Histone Modification
A histone modification is a covalent post-translational modification (PTM) to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. The PTMs made to histones can impact gene expression by altering chromatin structure or recruiting histone modifiers. Histone proteins act to package DNA, which wraps around the eight histones, into chromosomes. Histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair.
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AUG 23, 2021
Cancer
AUG 23, 2021
Immunotherapies are emerging as a promising strategy for the treatment of late-stage cancers which currently have m
...
Written By:
Katie Kokolus
JUN 28, 2021
Genetics & Genomics
JUN 28, 2021
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...
Written By:
Carmen Leitch
JUN 20, 2021
Genetics & Genomics
JUN 20, 2021
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...
Written By:
Carmen Leitch
MAR 21, 2021
Genetics & Genomics
MAR 21, 2021
We know that there are certain substances that can harm a developing fetus, like alcohol or lead. Some health conditions
...
Written By:
Carmen Leitch
MAR 01, 2021
Cardiology
MAR 01, 2021
Researchers have used a mouse model to show that heart problems can lead to disruptions in gene activity in the memory c
...
Written By:
Carmen Leitch
FEB 16, 2021
Clinical & Molecular DX
FEB 16, 2021
Taking a sample of tissue called a biopsy from an organ suspected of harboring a pathology is a common diagnostic practi
...
Written By:
Tara Fernandez
FEB 08, 2021
Genetics & Genomics
FEB 08, 2021
While the human genome was sequenced many years ago, there was so much to learn about it beyond just its sequence, like
...
Written By:
Carmen Leitch
JAN 24, 2021
Drug Discovery & Development
JAN 24, 2021
Cells in our body share the same genes. But how those genes are expressed can dictate the fate of a cell. For
...
Written By:
Nouran Amin
DEC 10, 2020
Genetics & Genomics
DEC 10, 2020
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Written By:
Carmen Leitch
DEC 09, 2020
Genetics & Genomics
DEC 09, 2020
Glyphosate is a common weed-killing chemical used in agriculture, and it may be best known as the active ingredient in R
...
Written By:
Carmen Leitch
NOV 22, 2020
Cell & Molecular Biology
NOV 22, 2020
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...
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AUG 12, 2020
Cancer
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...
Written By:
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AUG 03, 2020
Cancer
AUG 03, 2020
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...
Written By:
Kathryn DeMuth Sullivan
APR 14, 2020
Cell & Molecular Biology
APR 14, 2020
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...
Written By:
Carmen Leitch
APR 03, 2020
Genetics & Genomics
APR 03, 2020
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...
Written By:
Carmen Leitch
OCT 31, 2019
Cancer
OCT 31, 2019
In a recent issue of Nature, the findings of one study made a particularly big splash: how and why cancer cells use ener
...
Written By:
Kathryn DeMuth Sullivan
OCT 24, 2019
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OCT 24, 2019
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...
Written By:
Dr. Nina Lichtenberg
SEP 21, 2019
Cell & Molecular Biology
SEP 21, 2019
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...
Written By:
Carmen Leitch
JAN 22, 2019
Genetics & Genomics
JAN 22, 2019
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...
Written By:
Carmen Leitch
OCT 23, 2018
Genetics & Genomics
OCT 23, 2018
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...
Written By:
Carmen Leitch
JUN 26, 2018
Cancer
JUN 26, 2018
An introduction to genomics, transcriptomics, proteomics, epigenomics, and metabolomics.
Written By:
Mauri Brueggeman
MAY 21, 2018
Cancer
MAY 21, 2018
Epigenetics is defined and outlined as important in gene expression and a possible cause for cancer development & as a t
...
Written By:
Mauri Brueggeman
MAY 17, 2018
Immunology
MAY 17, 2018
A detailed investigation into the epigenome of rheumatoid arthritis (RA) patients revealed unexpected similarities betwe
...
Written By:
Kara Marker
DEC 17, 2017
Drug Discovery & Development
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