Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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MAR 20, 2019Drug Discovery
MAR 20, 2019The U.S. Food and Drug Administration recently approved the first ever drug specifically for the treatment of postpartum depression a common and often deva...Written By: Nouran AminMAR 19, 2019Health & Medicine
MAR 19, 2019A pilot study suggests it might. Researchers at the University of Alabama, Birmingham, found that a low-carbohydrate diet was able to reduce pain intensity...Written By: Aleishia Harris-ArnoldMAR 18, 2019Cell & Molecular Biology
MAR 18, 2019Cystic fibrosis affects around 700,000 people worldwide. New research has found a potential treatment for patients that don't respond to current therapies....Written By: Carmen LeitchMAR 15, 2019Drug Discovery
MAR 15, 2019A virus-like particle vaccine was developed to stop chronic pain caused by osteoarthritis inhibiting a nerve growth factor (NGF). The vaccine was administe...Written By: Nouran AminMAR 14, 2019Cannabis Sciences
MAR 14, 2019Cirrhosis accounts for 31,000 deaths per year. Approximately 3.5 to 4.6 million people in the U.S. are chronically infected with the hepatitis C...Written By: Amy LoriauxMAR 13, 2019Drug Discovery
MAR 13, 2019The number of individuals diagnosed with liver cancer is on the rise and current therapies are largely ineffective. However, new preclinical data from the ...Written By: Nouran AminMAR 13, 2019Immunology
MAR 13, 2019Researchers have utilized cryo-electron microscopy to identify new cell membrane proteins...Written By: Nicholas BreehlMAR 13, 2019Cell & Molecular Biology
MAR 13, 2019An ever-increasing number of bacteria are able to evade the effects of antibiotics, which is considered a serious threat to public health....Written By: Carmen LeitchMAR 11, 2019Drug Discovery
MAR 11, 2019In a recent research study, precision cancer drugs called PARP inhibitors are previously known to boost the immune system were found to spark a powerful im...Written By: Nouran AminMAR 11, 2019Drug Discovery
MAR 11, 2019Many individuals going through depression gain little benefit from treatments whether drugs or talk therapy. Depression represents one of the greatest unme...Written By: Nouran AminMAR 10, 2019Drug Discovery
MAR 10, 2019In a study published in the Journal of Biological Chemistry, a diet containing green tea and carrots reversed Alzheimer's-like symptoms in mice that ar...Written By: Nouran AminMAR 10, 2019Microbiology
MAR 10, 2019In recent years, fungal disease has decimated amphibian populations; some species went extinct. But others withstood the epidemic....Written By: Carmen LeitchMAR 09, 2019Videos
MAR 09, 2019In 1928, Alexander Fleming found a contaminated Petri dish, and from there, humanity's use of antibiotics started....Written By: Carmen LeitchMAR 06, 2019Immunology
MAR 06, 2019Scientists discover a formulation of a vaccine for TB that protects better than the current vaccine....Written By: Nicholas BreehlMAR 06, 2019Immunology
MAR 06, 2019Researchers have discovered how a tiny molecule is known as miR-132 which helps to fight infection...Written By: Nicholas BreehlMAR 03, 2019Drug Discovery
MAR 03, 2019Recently, researchers have identified a drug that could help reverse the damaging effects of heavy alcohol consumption on the regeneration of neurons (brai...Written By: Nouran AminMAR 01, 2019Drug Discovery
MAR 01, 2019Researchers report in a study published in the journal Stem Cell Reports, that nicotine exerted adverse effects on human embryonic development at the cellu...Written By: Nouran AminFEB 27, 2019Immunology
FEB 27, 2019Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide....Written By: Nicholas BreehlFEB 25, 2019Drug Discovery
FEB 25, 2019According to a new research study published eNeuro, investigations of methylphenidate (Ritalin) on neuronal activity in monkeys held no effects on the pref...Written By: Nouran AminFEB 25, 2019Drug Discovery
FEB 25, 2019Researchers have developed a 3D hydrogel based on hyaluronic acid, a biocompatible substance. The gel could quickly and effectively screen hundreds of pote...Written By: Nouran AminFEB 25, 2019Drug Discovery
FEB 25, 2019Parkinson’s disease and Amyotrophic Lateral Sclerosis is the latest push for Medicines 4 Neurodegenerative Diseases (M4ND Pharma) by academic scienti...Written By: Nouran AminFEB 25, 2019Drug Discovery
FEB 25, 2019Photoelectrochemical (PEC) cells utilize photocathodes and photoanodes to "split" water into hydrogen and oxygen. PEC cells have been primarily s...Written By: Nouran AminFEB 24, 2019Drug Discovery
FEB 24, 2019Individuals diagnosed with Duchenne muscular dystrophy (DMD) face few treatment options. DMD is a progressive muscle weakness and degeneration with loss of...Written By: Nouran AminFEB 21, 2019Genetics & Genomics
FEB 21, 2019While cancer rates are dropping in general, colorectal cancer is becoming more common in people under the age of 55....Written By: Carmen Leitch
MAR 20, 2019
Drug Discovery
MAR 20, 2019
The U.S. Food and Drug Administration recently approved the first ever drug specifically for the treatment of postpartum depression a common and often deva...
Written By:
Nouran Amin
MAR 19, 2019
Health & Medicine
MAR 19, 2019
A pilot study suggests it might. Researchers at the University of Alabama, Birmingham, found that a low-carbohydrate diet was able to reduce pain intensity...
Written By:
Aleishia Harris-Arnold
MAR 18, 2019
Cell & Molecular Biology
MAR 18, 2019
Cystic fibrosis affects around 700,000 people worldwide. New research has found a potential treatment for patients that don't respond to current therapies....
Written By:
Carmen Leitch
MAR 15, 2019
Drug Discovery
MAR 15, 2019
A virus-like particle vaccine was developed to stop chronic pain caused by osteoarthritis inhibiting a nerve growth factor (NGF). The vaccine was administe...
Written By:
Nouran Amin
MAR 14, 2019
Cannabis Sciences
MAR 14, 2019
Cirrhosis accounts for 31,000 deaths per year. Approximately 3.5 to 4.6 million people in the U.S. are chronically infected with the hepatitis C...
Written By:
Amy Loriaux
MAR 13, 2019
Drug Discovery
MAR 13, 2019
The number of individuals diagnosed with liver cancer is on the rise and current therapies are largely ineffective. However, new preclinical data from the ...
Written By:
Nouran Amin
MAR 13, 2019
Immunology
MAR 13, 2019
Researchers have utilized cryo-electron microscopy to identify new cell membrane proteins...
Written By:
Nicholas Breehl
MAR 13, 2019
Cell & Molecular Biology
MAR 13, 2019
An ever-increasing number of bacteria are able to evade the effects of antibiotics, which is considered a serious threat to public health....
Written By:
Carmen Leitch
MAR 11, 2019
Drug Discovery
MAR 11, 2019
In a recent research study, precision cancer drugs called PARP inhibitors are previously known to boost the immune system were found to spark a powerful im...
Written By:
Nouran Amin
MAR 11, 2019
Drug Discovery
MAR 11, 2019
Many individuals going through depression gain little benefit from treatments whether drugs or talk therapy. Depression represents one of the greatest unme...
Written By:
Nouran Amin
MAR 10, 2019
Drug Discovery
MAR 10, 2019
In a study published in the Journal of Biological Chemistry, a diet containing green tea and carrots reversed Alzheimer's-like symptoms in mice that ar...
Written By:
Nouran Amin
MAR 10, 2019
Microbiology
MAR 10, 2019
In recent years, fungal disease has decimated amphibian populations; some species went extinct. But others withstood the epidemic....
Written By:
Carmen Leitch
MAR 09, 2019
Videos
MAR 09, 2019
In 1928, Alexander Fleming found a contaminated Petri dish, and from there, humanity's use of antibiotics started....
Written By:
Carmen Leitch
MAR 06, 2019
Immunology
MAR 06, 2019
Scientists discover a formulation of a vaccine for TB that protects better than the current vaccine....
Written By:
Nicholas Breehl
MAR 06, 2019
Immunology
MAR 06, 2019
Researchers have discovered how a tiny molecule is known as miR-132 which helps to fight infection...
Written By:
Nicholas Breehl
MAR 03, 2019
Drug Discovery
MAR 03, 2019
Recently, researchers have identified a drug that could help reverse the damaging effects of heavy alcohol consumption on the regeneration of neurons (brai...
Written By:
Nouran Amin
MAR 01, 2019
Drug Discovery
MAR 01, 2019
Researchers report in a study published in the journal Stem Cell Reports, that nicotine exerted adverse effects on human embryonic development at the cellu...
Written By:
Nouran Amin
FEB 27, 2019
Immunology
FEB 27, 2019
Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide....
Written By:
Nicholas Breehl
FEB 25, 2019
Drug Discovery
FEB 25, 2019
According to a new research study published eNeuro, investigations of methylphenidate (Ritalin) on neuronal activity in monkeys held no effects on the pref...
Written By:
Nouran Amin
FEB 25, 2019
Drug Discovery
FEB 25, 2019
Researchers have developed a 3D hydrogel based on hyaluronic acid, a biocompatible substance. The gel could quickly and effectively screen hundreds of pote...
Written By:
Nouran Amin
FEB 25, 2019
Drug Discovery
FEB 25, 2019
Parkinson’s disease and Amyotrophic Lateral Sclerosis is the latest push for Medicines 4 Neurodegenerative Diseases (M4ND Pharma) by academic scienti...
Written By:
Nouran Amin
FEB 25, 2019
Drug Discovery
FEB 25, 2019
Photoelectrochemical (PEC) cells utilize photocathodes and photoanodes to "split" water into hydrogen and oxygen. PEC cells have been primarily s...
Written By:
Nouran Amin
FEB 24, 2019
Drug Discovery
FEB 24, 2019
Individuals diagnosed with Duchenne muscular dystrophy (DMD) face few treatment options. DMD is a progressive muscle weakness and degeneration with loss of...
Written By:
Nouran Amin
FEB 21, 2019
Genetics & Genomics
FEB 21, 2019
While cancer rates are dropping in general, colorectal cancer is becoming more common in people under the age of 55....
Written By:
Carmen Leitch
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