Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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The complexity and heterogeneity of protein therapeutics present significant challenges in biologics discovery, as post-translational modifications (PTMs) and sequence variants can affect pr...
Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) is a powerful technique for studying protein dynamics, however its widespread application has been constrained by high sample consumpti...
At Evotec, we turn great science into real-world medicines; faster, smarter and at exceptional quality. We partner with biotech, pharma and academic institutions to deliver from disease unde...
The next leap in oncology therapeutics demands speed, precision, and rapid molecular innovation — and AI-driven antibody design (AIDD) is beginning to deliver. In this talk, we will un...
AUG 12, 2025 | 7:00 AM
C.E. CREDITS
Increasing the complexity of in vitro cell cultures to better model the in vivo environment is a growing focus in drug discovery and mechanistic research. It is well established that cells c...
Cell painting has established itself as a powerful tool for high content imaging, able to generate vast quantities of data in response to chemical perturbations. Over the past decade, cell p...
Biomarkers are no longer just exploratory tools-they're becoming strategic assets in drug development and clinical trials. Join a panel of industry thought leaders as they explore how biomar...
Bispecific antibodies (bsAbs) represent a versatile and increasingly important class of targeted therapeutics, designed to bind two distinct sites — either two different epitopes on th...
Join us for an in-depth webinar on quantitative chemoproteomics with TMT reagents, featuring two distinguished speakers from both academia and industry. This webinar aims to bridge the gap b...
The design, make, test, and analyze cycle (DMTA), which drives early-stage drug discovery, requires workflows and automated methods for sample storage and tracking, low volume dispensing of...
BrainXell offers the most comprehensive portfolio of high-purity iPSC-derived human neurons and glia, sourced from control, edited and disease lines, to advance translational research and dr...
Join us for a live webinar on the latest advancements in spatial biology. Featuring two insightful presentations, learn how cutting-edge imaging and single-cell technologies are transforming...
Join us for an enlightening session on the latest advancements in organoid research and drug discovery! Discover transformative applications, emerging trends, and common challenges in organo...
Using next-generation proteomics technologies, organoid-based research models have the potential to revolutionize drug discovery and personalized medicine, improving our understanding of neu...
At Thermo Fisher Scientific, our goal is to bring innovative new products and services that enable the development of more physiologically relevant disease models to help accelerate the drug...
Capturing membrane proteins in their native membrane nanodomain contexts Kallol Gupta, Ph.D. The intricate molecular environment of the native membrane profoundly influences every aspect of...
Stem cells, particularly Induced Pluripotent Stem Cells (iPSCs), are becoming essential tools in scientific research, from drug discovery to disease modeling. As the scientific community shi...
SEP 25, 2024 | 8:00 AM
C.E. CREDITS
Fluorescence microscopy offers robust, multi-parametric and scalable analysis of cell level activity in heterogenous populations with spatial and temporal resolution, often critical for effe...
One of the primary limitations in drug discovery and toxicology research is the lack of good model systems between the single cell level and animal or human systems. This is especially true...