Library preparation is the initial part of the procedure for next generation sequencing. During this step, DNA or RNA is fragmented and then adhered, or ligated, to the sequencing platform allowing for sample identification. In ligation-based library prep fragmentation and ligation occur in two separate steps while in tagmentation-based library prep fragmentation and ligation are completed in one step.
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DNA fragmentation is a critical step in preparing DNA libraries for short read-based protocols. The two primary methods are mechanical shearing (using acoustic technology like Covaris) and e...
RNA-Seq remains a critical and robust methodology in understanding cellular and organismal changes associated with development and disease. Advances in automation have helped reduce the cost...
In the era of advanced biotechnology, automation plays a crucial role in accelerating cancer research. Next-generation sequencing (NGS) technology has revolutionized cancer research, but lab...
Advancements in Next Generation Sequencing (NGS) are changing the genomics industry, favoring those with scale. Quest Diagnostics' clinical expertise, combined with our infrastructure, p...
JUL 25, 2023 | 8:00 PM
C.E. CREDITS
NEED ABSTRACT Learning Objectives Understand how the challenges of amplification from low input DNA, including single cells, can be overcome Discover why more researchers are using a next ge...
JUN 27, 2023 | 11:00 AM
C.E. CREDITS
Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths, according to the World Health Organization. Many cancers can be cu...
Date: December 13, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Understanding the diversity of repair outcomes after introducing a genomic cut is essential for realizing the therapeu...
Date: November 16, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Immunopeptides play an essential role in adaptive immunity by activating and ensuring T-cell specificity. Mass spectro...
Date: October 04, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The Miro Canvas is a new platform which enables full walkaway automation of complex next generation sequencing (NGS) s...
Date: July 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology,...
Date: June 09, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Thousands of researchers worldwide have utilized microfluidics technology from Standard BioTools for genomics application...
Wastewater samples are challenging substrates for nucleic acid extraction, and choice of extraction method will determine the success of downstream analysis. Extraction methods must be able...
APR 19, 2022 | 7:30 AM
C.E. CREDITS
While early genetic diagnosis can guide critical care management, the turnaround time for whole genome based diagnostic testing is months. Recent programs in neonatal populations have reduce...
Date: March 02, 2022 Time: 9:00am (PST), 12:00pm (EST) Single cell RNA-seq is known to only capture a small fraction of the transcriptome of each cell. Often, this is due to inherent limitat...
Date: November 15, 2021 Time: 6:00am (PDT), 9:00am (EDT) Targeted sequencing of respiratory viruses’ genomes is important to identify novel viral variants. Compared to amplicon sequenc...
Date: November 8, 2021 Time: 8:00am (PDT), 11:00am (EDT) Explore the adaptability of your KingFisher instrument. Discover all the ways your Thermo Scientific™ KingFisher™ system...
Date: October 27, 2021 Time: 10:00am (PDT), 1:00pm (EDT) The COVID-19 pandemic has brought global awareness to the dangers of emerging pathogens to human health and welfare. Common molecular...
Date: October 13, 2021 Time: 10:00am (PDT), 01:00pm (EDT) Clinically-relevant applications, such as somatic variant detection, continue to push the bounds...
I will discuss the development of the “Midnight” panel for faster, simpler, and less expensive SARS-CoV-2 genome sequencing. We show that using a multiplexed set of primers in co...
Date: August 25, 2021 Time: 7:00am PDT DreamPrep NGS is a complete solution that combines the Fluent® Automation Workstation, the Infinite® F Nano+ plate reader and Tecan Genomics&rsq...
The increase in the number and diversity of drugs of abuse is a major concern; it also presents significant challenges for forensic laboratories who are involved in the analysis of seized su...