Histone Modification
A histone modification is a covalent post-translational modification (PTM) to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. The PTMs made to histones can impact gene expression by altering chromatin structure or recruiting histone modifiers. Histone proteins act to package DNA, which wraps around the eight histones, into chromosomes. Histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair.
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MAR 21, 2021Genetics & Genomics
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NOV 20, 2016A study published in Cell demonstrated how the brains of patients with different kinds of autism spectrum disorder (ASD) ...Written By: Carmen Leitch
MAR 21, 2021
Genetics & Genomics
MAR 21, 2021
We know that there are certain substances that can harm a developing fetus, like alcohol or lead. Some health conditions
...
Written By:
Carmen Leitch
MAR 01, 2021
Cardiology
MAR 01, 2021
Researchers have used a mouse model to show that heart problems can lead to disruptions in gene activity in the memory c
...
Written By:
Carmen Leitch
FEB 16, 2021
Clinical & Molecular DX
FEB 16, 2021
Taking a sample of tissue called a biopsy from an organ suspected of harboring a pathology is a common diagnostic practi
...
Written By:
Tara Fernandez
FEB 08, 2021
Genetics & Genomics
FEB 08, 2021
While the human genome was sequenced many years ago, there was so much to learn about it beyond just its sequence, like
...
Written By:
Carmen Leitch
JAN 24, 2021
Drug Discovery & Development
JAN 24, 2021
Cells in our body share the same genes. But how those genes are expressed can dictate the fate of a cell. For
...
Written By:
Nouran Amin
DEC 10, 2020
Genetics & Genomics
DEC 10, 2020
It's thought that by the year 2060, there will be 14 million Americans living with Alzheimer's disease.
Written By:
Carmen Leitch
DEC 09, 2020
Genetics & Genomics
DEC 09, 2020
Glyphosate is a common weed-killing chemical used in agriculture, and it may be best known as the active ingredient in R
...
Written By:
Carmen Leitch
NOV 22, 2020
Cell & Molecular Biology
NOV 22, 2020
ChIP-Seq is a tool for analyzing the interactions between DNA and the proteins that bind to it, which influences gene ac
...
Written By:
Carmen Leitch
AUG 12, 2020
Cancer
AUG 12, 2020
A first-of-its-kind study provides a comprehensive genomic study of cervical cancers in sub-Saharan Africa. Sub-Saharan
...
Written By:
Kathryn DeMuth Sullivan
AUG 03, 2020
Cancer
AUG 03, 2020
New research is published by scientists at Dana-Farber Cancer Institute have discovered new information that may help pa
...
Written By:
Kathryn DeMuth Sullivan
APR 14, 2020
Cell & Molecular Biology
APR 14, 2020
Proteins usually work together, whether as part of a pathway or a complex, and there are several ways to investigate pro
...
Written By:
Carmen Leitch
APR 03, 2020
Genetics & Genomics
APR 03, 2020
Less than a millisecond after a cell is stretched out, genes are activated, which will result in the production of prote
...
Written By:
Carmen Leitch
OCT 31, 2019
Cancer
OCT 31, 2019
In a recent issue of Nature, the findings of one study made a particularly big splash: how and why cancer cells use ener
...
Written By:
Kathryn DeMuth Sullivan
OCT 24, 2019
Neuroscience
OCT 24, 2019
For a recovering alcoholic, walking past a familiar bar or attending social events are often challenging situations. In
...
Written By:
Dr. Nina Lichtenberg
SEP 21, 2019
Cell & Molecular Biology
SEP 21, 2019
Every cell type has to carefully control which genes are expressed, and new research has learned more about that process
...
Written By:
Carmen Leitch
JAN 22, 2019
Genetics & Genomics
JAN 22, 2019
Scientists have taken a close look at what happens on the molecular level when DNA is inserted into the genome of a plan
...
Written By:
Carmen Leitch
OCT 23, 2018
Genetics & Genomics
OCT 23, 2018
We are born with a genome that doesn't change, but small modifications can be made to that genetic material throughout o
...
Written By:
Carmen Leitch
JUN 26, 2018
Cancer
JUN 26, 2018
An introduction to genomics, transcriptomics, proteomics, epigenomics, and metabolomics.
Written By:
Mauri Brueggeman
MAY 21, 2018
Cancer
MAY 21, 2018
Epigenetics is defined and outlined as important in gene expression and a possible cause for cancer development & as a t
...
Written By:
Mauri Brueggeman
MAY 17, 2018
Immunology
MAY 17, 2018
A detailed investigation into the epigenome of rheumatoid arthritis (RA) patients revealed unexpected similarities betwe
...
Written By:
Kara Marker
DEC 17, 2017
Drug Discovery & Development
AUG 16, 2017
Microbiology
AUG 16, 2017
Researchers at the National Institute of Allergy and Infectious Disease knew that some viruses - herpes simplex virus, f
...
Written By:
Kerry Evans
JAN 31, 2017
Genetics & Genomics
NOV 20, 2016
Cell & Molecular Biology
NOV 20, 2016
A study published in Cell demonstrated how the brains of patients with different kinds of autism spectrum disorder (ASD)
...
Written By:
Carmen Leitch
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