Histone Modification
A histone modification is a covalent post-translational modification (PTM) to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. The PTMs made to histones can impact gene expression by altering chromatin structure or recruiting histone modifiers. Histone proteins act to package DNA, which wraps around the eight histones, into chromosomes. Histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair.
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JAN 22, 2019Genetics & Genomics
JAN 22, 2019Scientists have taken a close look at what happens on the molecular level when DNA is inserted into the genome of a plant....Written By: Carmen LeitchOCT 23, 2018Genetics & Genomics
OCT 23, 2018We are born with a genome that doesn't change, but small modifications can be made to that genetic material throughout our lives....Written By: Carmen LeitchJUN 26, 2018Cancer
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MAY 21, 2018Epigenetics is defined and outlined as important in gene expression and a possible cause for cancer development & as a target for cancer detection. Researchers are looking at new approaches....Written By: Mauri BrueggemanMAY 17, 2018Immunology
MAY 17, 2018A detailed investigation into the epigenome of rheumatoid arthritis (RA) patients revealed unexpected similarities between RA and Huntington’s diseas...Written By: Kara MarkerDEC 17, 2017Drug Discovery
AUG 16, 2017Microbiology
AUG 16, 2017Researchers at the National Institute of Allergy and Infectious Disease knew that some viruses - herpes simplex virus, for example - integrate their own ge...Written By: Kerry EvansJAN 31, 2017Genetics & Genomics
JAN 31, 2017Gene Essential for Reprogramming Human Amniotic Stem Cells...Written By: Jennifer EllisNOV 20, 2016Cell & Molecular Biology
NOV 20, 2016A study published in Cell demonstrated how the brains of patients with different kinds of autism spectrum disorder (ASD) share common epigenetic modificati...Written By: Carmen LeitchSEP 18, 2016Cell & Molecular Biology
SEP 18, 2016Researchers have created a new, fluorescent probe that detects a specific methyl group on histones in living cells. This tool, a mintbody or modification-s...Written By: Carmen LeitchMAY 14, 2015Genetics & Genomics
MAY 14, 2015Understanding the function of certain groups of non-coding RNAs will lead to a greater understanding of how certain illnesses that only occur in humans are...Written By: Ilene SchneiderAPR 22, 2015Genetics & Genomics
APR 22, 2015Could the epigenome provide a new avenue for gene therapies and guiding stem cell differentiation?
...Written By: Robert WoodardAUG 22, 2014Genetics & Genomics
AUG 22, 2014Epigenetics has a large say in blood formation.
Blood stem cells have the potential to turn into any type of blood cell, whether it is the oxyge...Written By: Ilene Schneider
JAN 22, 2019
Genetics & Genomics
JAN 22, 2019
Scientists have taken a close look at what happens on the molecular level when DNA is inserted into the genome of a plant....
Written By:
Carmen Leitch
OCT 23, 2018
Genetics & Genomics
OCT 23, 2018
We are born with a genome that doesn't change, but small modifications can be made to that genetic material throughout our lives....
Written By:
Carmen Leitch
JUN 26, 2018
Cancer
JUN 26, 2018
An introduction to genomics, transcriptomics, proteomics, epigenomics, and metabolomics....
Written By:
Mauri Brueggeman
MAY 21, 2018
Cancer
MAY 21, 2018
Epigenetics is defined and outlined as important in gene expression and a possible cause for cancer development & as a target for cancer detection. Researchers are looking at new approaches....
Written By:
Mauri Brueggeman
MAY 17, 2018
Immunology
MAY 17, 2018
A detailed investigation into the epigenome of rheumatoid arthritis (RA) patients revealed unexpected similarities between RA and Huntington’s diseas...
Written By:
Kara Marker
DEC 17, 2017
Drug Discovery
AUG 16, 2017
Microbiology
AUG 16, 2017
Researchers at the National Institute of Allergy and Infectious Disease knew that some viruses - herpes simplex virus, for example - integrate their own ge...
Written By:
Kerry Evans
JAN 31, 2017
Genetics & Genomics
JAN 31, 2017
Gene Essential for Reprogramming Human Amniotic Stem Cells...
Written By:
Jennifer Ellis
NOV 20, 2016
Cell & Molecular Biology
NOV 20, 2016
A study published in Cell demonstrated how the brains of patients with different kinds of autism spectrum disorder (ASD) share common epigenetic modificati...
Written By:
Carmen Leitch
SEP 18, 2016
Cell & Molecular Biology
SEP 18, 2016
Researchers have created a new, fluorescent probe that detects a specific methyl group on histones in living cells. This tool, a mintbody or modification-s...
Written By:
Carmen Leitch
MAY 14, 2015
Genetics & Genomics
MAY 14, 2015
Understanding the function of certain groups of non-coding RNAs will lead to a greater understanding of how certain illnesses that only occur in humans are...
Written By:
Ilene Schneider
APR 22, 2015
Genetics & Genomics
APR 22, 2015
Could the epigenome provide a new avenue for gene therapies and guiding stem cell differentiation?
...
...
Written By:
Robert Woodard
AUG 22, 2014
Genetics & Genomics
AUG 22, 2014
Epigenetics has a large say in blood formation.
Blood stem cells have the potential to turn into any type of blood cell, whether it is the oxyge...
Blood stem cells have the potential to turn into any type of blood cell, whether it is the oxyge...
Written By:
Ilene Schneider
