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Gene mutations
Gene mutations describe a change in the DNA sequence that makes up a gene. There are many kinds of gene mutations which have been characterized by scientists. The main categories of mutations are germline mutations, which occur in the gametes (haploid male or female reproductive cells), and somatic mutations, occur in all other cell types. Chromosomal alterations are mutations that change the structure of chromosomes in a variety of ways such as deletion, duplication, insertion, translocation, or inversion of a section of the chromosome. Point mutations include a single nucleotide change within the DNA and these mutations can be classified as silent (the mutation codes for the same amino acid so the change has no effect), missense (the mutation codes for an alternative amino acid), and nonsense (the mutation codes for a premature stop codon). Frameshift mutations occur when the addition or deletion of nucleotide(s) alter the reading frame of the sequence altering all subsequent amino acid coding.
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DEC 19, 2021Cell & Molecular Biology
Though the CRISPR/Cas9 gene editing tool has been tweaked and modified in many ways, it typically edits relatively small ...Written By: Carmen LeitchDEC 16, 2021Cardiology
Congenital heart defects, which a person is born with, impact one in one hundred babies. CHD is a leading cause of death ...Written By: Carmen LeitchDEC 16, 2021Cancer
The incidence of various cancers, including multiple myeloma, colorectal, kidney, and pancreatic cancer, is steadily&nbs ...Written By: Katie KokolusDEC 13, 2021Genetics & Genomics
Late-onset retinal degeneration (L-ORD) is a rare genetic disorder that causes blindness. It's caused by mutations in a ...Written By: Carmen LeitchDEC 12, 2021Drug Discovery & Development
With gene therapy demonstrating an enormous potential to treat a wide range of diseases, Cyagen has added a range of gen ...DEC 01, 2021Genetics & Genomics
Even if the genome of an organism is free of any damaging mutations, the activity of genes has to be controlled very car ...Written By: Carmen LeitchNOV 26, 2021Genetics & Genomics
The biology of organisms can be affected by environmental pressures through the genome. For example, if a genetic mutati ...Written By: Carmen LeitchNOV 23, 2021Clinical & Molecular DX
Cancer is a genetic disease—it stems from specific changes in the DNA sequences of the cancer cell genome. Over th ...Written By: Tara FernandesNOV 22, 2021Health & Medicine
In therapeutic applications, monoclonal antibodies (mAbs) provide highly precise targeting of pathological cells and red ...NOV 21, 2021Microbiology
Zoonosis is a serious health concern, as the COVID-19 pandemic has shown. Viruses that infect one species can acquire ge ...Written By: Carmen LeitchNOV 18, 2021Microbiology
Antibiotics work against bacterial infections, and for years, experts have been warning clinicians and the public to pre ...Written By: Carmen LeitchNOV 15, 2021Genetics & Genomics
The lifespans of vertebrates can vary widely; some live to be about five weeks while others can reach 400 years. As most ...Written By: Carmen LeitchNOV 14, 2021Genetics & Genomics
Cancer drugs have been developed that target an enzyme, Shp2. But that enzyme has a more complex role than we knew.Written By: Carmen LeitchNOV 12, 2021Genetics & Genomics
The UK's 100,000 Genomes Project has now given hundreds of people a diagnosis for their disease. Many of them have been ...Written By: Carmen LeitchNOV 11, 2021Health & Medicine
With more than 15 years of experience in genetic engineering, Cyagen utilizes a highly efficient process, including prop ...NOV 09, 2021Cardiology
Hundreds of thousands of Americans are thought to have dilated cardiomyopathy (DCM), a progressive disorder in which the ...Written By: Carmen LeitchNOV 08, 2021Cancer
Elephants possess two qualities that might make one expect they are at high risk of developing cancer; they are large an ...Written By: Katie KokolusNOV 07, 2021Genetics & Genomics
When the COVID-19 pandemic began to impact the world, researchers everywhere sprang into action. But studying an infecti ...Written By: Carmen LeitchNOV 07, 2021Cell & Molecular Biology
In recent years, researchers have discovered the importance of a kind of antenna that is found on most cells, a structur ...Written By: Carmen LeitchNOV 05, 2021Genetics & Genomics
This photo by Sydney Stringham shows the domestic pigeons that were bred by the researchers for this research.Written By: Carmen LeitchOCT 25, 2021Cell & Molecular Biology
Labroots virtual events are a great place to share research and learn about others work. These events feature participan ...Written By: Carmen LeitchOCT 24, 2021Genetics & Genomics
Beta cells in the pancreas produce the insulin our body needs to properly regulate blood sugar. Diabetes results when th ...Written By: Carmen LeitchOCT 20, 2021Genetics & Genomics
In the human eye, a space called the anterior chamber sits in between the cornea, which is a clear layer in the front of ...Written By: Carmen LeitchOCT 18, 2021Genetics & Genomics
For decades, scientists have been trying to find ways to cure disorders that can be traced back to an error in one gene. ...Written By: Carmen Leitch
DEC 19, 2021
Cell & Molecular Biology
Though the CRISPR/Cas9 gene editing tool has been tweaked and modified in many ways, it typically edits relatively small
...
Written By:
Carmen Leitch
DEC 16, 2021
Cardiology
Congenital heart defects, which a person is born with, impact one in one hundred babies. CHD is a leading cause of death
...
Written By:
Carmen Leitch
DEC 16, 2021
Cancer
The incidence of various cancers, including multiple myeloma, colorectal, kidney, and pancreatic cancer, is steadily&nbs
...
Written By:
Katie Kokolus
DEC 13, 2021
Genetics & Genomics
Late-onset retinal degeneration (L-ORD) is a rare genetic disorder that causes blindness. It's caused by mutations in a
...
Written By:
Carmen Leitch
DEC 12, 2021
Drug Discovery & Development
With gene therapy demonstrating an enormous potential to treat a wide range of diseases, Cyagen has added a range of gen
...
DEC 01, 2021
Genetics & Genomics
Even if the genome of an organism is free of any damaging mutations, the activity of genes has to be controlled very car
...
Written By:
Carmen Leitch
NOV 26, 2021
Genetics & Genomics
The biology of organisms can be affected by environmental pressures through the genome. For example, if a genetic mutati
...
Written By:
Carmen Leitch
NOV 23, 2021
Clinical & Molecular DX
Cancer is a genetic disease—it stems from specific changes in the DNA sequences of the cancer cell genome. Over th
...
Written By:
Tara Fernandes
NOV 22, 2021
Health & Medicine
In therapeutic applications, monoclonal antibodies (mAbs) provide highly precise targeting of pathological cells and red
...
NOV 21, 2021
Microbiology
Zoonosis is a serious health concern, as the COVID-19 pandemic has shown. Viruses that infect one species can acquire ge
...
Written By:
Carmen Leitch
NOV 18, 2021
Microbiology
Antibiotics work against bacterial infections, and for years, experts have been warning clinicians and the public to pre
...
Written By:
Carmen Leitch
NOV 15, 2021
Genetics & Genomics
The lifespans of vertebrates can vary widely; some live to be about five weeks while others can reach 400 years. As most
...
Written By:
Carmen Leitch
NOV 14, 2021
Genetics & Genomics
Cancer drugs have been developed that target an enzyme, Shp2. But that enzyme has a more complex role than we knew.
Written By:
Carmen Leitch
NOV 12, 2021
Genetics & Genomics
The UK's 100,000 Genomes Project has now given hundreds of people a diagnosis for their disease. Many of them have been
...
Written By:
Carmen Leitch
NOV 11, 2021
Health & Medicine
With more than 15 years of experience in genetic engineering, Cyagen utilizes a highly efficient process, including prop
...
NOV 09, 2021
Cardiology
Hundreds of thousands of Americans are thought to have dilated cardiomyopathy (DCM), a progressive disorder in which the
...
Written By:
Carmen Leitch
NOV 08, 2021
Cancer
Elephants possess two qualities that might make one expect they are at high risk of developing cancer; they are large an
...
Written By:
Katie Kokolus
NOV 07, 2021
Genetics & Genomics
When the COVID-19 pandemic began to impact the world, researchers everywhere sprang into action. But studying an infecti
...
Written By:
Carmen Leitch
NOV 07, 2021
Cell & Molecular Biology
In recent years, researchers have discovered the importance of a kind of antenna that is found on most cells, a structur
...
Written By:
Carmen Leitch
NOV 05, 2021
Genetics & Genomics
This photo by Sydney Stringham shows the domestic pigeons that were bred by the researchers for this research.
Written By:
Carmen Leitch
OCT 25, 2021
Cell & Molecular Biology
Labroots virtual events are a great place to share research and learn about others work. These events feature participan
...
Written By:
Carmen Leitch
OCT 24, 2021
Genetics & Genomics
Beta cells in the pancreas produce the insulin our body needs to properly regulate blood sugar. Diabetes results when th
...
Written By:
Carmen Leitch
OCT 20, 2021
Genetics & Genomics
In the human eye, a space called the anterior chamber sits in between the cornea, which is a clear layer in the front of
...
Written By:
Carmen Leitch
OCT 18, 2021
Genetics & Genomics
For decades, scientists have been trying to find ways to cure disorders that can be traced back to an error in one gene.
...
Written By:
Carmen Leitch