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Microsatellite Instability (MSI)
Often caused by mistakes that are left uncorrected when DNA has been copied in a cell, microsatellite instability (MSI) is a condition that occurs in a certain type of cell, such as a cancer cell, where regions of the repeated DNA alter in length, showing instability due to a defect in mismatch repair DNA proteins. Since the errors go uncorrected, they accumulate and through DNA replication, the sequences are not preserved, ultimately creating new microsatellites.
What's Popular in Microsatellite Instability (MSI)
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AUG 29, 2025eBooksDownload your copy of "Enable precision medicine with comprehensive genomic profiling CGP" eBook to learn more ...SEP 19, 2022Genetics & Genomics
The promise of NGS in personalized cancer care For years, next-generation sequencing (NGS) has enabled oncologists to id ...Sponsored By: Roche SequencingAPR 09, 2020Cancer
Results from a study published in Nature Medicine highlights the benefits of receiving pre-surgery immunotherapy for som ...Written By: Kathryn DeMuth SullivanDEC 18, 2019Genetics & Genomics
Cancer cells can adapt to mutations in the genome that might kill the cells by altering the activity of their genes.Written By: Carmen LeitchMAY 26, 2017Cancer
For the first time, the US FDA approved a cancer drug for patients based on presence of genetic biomarkers. Whereas canc ...
AUG 29, 2025
eBooks
Download your copy of "Enable precision medicine with comprehensive genomic profiling CGP" eBook to learn more
...
SEP 19, 2022
Genetics & Genomics
The promise of NGS in personalized cancer care For years, next-generation sequencing (NGS) has enabled oncologists to id
...
Sponsored By:
Roche Sequencing
APR 09, 2020
Cancer
Results from a study published in Nature Medicine highlights the benefits of receiving pre-surgery immunotherapy for som
...
Written By:
Kathryn DeMuth Sullivan
DEC 18, 2019
Genetics & Genomics
Cancer cells can adapt to mutations in the genome that might kill the cells by altering the activity of their genes.
Written By:
Carmen Leitch
MAY 26, 2017
Cancer
For the first time, the US FDA approved a cancer drug for patients based on presence of genetic biomarkers. Whereas canc
...
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NOV 29, 2023 | 9:00 AM
Tumor genomic profiling can be complicated, especially for diseases that commonly have multiple different genomic biomarkers of interest, such as non-small cell lung cancer (NSCLC) and color...MAY 31, 2022 | 9:00 AM
Date: May 31, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Introducing Nanostring’s latest spatial platform, CosMx Spatial Molecular Imager (SMI). Offering high-plex, multiomi...MAY 03, 2022 | 8:00 AM
Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...NOV 05, 2020 | 12:00 AM
Dr. Bacher will be discussing the history and evolution of MSI, the differences between popular testing methods, and what the future holds for this powerful biomarker....
OCT 08, 2020 | 10:00 AM
DATE: October 8, 2020 TIME: 1:00pm PDT Microsatellite instability (MSI) has evolved as a marker of potential hereditary cancer risk and is now a tissue agnostic immune biomarker with a broad...
NOV 29, 2023 | 9:00 AM
Tumor genomic profiling can be complicated, especially for diseases that commonly have multiple different genomic biomarkers of interest, such as non-small cell lung cancer (NSCLC) and color...
MAY 31, 2022 | 9:00 AM
Date: May 31, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Introducing Nanostring’s latest spatial platform, CosMx Spatial Molecular Imager (SMI). Offering high-plex, multiomi...
MAY 03, 2022 | 8:00 AM
Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
NOV 05, 2020 | 12:00 AM
Dr. Bacher will be discussing the history and evolution of MSI, the differences between popular testing methods, and what the future holds for this powerful biomarker....
OCT 08, 2020 | 10:00 AM
DATE: October 8, 2020 TIME: 1:00pm PDT Microsatellite instability (MSI) has evolved as a marker of potential hereditary cancer risk and is now a tissue agnostic immune biomarker with a broad...
JUL 02, 2020 | 12:15 PM
Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
MAY 08, 2020 | 8:00 AM
DATE: May 8, 2020 TIME: 8:00am PT, 11:00am ET Microsatellite instability (MSI) is the condition of genetic hypermutability that results from impaired DNA mismatch repair (MMR). Studies indic...
OCT 10, 2019 | 12:00 PM
Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
Speaker:
Ravindra Kolhe, MD, PhD
JUN 20, 2019 | 10:30 AM
Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
Speaker:
Beate Litzenburger, Ph.D.
, Raed Samara, PhD
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C.E. CREDITS
DXRX LabTalks are a dynamic webinar series led by the foremost experts within the DXRX Lab Network. These sessions are designed to connect you with cutting-edge knowledge and provide invalua...MAR 20, 2024 | 8:30 PM PDT
The premier event in NGS education is now available on demand. Since 2020, OncomineWorld meetings have brought together thousands of scientists and professionals from around the world each y...MAR 30, 2023 | 12:00 AM PDT
Don’t miss the premier event in NGS education. Since 2020, OncomineWorld meetings have brought together thousands of scientists and professionals from around the world each year to adv...
Each year, the OncomineWorld virtual NGS education meeting brings together thousands of scientists and professionals who are dedicated to the advancement...Session 3: October 26, 2021 9:00 AM CDT
Thought this MSI Series might be of interest to you! Session 2 is on June 29th and you view Session 1 via On Demand. Enjoy!...
C.E. CREDITS
DXRX LabTalks are a dynamic webinar series led by the foremost experts within the DXRX Lab Network. These sessions are designed to connect you with cutting-edge knowledge and provide invalua...
MAR 20, 2024
| 8:30 PM PDT
The premier event in NGS education is now available on demand. Since 2020, OncomineWorld meetings have brought together thousands of scientists and professionals from around the world each y...
MAR 30, 2023
| 12:00 AM PDT
Don’t miss the premier event in NGS education. Since 2020, OncomineWorld meetings have brought together thousands of scientists and professionals from around the world each year to adv...
Each year, the OncomineWorld virtual NGS education meeting brings together thousands of scientists and professionals who are dedicated to the advancement...
Session 3: October 26, 2021 9:00 AM CDT
Thought this MSI Series might be of interest to you! Session 2 is on June 29th and you view Session 1 via On Demand. Enjoy!...
SEP 29, 2020
| 6:00 AM PDT
Due to the fact that many large events and scientific conferences have been cancelled, we want to provide you with an outlet to present your research and learn from others in our community....
JUN 30, 2020
| 7:00 PM PDT
APJ Virtual Genetic Solutions Tour 2020 by Thermo Fisher Scientific | July 1st - 2nd, 2020. Join us to move your genomics research forward faster. Register now...
OCT 09, 2019
| 6:00 AM PDT
Labroots and the Cancer Research and Oncology Planning Committee are pleased to announce the 7th Annual Event in the Cancer Research & Oncology Week Virtual Event Series!...
JUN 20, 2019
| 6:00 AM PDT
Our 4th Annual Event in the Precision Medicine Virtual Event Series is now available On-Demand!...