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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • JUL 23, 2022
      Drug Discovery & Development
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      Antibiotics Affect Gut Microbiome of Male and Female Rats Differently
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      JUL 23, 2022
      Health & Medicine
      Anti-inflammatory Compound Shows Promise in Treating Severe COVID-19
      Anti-inflammatory Compound Shows Promise in Treating Severe COVID-19
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      JUL 22, 2022
      Health & Medicine
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      Researchers Say Nasal Boosters Will be Important to Stopping COVID
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      JUL 21, 2022
      Immunology
      For the First Time, Microscopy Catches Antibodies Attacking a Receptor
      For the First Time, Microscopy Catches Antibodies Attacking a Receptor
      Using cryo-electron microscopy, researchers captured images of a molecule called an autoantibody as it attached to a rec ...
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      JUL 21, 2022
      Cell & Molecular Biology
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      'Junk' DNA May Stall Replication, Increasing Cancer Risk
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      JUL 20, 2022
      Neuroscience
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      Stress Transmitter Wakes Up the Sleeping Brain Over 100 Times Per Night
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      JUL 20, 2022
      Microbiology
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      JUL 19, 2022
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      JUL 16, 2022
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      JUL 16, 2022
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      JUL 15, 2022
      Immunology
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      JUL 15, 2022
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      JUL 14, 2022
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      JUL 14, 2022
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      JUL 14, 2022
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      JUL 14, 2022
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      JUL 13, 2022
      Clinical & Molecular DX
      Nipah Virus: Moderna Invests in a Vaccine for the Virus that Fauci Calls a 'Pandemic Threat'
      Nipah Virus: Moderna Invests in a Vaccine for the Virus that Fauci Calls a 'Pandemic Threat'
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      JUL 12, 2022
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      JUL 11, 2022
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      JUL 09, 2022
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      Universal Vaccine for Influenza B Shows Promise
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      JUL 08, 2022
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      $2 Million in NIH Awards go to Study Adolescent Cannabis Use
      $2 Million in NIH Awards go to Study Adolescent Cannabis Use
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      JUL 08, 2022
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      JUL 07, 2022
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    JUL 23, 2022
    Drug Discovery & Development
    Antibiotics Affect Gut Microbiome of Male and Female Rats Differently
    Antibiotics Affect Gut Microbiome of Male and Female Rats Differently
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    Written By: Annie Lennon
    2
    JUL 23, 2022
    Health & Medicine
    Anti-inflammatory Compound Shows Promise in Treating Severe COVID-19
    Anti-inflammatory Compound Shows Promise in Treating Severe COVID-19
    An anti-inflammatory compound has shown promise in treating systemic inflammation and brain injury in patients with seve ...
    Written By: Annie Lennon
    2
    JUL 22, 2022
    Health & Medicine
    Researchers Say Nasal Boosters Will be Important to Stopping COVID
    Researchers Say Nasal Boosters Will be Important to Stopping COVID
    The SARS-CoV-2 virus has continued to evolve since the start of the pandemic, and we've moved down the list of variants ...
    Written By: Carmen Leitch
    1
    JUL 21, 2022
    Immunology
    For the First Time, Microscopy Catches Antibodies Attacking a Receptor
    For the First Time, Microscopy Catches Antibodies Attacking a Receptor
    Using cryo-electron microscopy, researchers captured images of a molecule called an autoantibody as it attached to a rec ...
    Written By: Carmen Leitch
    1
    JUL 21, 2022
    Cell & Molecular Biology
    'Junk' DNA May Stall Replication, Increasing Cancer Risk
    'Junk' DNA May Stall Replication, Increasing Cancer Risk
    Huge sections of the human genome are made up of highly repetitive sequences, areas where bases like ATATAT repeat in lo ...
    Written By: Carmen Leitch
    1
     
     
  • JUL 20, 2022
    Neuroscience
    Stress Transmitter Wakes Up the Sleeping Brain Over 100 Times Per Night
    Stress Transmitter Wakes Up the Sleeping Brain Over 100 Times Per Night
    A study published in Nature Neuroscience reported that the stress hormone and transmitter noradrenaline wakes up the hum ...
    Written By: Kerry Charron
    1
    JUL 20, 2022
    Microbiology
    Halting the Assembly of Dangerous Paramyxoviruses Like Nipah
    Halting the Assembly of Dangerous Paramyxoviruses Like Nipah
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    Written By: Carmen Leitch
    1
    JUL 20, 2022
    Neuroscience
    What Does the Sleeping Brain Do When It Hears Music?
    What Does the Sleeping Brain Do When It Hears Music?
    A study published in Nature Neuroscience highlights brain activity that happens when a sleeping person hears music. A te ...
    Written By: Kerry Charron
    1
    JUL 19, 2022
    Drug Discovery & Development
    Experimental Cancer Drug Regrows Nerves in Spinal Cord Injury
    Experimental Cancer Drug Regrows Nerves in Spinal Cord Injury
    An experimental cancer drug can regenerate damaged nerves following spinal trauma in mice and rats. The corresponding re ...
    Written By: Annie Lennon
    2
    JUL 16, 2022
    Drug Discovery & Development
    Oxytocin Nasal Sprays Don't Improve Emotion Recognition in Healthy Individuals
    Oxytocin Nasal Sprays Don't Improve Emotion Recognition in Healthy Individuals
    Oxytocin nasal sprays do not improve the recognition of emotions such as anger and sadness in healthy men without autism ...
    Written By: Annie Lennon
    1
     
     
  • JUL 16, 2022
    Drug Discovery & Development
    Whole Blood Exchange May Reduce Amyloid Plaques in Alzheimer's
    Whole Blood Exchange May Reduce Amyloid Plaques in Alzheimer's
    Whole blood exchange reduces the formation of amyloid beta plaques in mouse models of Alzheimer's disease. The corre ...
    Written By: Annie Lennon
    4
    JUL 15, 2022
    Immunology
    Pox Virus Proteins Can Launch Early Attack on Immune Defense
    Pox Virus Proteins Can Launch Early Attack on Immune Defense
    After a virus gets inside of a cell, it typically takes over the cell to produce more viral particles. But pox viruses g ...
    Written By: Carmen Leitch
    2
    JUL 15, 2022
    Cannabis Sciences
    Cannabis Legalization's Impact on Foster Care Placements
    Cannabis Legalization's Impact on Foster Care Placements
    A study published in the journal Economic Inquiry analyzed the potential impacts of federal cannabis legalization on fos ...
    Written By: Kerry Charron
    2
    JUL 14, 2022
    Plants & Animals
    Using Worms to Study Precision Medicine
    Using Worms to Study Precision Medicine
    Personalized medicine refers to making decisions about treatment that are optimized to a specific individual, often as a ...
    Written By: Ryan Vingum
    3
    JUL 14, 2022
    Clinical & Molecular DX
    Emerging Research Could Soon Solve the Parkinson's Disease Diagnosis Challenge
    Emerging Research Could Soon Solve the Parkinson's Disease Diagnosis Challenge
    Parkinson’s disease is a brain disorder with symptoms that begin gradually and worsen over time. Symptoms of Parki ...
    Written By: Zoe Michaud
    2
     
     
  • JUL 14, 2022
    Clinical & Molecular DX
    A magnetic bead for every need: Expanding applications with conjugated magnetic beads
    A magnetic bead for every need: Expanding applications with conjugated magnetic beads
    Magnetic beads (or superparamagnetic particles) can be used for the isolation and purification of cells, nucleic acids, ...
    Sponsored By: Cytiva
    6
    JUL 14, 2022
    Cancer
    Acupuncture Can Help Control Cancer-Related Pain
    Acupuncture Can Help Control Cancer-Related Pain
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    Written By: Katie Kokolus
    4
    JUL 13, 2022
    Clinical & Molecular DX
    Nipah Virus: Moderna Invests in a Vaccine for the Virus that Fauci Calls a 'Pandemic Threat'
    Nipah Virus: Moderna Invests in a Vaccine for the Virus that Fauci Calls a 'Pandemic Threat'
    In Malaysia in the fall of 1998, a mystery ailment swept through the local pig-farming community, eventually leading to ...
    Written By: Zoe Michaud
    1
    JUL 12, 2022
    Drug Discovery & Development
    Nitric Oxide Reduces Hospital Stay of Pregnant Women with COVID-19
    Nitric Oxide Reduces Hospital Stay of Pregnant Women with COVID-19
    High-dose nitric oxide can reduce the length of hospital and ICU stay, as well as the need for supplemental oxygen, amon ...
    Written By: Annie Lennon
    3
    JUL 11, 2022
    Cancer
    Boosting CAR T Cell Therapy with TIGIT Blockade
    Boosting CAR T Cell Therapy with TIGIT Blockade
    Chimeric antigen receptor (CAR) T Cell therapy has emerged as a promising immunotherapeutic approach to treat blood canc ...
    Written By: Katie Kokolus
    4
     
     
  • JUL 09, 2022
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    Universal Vaccine for Influenza B Shows Promise
    Universal Vaccine for Influenza B Shows Promise
    A new universal flu vaccine has been shown to protect against influenza B viruses in cell and mouse models. The correspo ...
    Written By: Annie Lennon
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    JUL 08, 2022
    Cannabis Sciences
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    $2 Million in NIH Awards go to Study Adolescent Cannabis Use
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    Written By: Kerry Charron
    2
    JUL 08, 2022
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    The Latest Research on Cannabis Social Equity Programs
    The Latest Research on Cannabis Social Equity Programs
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    JUL 07, 2022
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    Mini-Kidneys Reveal New Insights, Treatments for Multiple Disorders
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