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    Histone Modification

    A histone modification is a covalent post-translational modification (PTM) to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. The PTMs made to histones can impact gene expression by altering chromatin structure or recruiting histone modifiers. Histone proteins act to package DNA, which wraps around the eight histones, into chromosomes. Histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair.

    Webinars

    • OCT 24, 2023 | 10:00 AM
      An epic advance in epigenomics: Automated CUT&RUN enables chromatin profiling for scaled research & drug discovery applications
      An epic advance in epigenomics: Automated CUT&RUN enables chromatin...
      Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
      Speaker: Andrea Johnstone, Ph.D. , Lori Euler
      Sponsored By: Beckman Coulter Life Sciences
      30
      MAY 31, 2023 | 11:00 AM
      Unveiling insights: Leveraging single-cell transcriptomics and epigenomics for biomarker discovery
      Unveiling insights: Leveraging single-cell transcriptomics and...
      Date: May 31, 2023 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CET) Single-cell genomics has facilitated the understanding of mechanisms involved in various biological processes such as tumor...
      Speaker: Dr. Derek Janssens, PhD , Dr. Ilaria Iacobucci, PhD
      Sponsored By: Takara Bio
      21
      MAY 11, 2021 | 10:00 AM
      Secure Your Next Great Discovery
      Secure Your Next Great Discovery
      Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
      Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      8
      OCT 29, 2020 | 6:00 AM
      Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
      Single-cell sequencing to investigate epigenetic mechanisms in...
      Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
      Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
      Sponsored By: Illumina, Dolomite Bio
      15
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      JUL 29, 2020 | 1:00 PM
      Using quantitative imaging microscopy to explore and target the molecular origins of cancer
      Using quantitative imaging microscopy to explore and target the...
      The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
      Speaker: Kirk McManus, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 12:00 PM
      Linking Cancer Metabolism to Neurodegeneration
      Linking Cancer Metabolism to Neurodegeneration
      The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
      Speaker: Navdeep S. Chandel PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      3
      JUN 03, 2020 | 2:00 AM
      A Mitotic Error Code
      A Mitotic Error Code
      Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
      Speaker: KEYNOTE: Helder Maiato, PhD
      Presented at: Cell & Developmental Biology Virtual Meeting
      3
      MAY 14, 2020 | 2:15 PM
      First Experience from New World of Easy NGS - Ion Torrent Genexus Workflow
      First Experience from New World of Easy NGS - Ion Torrent Genexus...
      In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
      Speaker: Philip Jermann, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      2
      MAY 14, 2020 | 2:15 PM
      First Experience from New World of Easy NGS - Ion Torrent Genexus Workflow
      First Experience from New World of Easy NGS - Ion Torrent Genexus...
      In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
      Speaker: Philip Jermann, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      8
      APR 29, 2020 | 6:00 AM
      High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
      High-Throughput assessment of ChIP-grade capability with Luminex...
      Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
      Speaker: Michael-Christopher Keogh, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      MAY 03, 2018 | 11:00 AM
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
      Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
      DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
      Speaker: Sisi Li
      Sponsored By: Covaris
      5 2
      OCT 12, 2017 | 1:30 PM
      Metabolic Regulation of Cell Fate Decisions
      Metabolic Regulation of Cell Fate Decisions
      The deposition and removal of DNA and histone modifications depends on the availability of specific metabolites, suggesting that cellular metabolic pathways may dynamically regulate chromatin...
      Speaker: Lydia Finley
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      Sponsored By: Agilent
      2
      APR 14, 2017 | 10:00 AM
      WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated with Age and Dietary Restriction using Targeted MS and Untargeted LC-MS Lipidomics Approaches
      WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated...
      DATE: April 14, 2017TIME: 10:00AM PST, 1:00PM ET The study presented will represent the most comprehensive characterization of lipid changes in the context of aging and DR to d...
      Speaker: Kévin Contrepois , PhD
      Sponsored By: SCIEX
      6 3
      JAN 17, 2017 | 8:00 AM
      Regulation of Bivalent Domains by Histone Modifications
      Regulation of Bivalent Domains by Histone Modifications
      Bivalent domains are thought to be controversial, yet crucial,  regulatory hubs in the differentiation of stem cells. Listen in as  Dr Philipp Voigt of the Wellcome Trust Centre for...
      Speaker: Philipp Voigt, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      4
      NOV 23, 2016 | 8:00 AM
      Studying Kinetics of Chromatin Assembly with SWATH-MS
      Studying Kinetics of Chromatin Assembly with SWATH-MS
      DATE: November 23rd, 2016TIME: 8:00AM PT, 11:00AM ETThe structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
      Speaker: Moritz Voelker-Albert , Andreas Schmidt
      Sponsored By: SCIEX OMICS, SCIEX OMICS
      24
      APR 11, 2016 | 9:00 AM
      WEBINAR: The epigenome in normal human placental development and its dysregulation in preeclampsia
      WEBINAR: The epigenome in normal human placental development and...
      9:00 AM PT, 11:00 AM CT, 12:00 PM ET Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
      Speaker: Peter Jones, Ph.D., D.Sc. , Nandor Than, MD, PhD
      Sponsored By: Zymo Research, Zymo Research
      10 4
      OCT 16, 2013 | 7:00 AM
      Metabolic reprogramming: links to the epigenome
      Metabolic reprogramming: links to the epigenome
      Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of can...
      Speaker: Kathryn E Wellen, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      108
    OCT 24, 2023 | 10:00 AM
    An epic advance in epigenomics: Automated CUT&RUN enables chromatin profiling for scaled research & drug discovery applications
    An epic advance in epigenomics: Automated CUT&RUN enables chromatin...
    Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
    Speaker: Andrea Johnstone, Ph.D. , Lori Euler
    Sponsored By: Beckman Coulter Life Sciences
    30
    MAY 31, 2023 | 11:00 AM
    Unveiling insights: Leveraging single-cell transcriptomics and epigenomics for biomarker discovery
    Unveiling insights: Leveraging single-cell transcriptomics and...
    Date: May 31, 2023 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CET) Single-cell genomics has facilitated the understanding of mechanisms involved in various biological processes such as tumor...
    Speaker: Dr. Derek Janssens, PhD , Dr. Ilaria Iacobucci, PhD
    Sponsored By: Takara Bio
    21
    MAY 11, 2021 | 10:00 AM
    Secure Your Next Great Discovery
    Secure Your Next Great Discovery
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    8
    OCT 29, 2020 | 6:00 AM
    Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
    Single-cell sequencing to investigate epigenetic mechanisms in...
    Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
    Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
    Sponsored By: Illumina, Dolomite Bio
    15
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
     
     
  • JUL 29, 2020 | 1:00 PM
    Using quantitative imaging microscopy to explore and target the molecular origins of cancer
    Using quantitative imaging microscopy to explore and target the...
    The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
    Speaker: Kirk McManus, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 12:00 PM
    Linking Cancer Metabolism to Neurodegeneration
    Linking Cancer Metabolism to Neurodegeneration
    The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
    Speaker: Navdeep S. Chandel PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    3
    JUN 03, 2020 | 2:00 AM
    A Mitotic Error Code
    A Mitotic Error Code
    Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
    Speaker: KEYNOTE: Helder Maiato, PhD
    Presented at: Cell & Developmental Biology Virtual Meeting
    3
    MAY 14, 2020 | 2:15 PM
    First Experience from New World of Easy NGS - Ion Torrent Genexus Workflow
    First Experience from New World of Easy NGS - Ion Torrent Genexus...
    In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
    Speaker: Philip Jermann, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    2
    MAY 14, 2020 | 2:15 PM
    First Experience from New World of Easy NGS - Ion Torrent Genexus Workflow
    First Experience from New World of Easy NGS - Ion Torrent Genexus...
    In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
    Speaker: Philip Jermann, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    8
     
     
  • APR 29, 2020 | 6:00 AM
    High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
    High-Throughput assessment of ChIP-grade capability with Luminex...
    Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
    Speaker: Michael-Christopher Keogh, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    MAY 03, 2018 | 11:00 AM
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue - An Investigation of How Stress Alters 5hmC by Mediating Transcription Factor (TF) Binding
    Performing ChIP Using Low Amounts of Frozen Mouse Brain Tissue...
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    Speaker: Sisi Li
    Sponsored By: Covaris
    5 2
    OCT 12, 2017 | 1:30 PM
    Metabolic Regulation of Cell Fate Decisions
    Metabolic Regulation of Cell Fate Decisions
    The deposition and removal of DNA and histone modifications depends on the availability of specific metabolites, suggesting that cellular metabolic pathways may dynamically regulate chromatin...
    Speaker: Lydia Finley
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    Sponsored By: Agilent
    2
    APR 14, 2017 | 10:00 AM
    WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated with Age and Dietary Restriction using Targeted MS and Untargeted LC-MS Lipidomics Approaches
    WEBINAR: Comparative Analysis of Plasma Lipid Alterations Associated...
    DATE: April 14, 2017TIME: 10:00AM PST, 1:00PM ET The study presented will represent the most comprehensive characterization of lipid changes in the context of aging and DR to d...
    Speaker: Kévin Contrepois , PhD
    Sponsored By: SCIEX
    6 3
    JAN 17, 2017 | 8:00 AM
    Regulation of Bivalent Domains by Histone Modifications
    Regulation of Bivalent Domains by Histone Modifications
    Bivalent domains are thought to be controversial, yet crucial,  regulatory hubs in the differentiation of stem cells. Listen in as  Dr Philipp Voigt of the Wellcome Trust Centre for...
    Speaker: Philipp Voigt, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    4
     
     
  • NOV 23, 2016 | 8:00 AM
    Studying Kinetics of Chromatin Assembly with SWATH-MS
    Studying Kinetics of Chromatin Assembly with SWATH-MS
    DATE: November 23rd, 2016TIME: 8:00AM PT, 11:00AM ETThe structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
    Speaker: Moritz Voelker-Albert , Andreas Schmidt
    Sponsored By: SCIEX OMICS, SCIEX OMICS
    24
    APR 11, 2016 | 9:00 AM
    WEBINAR: The epigenome in normal human placental development and its dysregulation in preeclampsia
    WEBINAR: The epigenome in normal human placental development and...
    9:00 AM PT, 11:00 AM CT, 12:00 PM ET Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
    Speaker: Peter Jones, Ph.D., D.Sc. , Nandor Than, MD, PhD
    Sponsored By: Zymo Research, Zymo Research
    10 4
    OCT 16, 2013 | 7:00 AM
    Metabolic reprogramming: links to the epigenome
    Metabolic reprogramming: links to the epigenome
    Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of can...
    Speaker: Kathryn E Wellen, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    108
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