Follow
Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
-
SEP 18, 2025Immunology
Cancer is a complex disease that evades the immune system through various mechanisms. The rapid proliferation of cells a ...Written By: Brian G. MorrealeSEP 16, 2025eBooksImproving the solubility and bioavailability of poorly soluble APIs remains one of the toughest challenges in pharmaceut ...Sponsored By: Thermo Fisher ScientificSEP 15, 2025eBooksFormulation scientists face mounting pressure to bring complex molecules to market with higher efficacy, stability, and ...Sponsored By: Thermo Fisher ScientificSEP 15, 2025Cancer
Plasticity in cancer cells describes their inherent ability to undergo alterations and turn certain features on and off ...Written By: Katie KokolusSEP 02, 2025eBooksResearchers are under pressure to scale complex cell culture models-like iPSCs and 3D organoids-for high-throughput drug ...Sponsored By: Molecular DevicesAUG 31, 2025Cell & Molecular Biology
Chronic kidney disease (CKD) has been called an “under-recognized public health crisis,” and is estimated to ...Written By: Carmen LeitchAUG 25, 2025Cancer
Immune checkpoint inhibitors (ICIs) have revolutionized the field of cancer immuno-oncology. ICIs act on cancer ce ...Written By: Katie KokolusAUG 22, 2025Microbiology
As bacterial pathogens evolve, the common antibiotics used to treat these bacterial infections have become less effectiv ...Written By: Carmen LeitchAUG 18, 2025eBooksAlzheimer’s disease (AD) is the most common form of dementia, thought to affect approximately 50 million people wo ...AUG 18, 2025eBooksManual and automated plasmid purification methods each have their distinct approaches. Manual purification is hands-on a ...Sponsored By: Thermo Fisher ScientificAUG 12, 2025eBooksDrug development is evolving—fast. What once took years must now happen in months, and the demand for flexibility, ...Sponsored By: Thermo Fisher ScientificAUG 12, 2025Drug Discovery & Development
Fig 1. Cytiva Superdex 75 Size Exclusion Chromatography (SEC) column Separation of molecules is performed using S ...AUG 08, 2025Drug Discovery & DevelopmentLipid nanoparticles (LNPs) and liposomes (Figure 1) have revolutionized the medical field by serving as carriers for a w ...Sponsored By: Beckman Coulter Life SciencesAUG 05, 2025eBooksAs 3D cell culture becomes a cornerstone of modern R&D, achieving consistency and reproducibility in liquid handling ...AUG 05, 2025Drug Discovery & Development
Understanding and characterizing complex compounds is essential for drug discovery and development. Chromatography is a ...AUG 05, 2025Cell & Molecular Biology
An interview with Lindy O’Clair, Head of Incucyte® Product Management at Sartorius 3D cell models like spheroi ...JUL 28, 2025Drug Discovery & Development
One lab technique that has been around since what feels like the dawn of time is Western blotting, and it doesn&r ...JUL 23, 2025Drug Discovery & Development
Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceutical ...JUL 21, 2025Microbiology
Many known viruses pose a continuing threat to public health, and we are constantly dealing with the possibility that ne ...Written By: Carmen LeitchJUL 15, 2025Health & Medicine
For years, pharmaceutical scientists have sought to enhance bioavailability by transforming drugs from their crystalline ...Sponsored By: Thermo Fisher ScientificJUL 10, 2025Microbiology
Remnants of everything that humans ingest ends up in waste water, including medications that people may be taking, like ...Written By: Carmen LeitchJUL 07, 2025Cancer
Nasopharyngeal carcinoma (NPC), a malignancy that develops in the upper section of the throat behind the nose, occurs in ...Written By: Katie KokolusJUL 04, 2025Genetics & Genomics
This study has shown that HSV-1 is an "opportunistic interior designer" of human cells.Written By: Carmen LeitchJUL 02, 2025Cell & Molecular Biology
Multiple sclerosis (MS) is a chronic inflammatory disorder that is thought to impact about 2.3 million people around the ...Written By: Carmen Leitch
![Alzheimer's Disease Pathway [Infographic]](https://d3bkbkx82g74b8.cloudfront.net/eyJidWNrZXQiOiJsYWJyb290cy1pbWFnZXMiLCJrZXkiOiJjb250ZW50X2FydGljbGVfcHJvZmlsZV9pbWFnZV8xMmVjNTUzMjVkMTUzODU2OGJlOGYwYzRiYzJmODc5MGE1ZGM1MDljXzI0NjEuanBnIiwiZWRpdHMiOnsidG9Gb3JtYXQiOiJqcGciLCJyZXNpemUiOnsid2lkdGgiOjcwMCwiaGVpZ2h0IjozNTAsImZpdCI6ImNvdmVyIiwicG9zaXRpb24iOiJjZW50ZXIiLCJiYWNrZ3JvdW5kIjoiI2ZmZiJ9LCJmbGF0dGVuIjp7ImJhY2tncm91bmQiOiIjZmZmIn19fQ==)
SEP 18, 2025
Immunology
Cancer is a complex disease that evades the immune system through various mechanisms. The rapid proliferation of cells a
...
Written By:
Brian G. Morreale
SEP 16, 2025
eBooks
Improving the solubility and bioavailability of poorly soluble APIs remains one of the toughest challenges in pharmaceut
...
Sponsored By:
Thermo Fisher Scientific
SEP 15, 2025
eBooks
Formulation scientists face mounting pressure to bring complex molecules to market with higher efficacy, stability, and
...
Sponsored By:
Thermo Fisher Scientific
SEP 15, 2025
Cancer
Plasticity in cancer cells describes their inherent ability to undergo alterations and turn certain features on and off
...
Written By:
Katie Kokolus
SEP 02, 2025
eBooks
Researchers are under pressure to scale complex cell culture models-like iPSCs and 3D organoids-for high-throughput drug
...
Sponsored By:
Molecular Devices
AUG 31, 2025
Cell & Molecular Biology
Chronic kidney disease (CKD) has been called an “under-recognized public health crisis,” and is estimated to
...
Written By:
Carmen Leitch
AUG 25, 2025
Cancer
Immune checkpoint inhibitors (ICIs) have revolutionized the field of cancer immuno-oncology. ICIs act on cancer ce
...
Written By:
Katie Kokolus
AUG 22, 2025
Microbiology
As bacterial pathogens evolve, the common antibiotics used to treat these bacterial infections have become less effectiv
...
Written By:
Carmen Leitch
AUG 18, 2025
eBooks
Alzheimer’s disease (AD) is the most common form of dementia, thought to affect approximately 50 million people wo
...
AUG 18, 2025
eBooks
Manual and automated plasmid purification methods each have their distinct approaches. Manual purification is hands-on a
...
Sponsored By:
Thermo Fisher Scientific
AUG 12, 2025
eBooks
Drug development is evolving—fast. What once took years must now happen in months, and the demand for flexibility,
...
Sponsored By:
Thermo Fisher Scientific
AUG 12, 2025
Drug Discovery & Development
Fig 1. Cytiva Superdex 75 Size Exclusion Chromatography (SEC) column Separation of molecules is performed using S
...
AUG 08, 2025
Drug Discovery & Development
Lipid nanoparticles (LNPs) and liposomes (Figure 1) have revolutionized the medical field by serving as carriers for a w
...
Sponsored By:
Beckman Coulter Life Sciences
AUG 05, 2025
eBooks
As 3D cell culture becomes a cornerstone of modern R&D, achieving consistency and reproducibility in liquid handling
...
AUG 05, 2025
Drug Discovery & Development
Understanding and characterizing complex compounds is essential for drug discovery and development. Chromatography is a
...
AUG 05, 2025
Cell & Molecular Biology
An interview with Lindy O’Clair, Head of Incucyte® Product Management at Sartorius 3D cell models like spheroi
...
JUL 28, 2025
Drug Discovery & Development
One lab technique that has been around since what feels like the dawn of time is Western blotting, and it doesn&r
...
JUL 23, 2025
Drug Discovery & Development
Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceutical
...
JUL 21, 2025
Microbiology
Many known viruses pose a continuing threat to public health, and we are constantly dealing with the possibility that ne
...
Written By:
Carmen Leitch
JUL 15, 2025
Health & Medicine
For years, pharmaceutical scientists have sought to enhance bioavailability by transforming drugs from their crystalline
...
Sponsored By:
Thermo Fisher Scientific
JUL 10, 2025
Microbiology
Remnants of everything that humans ingest ends up in waste water, including medications that people may be taking, like
...
Written By:
Carmen Leitch
JUL 07, 2025
Cancer
Nasopharyngeal carcinoma (NPC), a malignancy that develops in the upper section of the throat behind the nose, occurs in
...
Written By:
Katie Kokolus
JUL 04, 2025
Genetics & Genomics
This study has shown that HSV-1 is an "opportunistic interior designer" of human cells.
Written By:
Carmen Leitch
JUL 02, 2025
Cell & Molecular Biology
Multiple sclerosis (MS) is a chronic inflammatory disorder that is thought to impact about 2.3 million people around the
...
Written By:
Carmen Leitch