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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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APR 13, 2020Cardiology
Cardiotoxicity, heart electrophysiology dysfunction or muscle damage, is one of the most common reasons why drugs ...Written By: Annie LennonAPR 13, 2020Drug Discovery & Development
Although treatments and vaccines against COVID-19 may still be months away, antibody tests are becoming more widespread. ...Written By: Annie LennonAPR 12, 2020Drug Discovery & Development
Can spider venom offer pain relief? Apparently, yes! According to researchers at University of Queensland, compounds iso ...Written By: Nouran AminAPR 11, 2020Drug Discovery & Development
At St. Jude Children’s Research Hospital, researchers discovered a fast-acting anti-malarial compound with promisi ...Written By: Nouran AminAPR 11, 2020Drug Discovery & Development
An early analysis of remdesivir, a drug developed by pharmaceutical firm Gilead, has shown that it may have improved sev ...Written By: Annie LennonAPR 11, 2020Cardiology
Using cell therapy, researchers from Lund University in Sweden have successfully restored mobility and a sense of touch ...Written By: Annie LennonAPR 10, 2020Drug Discovery & Development
According to a study published in the journal Science Translational Medicine, a therapeutic previously used for cancer t ...Written By: Nouran AminAPR 10, 2020Drug Discovery & Development
Heart attacks significantly damage cardiac tissue. Recovery time frames from a heart attack thus depend on the extent to ...Written By: Annie LennonAPR 10, 2020Cardiology
Black tea is among one of the most commonly consumed beverages around the world. Beyond just being a refreshing and ener ...Written By: Annie LennonAPR 09, 2020Drug Discovery & Development
Although US President Donald Trump is a strong supporter of antimalarial drug Hydroxychloroquine as a treatment for COVI ...Written By: Annie LennonAPR 09, 2020Drug Discovery & Development
Over-the-counter antihistamine treatments are known to be effective for relieving allergic symptoms. However, they are a ...Written By: Annie LennonAPR 08, 2020Cancer
New research published in Cancer Discovery suggests that manipulating the pH of pancreatic cancer cells can deter cell g ...Written By: Kathryn DeMuth SullivanAPR 08, 2020Neuroscience
It's easy to gauge a dog or cat's emotion by reading their facial expression, but the same has been historically ...Written By: Amanda MikyskaAPR 07, 2020Microbiology
Yesterday, Inovio Pharmaceuticals, Inc. announced that it will begin human trials on a potential vaccine for COVID-19.Written By: Carmen LeitchAPR 06, 2020Cancer
Hepatocellular carcinoma, or HCC, is a type of liver cancer, and the third most prevalent cancer-caused death in ...Written By: Jasper CantrellAPR 05, 2020Drug Discovery & Development
As death tolls continue to rise from COVID-19, the scramble for new treatments to counter the virus surges on. Now, rese ...Written By: Annie LennonAPR 04, 2020Cancer
In cancer, tyrosine kinase mutations are quite common. MET is one such example that normally binds its native lig ...Written By: Jasper CantrellAPR 03, 2020Drug Discovery & Development
A collaborative team of researchers joined forces to study the anti-parasitic drug, Ivermectin, and it’s role in s ...Written By: Nouran AminAPR 02, 2020Chemistry & Physics
With vaccines at least one year away and no proven treatment for infection, the world has witnessed the loss of 20 ...Written By: Daniel DuanAPR 01, 2020Cancer
Research published recently in the Journal of Experimental Medicine suggests that targeting macrophages in a new kind of ...Written By: Kathryn DeMuth SullivanMAR 31, 2020Microbiology
As SARS-CoV-2 upends normalcy in the world, researchers are trying to find a treatment for the illness it causes.Written By: Carmen LeitchMAR 31, 2020Cancer
Research published in the journal Molecular Cancer Research from collaborators at the University of Colorado C ...Written By: Kathryn DeMuth SullivanMAR 30, 2020Genetics & Genomics
The gene enables bacteria to resist the effects of an aminoglycoside antibiotic called plazomycin.Written By: Carmen LeitchMAR 29, 2020Cancer
Have you ever heard of ependymoma? This rare form of brain cancer most commonly occurs in young children when tumors for ...Written By: Kathryn DeMuth Sullivan
APR 13, 2020
Cardiology
Cardiotoxicity, heart electrophysiology dysfunction or muscle damage, is one of the most common reasons why drugs
...
Written By:
Annie Lennon
APR 13, 2020
Drug Discovery & Development
Although treatments and vaccines against COVID-19 may still be months away, antibody tests are becoming more widespread.
...
Written By:
Annie Lennon
APR 12, 2020
Drug Discovery & Development
Can spider venom offer pain relief? Apparently, yes! According to researchers at University of Queensland, compounds iso
...
Written By:
Nouran Amin
APR 11, 2020
Drug Discovery & Development
At St. Jude Children’s Research Hospital, researchers discovered a fast-acting anti-malarial compound with promisi
...
Written By:
Nouran Amin
APR 11, 2020
Drug Discovery & Development
An early analysis of remdesivir, a drug developed by pharmaceutical firm Gilead, has shown that it may have improved sev
...
Written By:
Annie Lennon
APR 11, 2020
Cardiology
Using cell therapy, researchers from Lund University in Sweden have successfully restored mobility and a sense of touch
...
Written By:
Annie Lennon
APR 10, 2020
Drug Discovery & Development
According to a study published in the journal Science Translational Medicine, a therapeutic previously used for cancer t
...
Written By:
Nouran Amin
APR 10, 2020
Drug Discovery & Development
Heart attacks significantly damage cardiac tissue. Recovery time frames from a heart attack thus depend on the extent to
...
Written By:
Annie Lennon
APR 10, 2020
Cardiology
Black tea is among one of the most commonly consumed beverages around the world. Beyond just being a refreshing and ener
...
Written By:
Annie Lennon
APR 09, 2020
Drug Discovery & Development
Although US President Donald Trump is a strong supporter of antimalarial drug Hydroxychloroquine as a treatment for COVI
...
Written By:
Annie Lennon
APR 09, 2020
Drug Discovery & Development
Over-the-counter antihistamine treatments are known to be effective for relieving allergic symptoms. However, they are a
...
Written By:
Annie Lennon
APR 08, 2020
Cancer
New research published in Cancer Discovery suggests that manipulating the pH of pancreatic cancer cells can deter cell g
...
Written By:
Kathryn DeMuth Sullivan
APR 08, 2020
Neuroscience
It's easy to gauge a dog or cat's emotion by reading their facial expression, but the same has been historically
...
Written By:
Amanda Mikyska
APR 07, 2020
Microbiology
Yesterday, Inovio Pharmaceuticals, Inc. announced that it will begin human trials on a potential vaccine for COVID-19.
Written By:
Carmen Leitch
APR 06, 2020
Cancer
Hepatocellular carcinoma, or HCC, is a type of liver cancer, and the third most prevalent cancer-caused death in
...
Written By:
Jasper Cantrell
APR 05, 2020
Drug Discovery & Development
As death tolls continue to rise from COVID-19, the scramble for new treatments to counter the virus surges on. Now, rese
...
Written By:
Annie Lennon
APR 04, 2020
Cancer
In cancer, tyrosine kinase mutations are quite common. MET is one such example that normally binds its native lig
...
Written By:
Jasper Cantrell
APR 03, 2020
Drug Discovery & Development
A collaborative team of researchers joined forces to study the anti-parasitic drug, Ivermectin, and it’s role in s
...
Written By:
Nouran Amin
APR 02, 2020
Chemistry & Physics
With vaccines at least one year away and no proven treatment for infection, the world has witnessed the loss of 20
...
Written By:
Daniel Duan
APR 01, 2020
Cancer
Research published recently in the Journal of Experimental Medicine suggests that targeting macrophages in a new kind of
...
Written By:
Kathryn DeMuth Sullivan
MAR 31, 2020
Microbiology
As SARS-CoV-2 upends normalcy in the world, researchers are trying to find a treatment for the illness it causes.
Written By:
Carmen Leitch
MAR 31, 2020
Cancer
Research published in the journal Molecular Cancer Research from collaborators at the University of Colorado C
...
Written By:
Kathryn DeMuth Sullivan
MAR 30, 2020
Genetics & Genomics
The gene enables bacteria to resist the effects of an aminoglycoside antibiotic called plazomycin.
Written By:
Carmen Leitch
MAR 29, 2020
Cancer
Have you ever heard of ependymoma? This rare form of brain cancer most commonly occurs in young children when tumors for
...
Written By:
Kathryn DeMuth Sullivan