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    Hepatic models

    Hepatic models are pre-clinical systems used to research diseases involving the liver. Examples of hepatic models include "liver-on-a-chip", a microfluidic replica or the liver microenvironment, and liver organoids, a collection of various cells that display liver-specific functions and structural organization. Hepatic models have been used for disease modeling, drug development, and clinical application.

    Webinars

    • MAY 17, 2017 | 10:30 AM
      WEBINAR: Improved differentiation of stem cell-derived neurons and downstream applications through the reduction of progenitor proliferation with CultureOne™ Supplement
      WEBINAR: Improved differentiation of stem cell-derived neurons...
      DATE: May 17, 2017TIME: 10:30am PT, 1:30pm ETNeurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and d...
      Speaker: David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      MAY 01, 2017 | 8:00 AM
      Improved differentiation of stem cell-derived neurons and downstream applications through the reduction of progenitor proliferation with CultureOne™ Supplement
      Improved differentiation of stem cell-derived neurons and downstream...
      Neurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and drug screening.  Human PSCs derived neural stem...
      Speaker: David Kuninger, PhD
      Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
      1
      FEB 08, 2017 | 3:00 PM
      Management of a research colony of woodchucks (Marmota monax)
      Management of a research colony of woodchucks (Marmota monax)
      DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETThe Eastern woodchuck (Marmota monax) is a large, burrowing rodent with native territories throughout parts of the US and Canada. Woodchu...
      Speaker: Margaret (Peg) Batchelder, DVM, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      SEP 08, 2016 | 12:00 PM
      Plant Viruses: Everywhere and Often Mutualistic
      Plant Viruses: Everywhere and Often Mutualistic
       Virus Ecology is a field that is gaining momentum, fueled in part by metagenomic studies from many environments previously ignored. Biodiversity studies of plant viruses show that they...
      Speaker: Marilyn Roossinck, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      4
      AUG 30, 2016 | 8:00 AM
      Directed differentiation of induced pluripotent stem cells to hepatic stellate cells
      Directed differentiation of induced pluripotent stem cells to...
      In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-...
      Speaker: Pau Sancho Bru, PhD
      Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
      1
      AUG 30, 2016 | 8:00 AM
      Improved differentiation of human pluripotent stem cell-derived neurons through reduction of progenitor proliferation: impact on downstream applications
      Improved differentiation of human pluripotent stem cell-derived...
      Neurons derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are excellent resources for disease modeling and d...
      Speaker: David Kuninger, PhD
      Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      1
      SEP 30, 2015 | 12:00 PM
      Modeling and dissecting hepatocellular carcinoma dissemination
      Modeling and dissecting hepatocellular carcinoma dissemination
      Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
      Speaker: Brian Lewis, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      FEB 06, 2014 | 6:00 AM
      Use of Dried Blood Spot Samples in Serological Testing of Rodents
      Use of Dried Blood Spot Samples in Serological Testing of Rodents
      The utility of dried blood spot (DBS) sampling technology for rodent colony health monitoring was investigated using a two-tiered approach. In the first approach, groups of mice and rats were...
      Speaker: Matthew H Myles, DVM, PhD, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
    MAY 17, 2017 | 10:30 AM
    WEBINAR: Improved differentiation of stem cell-derived neurons and downstream applications through the reduction of progenitor proliferation with CultureOne™ Supplement
    WEBINAR: Improved differentiation of stem cell-derived neurons...
    DATE: May 17, 2017TIME: 10:30am PT, 1:30pm ETNeurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and d...
    Speaker: David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    MAY 01, 2017 | 8:00 AM
    Improved differentiation of stem cell-derived neurons and downstream applications through the reduction of progenitor proliferation with CultureOne™ Supplement
    Improved differentiation of stem cell-derived neurons and downstream...
    Neurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and drug screening.  Human PSCs derived neural stem...
    Speaker: David Kuninger, PhD
    Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
    1
    FEB 08, 2017 | 3:00 PM
    Management of a research colony of woodchucks (Marmota monax)
    Management of a research colony of woodchucks (Marmota monax)
    DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETThe Eastern woodchuck (Marmota monax) is a large, burrowing rodent with native territories throughout parts of the US and Canada. Woodchu...
    Speaker: Margaret (Peg) Batchelder, DVM, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    SEP 08, 2016 | 12:00 PM
    Plant Viruses: Everywhere and Often Mutualistic
    Plant Viruses: Everywhere and Often Mutualistic
     Virus Ecology is a field that is gaining momentum, fueled in part by metagenomic studies from many environments previously ignored. Biodiversity studies of plant viruses show that they...
    Speaker: Marilyn Roossinck, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    4
    AUG 30, 2016 | 8:00 AM
    Directed differentiation of induced pluripotent stem cells to hepatic stellate cells
    Directed differentiation of induced pluripotent stem cells to...
    In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-...
    Speaker: Pau Sancho Bru, PhD
    Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
    1
     
     
  • AUG 30, 2016 | 8:00 AM
    Improved differentiation of human pluripotent stem cell-derived neurons through reduction of progenitor proliferation: impact on downstream applications
    Improved differentiation of human pluripotent stem cell-derived...
    Neurons derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are excellent resources for disease modeling and d...
    Speaker: David Kuninger, PhD
    Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    1
    SEP 30, 2015 | 12:00 PM
    Modeling and dissecting hepatocellular carcinoma dissemination
    Modeling and dissecting hepatocellular carcinoma dissemination
    Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
    Speaker: Brian Lewis, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    FEB 06, 2014 | 6:00 AM
    Use of Dried Blood Spot Samples in Serological Testing of Rodents
    Use of Dried Blood Spot Samples in Serological Testing of Rodents
    The utility of dried blood spot (DBS) sampling technology for rodent colony health monitoring was investigated using a two-tiered approach. In the first approach, groups of mice and rats were...
    Speaker: Matthew H Myles, DVM, PhD, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
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