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    Fundamental research

    Fundamental research, in comparison to applied research, is an area of scientific research that focuses on progressing rudimentary scientific theories with the goal of further understanding scientific basics and making educated predictions on observed phenomena.

    Webinars

    • AUG 06, 2020 | 12:00 AM
      Mechanistic basis for the evolution of eukaryotic specialized metabolism
      Mechanistic basis for the evolution of eukaryotic specialized...
      Primary metabolism supports essential chemical processes of living organisms, and is highly conserved among all life forms. In contrast, specialized metabolism contributes to the fitness of...
      Speaker: Jing-Ke Weng, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      Tracking Genome Dynamics in Time and Space
      Tracking Genome Dynamics in Time and Space
      Extrachromosomal circular DNA (eccDNA) comprises products of genomic recombination that cause somatic changes in gene length and sequence. These circular molecules are derived from canonical...
      Speaker: Massa Shoura, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 29, 2020 | 10:00 AM
      Metabolic control of T cell tolerance and antitumor immunity
      Metabolic control of T cell tolerance and antitumor immunity
      Coordination of immune cell metabolic programs with cell fate and state is a fundamental determinant of immune responses. Emerging evidence highlights that the interplay between immune signa...
      Speaker: Hongbo Chi, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 8:00 AM
      High-throughput DNA damage analyses identify synergistic drug combinations to treat malignant brain tumours
      High-throughput DNA damage analyses identify synergistic drug...
      Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
      Speaker: Sachin Katyal, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 7:00 AM
      What intratumoral Tregs eat makes them strong, but vulnerable: a new metabolic intervention for cancer immunotherapy
      What intratumoral Tregs eat makes them strong, but vulnerable:...
      Metabolic reprogramming is critical for governing proper T cell immune responses, including activation, production of effector molecule, migration and differentiation. The metabolic stress T...
      Speaker: Ping-Chih Ho, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 08, 2020 | 11:00 PM
      Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
      Mass Spectrometry Past and Present - Emerging Technologies and...
      DATE: July 9, 2020 TIME: 2pm SGT, 3pm JST, 4pm AEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not until around 30 to 40...
      Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
      Sponsored By: Waters Corporation
      17
      JUN 25, 2020 | 8:00 AM
      Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
      Mass Spectrometry Past and Present - Emerging Technologies and...
      DATE: June 25, 2020 TIME: 8:00am PDT, 11:00am EDT, 4:00pm BST, 5:00pm CEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not...
      Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
      Sponsored By: Waters Corporation
      34
      JUN 24, 2020 | 10:00 AM
      The Fundamentals of Freeze Drying: Advice from the experts on how to get started
      The Fundamentals of Freeze Drying: Advice from the experts on...
      DATE: June 24, 2020 TIME: 10:00am PT Does your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize your lyo...
      Speaker: Megan Zimerman, B.A. in Biology , Jenny Sprung
      Sponsored By: Labconco
      18 1
      JUN 18, 2020 | 10:30 AM
      Investigating Sensitivity Improvements on the Ultivo TQ using 3D-printed Atmospheric Pressure ion Focusing Devices
      Investigating Sensitivity Improvements on the Ultivo TQ using...
      While the introduction of atmospheric pressure ion sources, such as electrospray ionization, revolutionized the field of mass spectrometry it also introduced new instrumental compilations no...
      Speaker: Patrick Batoon, PhD , Brett Marsh, PhD
      Presented at: Agilent's Virtual Mass Spectacular!
      2
      JUN 17, 2020 | 3:00 PM
      COVID-19: Enrichment and analysis of rare antigen- and virus-specific T cells
      COVID-19: Enrichment and analysis of rare antigen- and virus-specific...
      Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious diseases, immuno-oncology, as well...
      Speaker: Dr. Marcello Stein
      Presented at: Coronavirus Series
      Sponsored By: Miltenyi Biotec
      1
      JUN 16, 2020 | 7:00 AM
      Savor the Flavor: Keeping Meat Products Safe with a Veterinary Drug Screening Comprehensive Workflow Solution
      Savor the Flavor: Keeping Meat Products Safe with a Veterinary...
      Veterinary drugs are commonly used chemicals to improve the growth and health outcomes of farm animals raised for human consumption. However, improper use of vet-drugs in animal farming can...
      Speaker: Patrick Batoon, PhD , Siji Joseph
      Presented at: Agilent's Virtual Mass Spectacular!
      4
      JUN 04, 2020 | 2:00 PM
      Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration and Invasion
      Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration...
      In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
      Speaker: KEYNOTE: Claire Brown, PhD
      Presented at: Cell & Developmental Biology Virtual Meeting
      3
      JUN 03, 2020 | 12:00 PM
      Single cell multiomic analysis of T-cell exhaustion
      Single cell multiomic analysis of T-cell exhaustion
      A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
      Speaker: Pratip K. Chattopadhyay
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: BD
      2
      MAY 27, 2020 | 9:00 AM
      Enrichment & analysis of rare antigen & virus-specific T cells
      Enrichment & analysis of rare antigen & virus-specific T cells
      DATE: May 27, 2020 TIME: 9:00am PT Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious...
      Speaker: Marcello Stein, PhD.
      Sponsored By: Miltenyi Biotec
      20
      MAY 20, 2020 | 12:00 AM
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
      Speaker: Joseph de Rutte
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCR™
      Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCR™
      The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
      Speaker: Rémi Dangla
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 14, 2020 | 12:00 AM
      Data Collection as Environmental Enrichment: Automated Behavioral Measurement in Voluntary Home Cage Operant Tasks
      Data Collection as Environmental Enrichment: Automated Behavioral...
      Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...
      Speaker: Jamie Ahloy Dallaire, MSc, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      0
      APR 23, 2020 | 10:30 AM
      Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
      Keynote Presentation: Systematic identification of therapeutic...
      Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
      Speaker: Kris C. Wood, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 15, 2020 | 4:00 PM
      From cell seeding to analysis - Getting the best out of your cell-based assay
      From cell seeding to analysis - Getting the best out of your cell-based...
      DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
      Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
      Sponsored By: Eppendorf, Promega
      19 2
      APR 01, 2020 | 8:00 AM
      An Introduction to Liquid Chromatography-Mass Spectrometry for the Clinical Laboratory
      An Introduction to Liquid Chromatography-Mass Spectrometry for...
      DATE: April 1, 2020 TIME: 8:00am PST The capabilities of liquid chromatography coupled to mass spectrometry make the technology a very attractive tool in clinical laboratory settings. Howeve...
      Speaker: Adam McShane, PhD, DABCC
      11 1
      MAR 25, 2020 | 12:00 AM
      Hemp Seed: Searching for the Present and Future Opportunities
      Hemp Seed: Searching for the Present and Future Opportunities
      Given that the hemp industry in the United States is still nascent, certified seed offers American farmers a way to minimize the risk of growing hemp. For hemp, certification carries additio...
      Speaker: Tom Dermody
      Presented at: Cannabis Sciences Virtual Event Series 2020
      1
      MAR 25, 2020 | 12:00 AM
      Degradant formation in cannabis concentrate aerosols
      Degradant formation in cannabis concentrate aerosols
      Vaporizing cannabis concentrates is increasing in popularity as a potentially healthier alternative to smoking. However, little is known about the chemical profiles of aerosolized concentrat...
      Speaker: Jiries Meehan-Atrash
      Presented at: Cannabis Sciences Virtual Event Series 2020
      1
      MAR 11, 2020 | 3:00 PM
      PANEL: A Team Multi-Disciplinary Approach to Understanding the Neural Circuit Dynamics Underlying Working Memory and Decision-Making
      PANEL: A Team Multi-Disciplinary Approach to Understanding the...
      Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
      Speaker: Carlos Brody, PhD , Ben Engelhard, PhD , Stephen Keeley, PhD , Marlies Oostland, PhD , Lucas Pinto, MD, PhD , Adrian Wanner, PhD , Ilana Witten, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 1:30 PM
      PANEL: Dissecting the circuit logics in the amygdala underlying emotional learning
      PANEL: Dissecting the circuit logics in the amygdala underlying...
      Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
      Speaker: Bo Li , Tianyi Mao , Haining Zhong
      Presented at: Neuroscience Virtual Event Series 2020
      1
    AUG 06, 2020 | 12:00 AM
    Mechanistic basis for the evolution of eukaryotic specialized metabolism
    Mechanistic basis for the evolution of eukaryotic specialized...
    Primary metabolism supports essential chemical processes of living organisms, and is highly conserved among all life forms. In contrast, specialized metabolism contributes to the fitness of...
    Speaker: Jing-Ke Weng, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    Tracking Genome Dynamics in Time and Space
    Tracking Genome Dynamics in Time and Space
    Extrachromosomal circular DNA (eccDNA) comprises products of genomic recombination that cause somatic changes in gene length and sequence. These circular molecules are derived from canonical...
    Speaker: Massa Shoura, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 29, 2020 | 10:00 AM
    Metabolic control of T cell tolerance and antitumor immunity
    Metabolic control of T cell tolerance and antitumor immunity
    Coordination of immune cell metabolic programs with cell fate and state is a fundamental determinant of immune responses. Emerging evidence highlights that the interplay between immune signa...
    Speaker: Hongbo Chi, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 8:00 AM
    High-throughput DNA damage analyses identify synergistic drug combinations to treat malignant brain tumours
    High-throughput DNA damage analyses identify synergistic drug...
    Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
    Speaker: Sachin Katyal, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 7:00 AM
    What intratumoral Tregs eat makes them strong, but vulnerable: a new metabolic intervention for cancer immunotherapy
    What intratumoral Tregs eat makes them strong, but vulnerable:...
    Metabolic reprogramming is critical for governing proper T cell immune responses, including activation, production of effector molecule, migration and differentiation. The metabolic stress T...
    Speaker: Ping-Chih Ho, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
     
     
  • JUL 08, 2020 | 11:00 PM
    Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
    Mass Spectrometry Past and Present - Emerging Technologies and...
    DATE: July 9, 2020 TIME: 2pm SGT, 3pm JST, 4pm AEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not until around 30 to 40...
    Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
    Sponsored By: Waters Corporation
    17
    JUN 25, 2020 | 8:00 AM
    Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
    Mass Spectrometry Past and Present - Emerging Technologies and...
    DATE: June 25, 2020 TIME: 8:00am PDT, 11:00am EDT, 4:00pm BST, 5:00pm CEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not...
    Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
    Sponsored By: Waters Corporation
    34
    JUN 24, 2020 | 10:00 AM
    The Fundamentals of Freeze Drying: Advice from the experts on how to get started
    The Fundamentals of Freeze Drying: Advice from the experts on...
    DATE: June 24, 2020 TIME: 10:00am PT Does your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize your lyo...
    Speaker: Megan Zimerman, B.A. in Biology , Jenny Sprung
    Sponsored By: Labconco
    18 1
    JUN 18, 2020 | 10:30 AM
    Investigating Sensitivity Improvements on the Ultivo TQ using 3D-printed Atmospheric Pressure ion Focusing Devices
    Investigating Sensitivity Improvements on the Ultivo TQ using...
    While the introduction of atmospheric pressure ion sources, such as electrospray ionization, revolutionized the field of mass spectrometry it also introduced new instrumental compilations no...
    Speaker: Patrick Batoon, PhD , Brett Marsh, PhD
    Presented at: Agilent's Virtual Mass Spectacular!
    2
    JUN 17, 2020 | 3:00 PM
    COVID-19: Enrichment and analysis of rare antigen- and virus-specific T cells
    COVID-19: Enrichment and analysis of rare antigen- and virus-specific...
    Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious diseases, immuno-oncology, as well...
    Speaker: Dr. Marcello Stein
    Presented at: Coronavirus Series
    Sponsored By: Miltenyi Biotec
    1
     
     
  • JUN 16, 2020 | 7:00 AM
    Savor the Flavor: Keeping Meat Products Safe with a Veterinary Drug Screening Comprehensive Workflow Solution
    Savor the Flavor: Keeping Meat Products Safe with a Veterinary...
    Veterinary drugs are commonly used chemicals to improve the growth and health outcomes of farm animals raised for human consumption. However, improper use of vet-drugs in animal farming can...
    Speaker: Patrick Batoon, PhD , Siji Joseph
    Presented at: Agilent's Virtual Mass Spectacular!
    4
    JUN 04, 2020 | 2:00 PM
    Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration and Invasion
    Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration...
    In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
    Speaker: KEYNOTE: Claire Brown, PhD
    Presented at: Cell & Developmental Biology Virtual Meeting
    3
    JUN 03, 2020 | 12:00 PM
    Single cell multiomic analysis of T-cell exhaustion
    Single cell multiomic analysis of T-cell exhaustion
    A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
    Speaker: Pratip K. Chattopadhyay
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: BD
    2
    MAY 27, 2020 | 9:00 AM
    Enrichment & analysis of rare antigen & virus-specific T cells
    Enrichment & analysis of rare antigen & virus-specific T cells
    DATE: May 27, 2020 TIME: 9:00am PT Analysis of antigen- and virus-specific T cells is essential to the understanding of fundamental immunological processes in the contexts of e.g. infectious...
    Speaker: Marcello Stein, PhD.
    Sponsored By: Miltenyi Biotec
    20
    MAY 20, 2020 | 12:00 AM
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
    Speaker: Joseph de Rutte
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
     
     
  • MAY 20, 2020 | 12:00 AM
    Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCR™
    Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCR™
    The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
    Speaker: Rémi Dangla
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 14, 2020 | 12:00 AM
    Data Collection as Environmental Enrichment: Automated Behavioral Measurement in Voluntary Home Cage Operant Tasks
    Data Collection as Environmental Enrichment: Automated Behavioral...
    Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...
    Speaker: Jamie Ahloy Dallaire, MSc, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    0
    APR 23, 2020 | 10:30 AM
    Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
    Keynote Presentation: Systematic identification of therapeutic...
    Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
    Speaker: Kris C. Wood, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 15, 2020 | 4:00 PM
    From cell seeding to analysis - Getting the best out of your cell-based assay
    From cell seeding to analysis - Getting the best out of your cell-based...
    DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
    Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
    Sponsored By: Eppendorf, Promega
    19 2
    APR 01, 2020 | 8:00 AM
    An Introduction to Liquid Chromatography-Mass Spectrometry for the Clinical Laboratory
    An Introduction to Liquid Chromatography-Mass Spectrometry for...
    DATE: April 1, 2020 TIME: 8:00am PST The capabilities of liquid chromatography coupled to mass spectrometry make the technology a very attractive tool in clinical laboratory settings. Howeve...
    Speaker: Adam McShane, PhD, DABCC
    11 1
     
     
  • MAR 25, 2020 | 12:00 AM
    Hemp Seed: Searching for the Present and Future Opportunities
    Hemp Seed: Searching for the Present and Future Opportunities
    Given that the hemp industry in the United States is still nascent, certified seed offers American farmers a way to minimize the risk of growing hemp. For hemp, certification carries additio...
    Speaker: Tom Dermody
    Presented at: Cannabis Sciences Virtual Event Series 2020
    1
    MAR 25, 2020 | 12:00 AM
    Degradant formation in cannabis concentrate aerosols
    Degradant formation in cannabis concentrate aerosols
    Vaporizing cannabis concentrates is increasing in popularity as a potentially healthier alternative to smoking. However, little is known about the chemical profiles of aerosolized concentrat...
    Speaker: Jiries Meehan-Atrash
    Presented at: Cannabis Sciences Virtual Event Series 2020
    1
    MAR 11, 2020 | 3:00 PM
    PANEL: A Team Multi-Disciplinary Approach to Understanding the Neural Circuit Dynamics Underlying Working Memory and Decision-Making
    PANEL: A Team Multi-Disciplinary Approach to Understanding the...
    Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
    Speaker: Carlos Brody, PhD , Ben Engelhard, PhD , Stephen Keeley, PhD , Marlies Oostland, PhD , Lucas Pinto, MD, PhD , Adrian Wanner, PhD , Ilana Witten, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 1:30 PM
    PANEL: Dissecting the circuit logics in the amygdala underlying emotional learning
    PANEL: Dissecting the circuit logics in the amygdala underlying...
    Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
    Speaker: Bo Li , Tianyi Mao , Haining Zhong
    Presented at: Neuroscience Virtual Event Series 2020
    1
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