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    Hedgehog signaling

    The Hedgehog signaling pathway is an integral regulator in growth and development of animals. Hedgehog signaling has roles in embryonic development and adults. Disruption of the signaling pathway during gestation can produce severe birth defects. Activation of the pathway can convert adult stem cells to cancer stem cells and activation is thus associated with the development of several cancers, including brain, lung, prostate, and skin cancers.

    What's Popular in Hedgehog signaling

    Trending News

    • OCT 27, 2023
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      Written By: Carmen Leitch
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      JAN 26, 2023
      Neuroscience
      Mechanisms Underlying Tourette Syndrome Revealed by Brain Organoids
      Mechanisms Underlying Tourette Syndrome Revealed by Brain Organoids
      Tourette syndrome (TS) is a nervous system disorder that causes sudden movements, twitches, or sounds that are repeated. ...
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      SEP 11, 2020
      Immunology
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      Study Reveals Tumor Defense Mechanism... And How to Beat It
        P53 is an infamous process gene at the core of the development of tumors.  When P53  functional, it pau ...
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      AUG 31, 2020
      Cancer
      Targeting Your Inner Hedgehog to Fight Chemoresistance in Colorectal Cancer
      Targeting Your Inner Hedgehog to Fight Chemoresistance in Colorectal Cancer
      Chemoresistance is a serious problem for many cancer therapies. Solutions to this problem are harder to come by than the ...
      Written By: Jasper Cantrell
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      SEP 20, 2019
      Drug Discovery & Development
      Leukemia Drug Effective for Treating Childhood Brain Cancer
      Leukemia Drug Effective for Treating Childhood Brain Cancer
      Scientists at the University of California-San Diego have found that a chronic myeloid leukemia drug was found to treat ...
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    OCT 27, 2023
    Genetics & Genomics
    A Genetic Cause for Some Brain Tumors is Revealed
    A Genetic Cause for Some Brain Tumors is Revealed
    Meningiomas are tumors that form in the central nervous system, and are the most common type of brain and spinal cord tu ...
    Written By: Carmen Leitch
    4
    JAN 26, 2023
    Neuroscience
    Mechanisms Underlying Tourette Syndrome Revealed by Brain Organoids
    Mechanisms Underlying Tourette Syndrome Revealed by Brain Organoids
    Tourette syndrome (TS) is a nervous system disorder that causes sudden movements, twitches, or sounds that are repeated. ...
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    1
    SEP 11, 2020
    Immunology
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    Study Reveals Tumor Defense Mechanism... And How to Beat It
      P53 is an infamous process gene at the core of the development of tumors.  When P53  functional, it pau ...
    Written By: Amanda Mikyska
    1
     
     
    AUG 31, 2020
    Cancer
    Targeting Your Inner Hedgehog to Fight Chemoresistance in Colorectal Cancer
    Targeting Your Inner Hedgehog to Fight Chemoresistance in Colorectal Cancer
    Chemoresistance is a serious problem for many cancer therapies. Solutions to this problem are harder to come by than the ...
    Written By: Jasper Cantrell
    1
    SEP 20, 2019
    Drug Discovery & Development
    Leukemia Drug Effective for Treating Childhood Brain Cancer
    Leukemia Drug Effective for Treating Childhood Brain Cancer
    Scientists at the University of California-San Diego have found that a chronic myeloid leukemia drug was found to treat ...
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    SEP 01, 2018
    Technology
    Cryo-EM for Precise Molecular Structures
    Cryo-EM for Precise Molecular Structures
    The Hedgehog signaling pathway is known to transmit information to embryonic cells. However, insufficient signaling duri ...
    Written By: Nouran Amin
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    JUN 08, 2017
    Cell & Molecular Biology
    Important Component of Sonic Hedgehog Pathway is ID'ed
    Important Component of Sonic Hedgehog Pathway is ID'ed
    Researchers have learned more about an important cellular signaling pathway that has been linked to cancer and genetic d ...
    Written By: Carmen Leitch
    2
    MAR 04, 2016
    Cell & Molecular Biology
    ‘Dial' on astrocytes means brain cells can be adjusted
    ‘Dial' on astrocytes means brain cells can be adjusted
    Astrocytes are star-shaped cells in our brain that surround neurons and neural circuits, protecting them from injury and ...
    Written By: Futurity (futurity.org)
    5
    SEP 09, 2015
    Space & Astronomy
    Hedgehog: Perfectly Designed For Microgravity Exploration, Part II
    Hedgehog: Perfectly Designed For Microgravity Exploration, Part II
    Part I of this article described a new kind of cube-shaped probe that NASA’s JPL and Stanford University are desig ...
    Written By: Andrew J. Dunlop
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    • FEB 23, 2022 | 3:00 PM
      Genetically Engineered Custom Cell Lines for Pre-Clinical Research and Biomanufacturing
      Genetically Engineered Custom Cell Lines for Pre-Clinical Research...
      Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
      Speaker: Stacey Ward, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      Sponsored By: MilliporeSigma
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      JUN 02, 2021 | 12:00 PM
      Genetically-Engineered Immuno-oncology Cell Lines and Services for Early Drug Discovery Research and Preclinical Manufacturing
      Genetically-Engineered Immuno-oncology Cell Lines and Services...
      Gene editing experts within MilliporeSigma’s Cell Design Studio™ provide premier custom cell line engineering services to create and deliver unique cell-based assays tailored for...
      Speaker: Stacey Ward, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2021
      Sponsored By: MilliporeSigma
      2
      OCT 28, 2020 | 7:00 AM
      Guiding pancreatic cancer therapy by individualized epigenetics
      Guiding pancreatic cancer therapy by individualized epigenetics
      Date: October 28, 2020 Time: 7:00am (PDT), 10:00am (EDT) Although chemotherapy remains the mainstay of systemic therapy, a large number of cancer patients fail to respond to it. About half o...
      Speaker: Surajit Dhara, Ph.D. , Valentina Maran, Ph.D.
      Sponsored By: Agilent
      12
    FEB 23, 2022 | 3:00 PM
    Genetically Engineered Custom Cell Lines for Pre-Clinical Research and Biomanufacturing
    Genetically Engineered Custom Cell Lines for Pre-Clinical Research...
    Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
    Speaker: Stacey Ward, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    Sponsored By: MilliporeSigma
    1
    JUN 02, 2021 | 12:00 PM
    Genetically-Engineered Immuno-oncology Cell Lines and Services for Early Drug Discovery Research and Preclinical Manufacturing
    Genetically-Engineered Immuno-oncology Cell Lines and Services...
    Gene editing experts within MilliporeSigma’s Cell Design Studio™ provide premier custom cell line engineering services to create and deliver unique cell-based assays tailored for...
    Speaker: Stacey Ward, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2021
    Sponsored By: MilliporeSigma
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    OCT 28, 2020 | 7:00 AM
    Guiding pancreatic cancer therapy by individualized epigenetics
    Guiding pancreatic cancer therapy by individualized epigenetics
    Date: October 28, 2020 Time: 7:00am (PDT), 10:00am (EDT) Although chemotherapy remains the mainstay of systemic therapy, a large number of cancer patients fail to respond to it. About half o...
    Speaker: Surajit Dhara, Ph.D. , Valentina Maran, Ph.D.
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    Virtual Events

    • FEB 18, 2026  | 6:00 AM PST
      Drug Discovery & Development Virtual Event Series 2026
      Drug Discovery & Development Virtual Event Series 2026
      Experience the forefront of pharmaceutical innovation as Labroots and the Drug Discovery and Development planning committee host the 9th Annual Event in the Drug Discovery & Development...
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      FEB 19, 2025  | 6:00 AM PST
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      Drug Discovery & Development Virtual Event Series 2025
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      FEB 21, 2024  | 5:30 AM PST
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      FEB 22, 2023  | 5:30 AM PST
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      Drug Discovery & Development Virtual Event Series 2023
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      FEB 23, 2022  | 5:30 AM PST
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      Drug Discovery & Development Virtual Event Series 2022
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    FEB 18, 2026  | 6:00 AM PST
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    Drug Discovery & Development Virtual Event Series 2023
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    JUN 02, 2021  | 5:30 AM PDT
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    Immuno-Oncology Virtual Event Series 2021
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    OCT 10, 2018  | 6:00 AM PDT
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