet of Biology
    Digital Biosensors and the Internet of Biology
    The prevailing philosophy in biological testing has been to focus on simple tests with easy to interpret information such as ELISA or lateral flow assays. At the same time, there has been a d...
    Speaker: Brett Goldsmith, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
    APR 10, 2019 | 12:00 PM
    Best Practices for Implementing NGS and Positioning for Future Growth: Perspectives from 2 Labs
    Best Practices for Implementing NGS and Positioning for Future...
    Personalized medicine driven by genomic-based treatments continues to increase in importance. Representatives from two distinct healthcare entities – a regional reference lab and commun...
    Speaker: Tony Magliocco, MD , Keith Gligorich, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: Illumina
    7
    APR 10, 2019 | 12:00 PM
    Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
    Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
    Determining which patients would derive clinical benefit from immunotherapy is a compelling clinical question. Biomarkers have been shown to predict therapy outcome in various types of cancer...
    Speaker: Shidong Jia, MD, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
    APR 10, 2019 | 10:30 AM
    CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/Cas9 Immobilized on a Graphene Biosensors
    CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/Cas9...
    CRISPR-chip combines two powerful technologies ,CRISPR and Graphene, for rapid detection of nucleic acids. This talk will focus on design and fabrication of CRISPR-chip and its potential util...
    Speaker: Kiana Aran, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
    APR 10, 2019 | 10:30 AM
    Better Knowledge, Better Care: Precision Medicine for Any Cancer, Any Assay, on Your Platform
    Better Knowledge, Better Care: Precision Medicine for Any Cancer,...
    QIAGEN helps your team focus on the opportunities, not the obstacles, with an end-to-end clinical testing solution. During this talk, we will present our clinical decision support solutions,...
    Speaker: Sheryl Elkin, PhD , Dan Richards, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: QIAGEN
    2
     
     
  • APR 10, 2019 | 10:30 AM
    A Sample to Insight Solution for Detection and Classification of Challenging Pathogenic BRCA Mutations
    A Sample to Insight Solution for Detection and Classification...
    The BRCA1 and BRCA2 genes represent the best examples of the modern understanding of cancer molecular genetics. Testing for germline and somatic mutations in BRCA 1/2 has gradually become com...
    Speaker: Anika Joecker, PhD , Jennifer Poitras, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: QIAGEN
    5
    APR 10, 2019 | 9:00 AM
    CRISPR Proteins: Enabling the Next-Generation of Molecular Diagnostics
    CRISPR Proteins: Enabling the Next-Generation of Molecular Diagnostics
    Mammoth Biosciences is developing next-generation CRISPR platforms to build rapid, point-of-care molecular diagnostics. Our innovative DETECTR technology leverages novel CRISPR proteins whose...
    Speaker: James Broughton
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    5
    APR 10, 2019 | 9:00 AM
    Validation and Implementation of Quantitative Molecular Assays
    Validation and Implementation of Quantitative Molecular Assays
    Regulatory requirements for verification and validation are complex and often cause confusion among clinical laboratorians, especially in regards to quantitative molecular assays. This presen...
    Speaker: Morgan Pence, PhD, D(ABMM)
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: Diasorin
    8
    APR 10, 2019 | 9:00 AM
    Novel Applications of Molecular Diagnostics in Infectious Diseases
    Novel Applications of Molecular Diagnostics in Infectious Diseases
    The laboratory diagnosis of infectious diseases has traditionally relied on recovery of pathogens in cultures and for many infections, this approach remains the standard of care. The developm...
    Speaker: Esther Babady, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    7
    APR 10, 2019 | 7:30 AM
    Keynote Presentation: Clinical Lab 2.0 - How Laboratories Can Thrive in a Value Based Care System
    Keynote Presentation: Clinical Lab 2.0 - How Laboratories Can...
    As reimbursement changes and healthcare moves towards value-based models, the clinical laboratory is faced with the challenge of redefining its value outside the cost per test. This session...
    Speaker: Michael Crossey, MD, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    3
     
     
  • APR 10, 2019 | 6:00 AM
    Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
    Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
    Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    6
    APR 10, 2019 | 6:00 AM
    Bio-Rad Unity as a Solution for Molecular Quality Control Data Management
    Bio-Rad Unity as a Solution for Molecular Quality Control Data...
    Management of complex quality control (QC) data is essential to insure high quality patient care and maintain regulatory compliance within clinical laboratories. Robust software solutions fo...
    Speaker: Duane Newton, PhD, D(ABMM), FIDSA
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: Bio-Rad Laboratories
    10
    MAR 28, 2019 | 12:00 PM
    Cannabis is Personal! Learn How Your Genetics Play a Big Roll
    Cannabis is Personal! Learn How Your Genetics Play a Big Roll
    In 2018 with more and more consumers having access to legal Cannabis the interest in incorporating cannabis in to their lifestyles is becoming more and more prevalent. Len May, founder of End...
    Speaker: Len May, MSC
    Presented at: Cannabis Sciences Virtual Event Series 2019
    2
    MAR 21, 2019 | 7:00 AM
    Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
    Phenotyping the tumor micro-environment with advanced tissue-based...
    DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
    Speaker: Katir Patel, PhD
    Sponsored By: Ultivue
    11
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