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    Spatial Genomics

    Spatial genomics utilizes a variety of methods in order to measure the gene activity within a tissue sample, subsequently allowing for the mapping of where the gene activity is occurring.

    Webinars

    • SEP 23, 2020 | 10:30 AM
      New Insights Gained with Imaging Mass Cytometry
      New Insights Gained with Imaging Mass Cytometry
      Speaker TBD 10:30–10:50 am PDT Exploring the immune tumor microenvironment of hepatocellular carcinoma with Imaging Mass Cytometry™ 10:50 am–11:10 am PDT Presented By: Won...
      Speaker: Won Jin Ho, MD , Melissa B. Davis, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 12:00 AM
      Deep learning to integrate histology with spatial transcriptomics
      Deep learning to integrate histology with spatial transcriptomics
      I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
      Speaker: James Zou
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
      GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
      Speaker: Kit Fuhrman
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 17, 2020 | 11:00 AM
      Host and Viral Transcriptomes During COVID-19 Infection
      Host and Viral Transcriptomes During COVID-19 Infection
      In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
      Speaker: Christopher E. Mason, PhD
      Presented at: Coronavirus Series
      3
      SEP 02, 2020 | 7:00 AM
      Whole transcriptome in situ cell atlas reveals cellular composition and interactions in the developing human brain
      Whole transcriptome in situ cell atlas reveals cellular composition...
      DATE: September 2, 2020 TIME: 03:00pm PDT, 6:00pm EDT Spatial omics is an expanding collection of methods to examine biological molecules in their geographical context. By retaining the prec...
      Speaker: Dr. Omer Bayraktar , Pawel Zajac, Ph.D. , Dr. Rudy Van Eijsden
      Sponsored By: Illumina, NanoString Technologies
      19 3
      JUN 17, 2020 | 1:30 PM
      Insights into the Pathogenesis of COVID-19 as Revealed by Spatial Biology
      Insights into the Pathogenesis of COVID-19 as Revealed by Spatial...
      Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
      Speaker: Joseph M. Beechem, PhD , Christopher E. Mason, PhD , Robert Schwartz, PhD
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      9
      JUN 02, 2020 | 4:30 PM
      Plenary Address
      Plenary Address
      ...
      Speaker: Plenary Keynote: Xiaowei Zhuang, PhD
      Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
      1
      MAY 20, 2020 | 11:15 AM
      Spatial Landscape of the Immune Microenvironment in Metastatic Prostate Cancer using GeoMxâ„¢ Digital Spatial Profiler
      Spatial Landscape of the Immune Microenvironment in Metastatic...
      Metastatic prostate cancer (mPC) is a phenotypically diverse disease with poor responses to immune based therapeutics. Development of immunotherapeutic strategies for mPC is hampered by the...
      Speaker: Peter Nelson, MD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 1:45 PM
      Cancer Transcriptome Atlas with NGS Readout - The essential tool for spatial genomics in oncology
      Cancer Transcriptome Atlas with NGS Readout - The essential tool...
      While many technologies focus on either exploring the spatial context of a handful of targets, or expression patterns of hundreds or thousands of targets in bulk samples or dissociated singl...
      Speaker: Kit Fuhrman, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 1:15 PM
      Immune Infiltration Influences the Survival of Pancreatic Cancer Patients
      Immune Infiltration Influences the Survival of Pancreatic Cancer...
      Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
      Speaker: Dana Mustafa, Ph.D.
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 11:45 AM
      Single-nucleus and Spatial Transcriptomics of Archival Pancreatic Ductal Adenocarcinoma after Neoadjuvant Treatment
      Single-nucleus and Spatial Transcriptomics of Archival Pancreatic...
      Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory disease and existing molecular subtypes do not inform clinical decisions. Previously-identified bulk transcriptomic sub...
      Speaker: William L. Hwang, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 11:15 AM
      Digital Spatial Mapping of the Immune Landscape of Triple Negative Breast Cancer Reveals Novel Features of Immune-tumor Cell Interaction
      Digital Spatial Mapping of the Immune Landscape of Triple Negative...
      Background: Growing evidence supports the critical role of preexisting immune response in triple negative breast cancer (TNBC). However, there are limitations with current evaluation approac...
      Speaker: E. Aubrey Thompson, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      APR 21, 2020 | 1:30 PM
      Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
      Spatially Resolved Molecular Investigation of Triple Negative...
      Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
      Speaker: Dina Finan, PhD , Stephen Williams, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 12:00 AM
      Single Cell Multi-omics: Solving the Jigsaw
      Single Cell Multi-omics: Solving the Jigsaw
      Since the introduction of single cell sequencing techniques to the genomics community, interest in its use has grown exponentially and the number of single cell publications has exploded. Th...
      Speaker: Ivan Lukić, MD, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 16, 2020 | 9:00 AM
      Visualize more biomarkers and extract more insights: Moving from single marker IHC to multiplex IF
      Visualize more biomarkers and extract more insights: Moving from...
      DATE: April 16, 2020 TIME: 9:00am PT, 12:00pm ET There is an increasing need to evaluate and understand unique phenotypes and mechanisms of action within the tumor microenvironment. Existing...
      Speaker: Scott Lawrence (M.S., HT(ASCP)) [C] , Katir Patel, PhD
      Sponsored By: Ultivue
      5
      APR 15, 2020 | 9:00 AM
      Single-cell multi-omics: DNA methylation and 3D genome
      Single-cell multi-omics: DNA methylation and 3D genome
      DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
      Speaker: Yaping Liu, Ph.D.
      Sponsored By: Zymo Research
      9 3
      SEP 26, 2019 | 1:30 PM
      The Visium Spatial Gene Expression Solution: Gene Expression with Spatial Context
      The Visium Spatial Gene Expression Solution: Gene Expression with...
      RNA-Seq has been used for the past decade to gain significant insights into gene expression. Using bulk methods however only allow for an understanding of the average gene expression within a...
      Speaker: Zachary Bent
      Presented at: Cell Biology Virtual Event Series 2019
      1
      SEP 26, 2019 | 10:30 AM
      Discover the genes that matter while preserving spatial information: The Visium Gene Expression Solution
      Discover the genes that matter while preserving spatial information:...
      The ability to discern spatial gene expression differences in complex biological systems is critical to our understanding of developmental biology and the progression of disease. However, the...
      Speaker: Nikhil Rao
      Presented at: Cell Biology Virtual Event Series 2019
      1
      SEP 26, 2019 | 9:00 AM
      Identification of Novel Biomarker Candidates for Early Detection of Melanoma
      Identification of Novel Biomarker Candidates for Early Detection...
      Early detection is critical for improved survival in melanoma. Melanocytic nevi are extremely common benign tumors that mimic melanoma and are therefore commonly biopsied. Currently, the dete...
      Speaker: Margaret Hoang, PhD , Maija Kiuru, PhD
      Presented at: Cell Biology Virtual Event Series 2019
      1
      SEP 17, 2019 | 9:00 AM
      Spatial transcriptomics reveals insights into the melanoma tumour microenvironment
      Spatial transcriptomics reveals insights into the melanoma tumour...
      DATE: September 17, 2019TIME: 9:00am PTSpatial Transcriptomics (ST) technology reveals gene expression from up to one thousand spots across a tissue section. In this webinar, Dr. H...
      Speaker: Hanna Eriksson, M.D., PhD , Kim Thrane , Dr. Aida Soler , Dr. Stephen Hague
      Illumina , 10x Genomics
      2
      AUG 27, 2019 | 9:00 AM
      Akoya Biosciences Webinar Series:  Comprehensive Meta-analysis of Biomarker Technologies for Predictive Response of PD-1/PD-L1 Checkpoint Therapies
      Akoya Biosciences Webinar Series: Comprehensive Meta-analysis...
      DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
      Speaker: Cliff Hoyt, PhD , Steve Lu
      Sponsored By: Akoya Biosciences
      5
      JUN 20, 2019 | 1:30 PM
      Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
      Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
      Tumor heterogeneity is a hallmark of cancer and can have significant impact on identifying drivers, including those that may be therapeutically relevant. Although, the traditional sequencing...
      Speaker: Lee Gibbs, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 20, 2019 | 6:00 AM
      Connecting Genetic and Transcriptional Variation in Acute Myeloid Leukemia at Single-Cell Resolution
      Connecting Genetic and Transcriptional Variation in Acute Myeloid...
      Virtually all tumors are genetically heterogeneous, containing subclonal populations of cells that are defined by distinct mutations. Subclones can have unique phenotypes that influence disea...
      Speaker: Stephen Williams, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      2
      MAR 21, 2019 | 7:00 AM
      Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
      Phenotyping the tumor micro-environment with advanced tissue-based...
      DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
      Speaker: Katir Patel, PhD
      Sponsored By: Ultivue
      11
    SEP 23, 2020 | 10:30 AM
    New Insights Gained with Imaging Mass Cytometry
    New Insights Gained with Imaging Mass Cytometry
    Speaker TBD 10:30–10:50 am PDT Exploring the immune tumor microenvironment of hepatocellular carcinoma with Imaging Mass Cytometry™ 10:50 am–11:10 am PDT Presented By: Won...
    Speaker: Won Jin Ho, MD , Melissa B. Davis, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 12:00 AM
    Deep learning to integrate histology with spatial transcriptomics
    Deep learning to integrate histology with spatial transcriptomics
    I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
    Speaker: James Zou
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 23, 2020 | 12:00 AM
    GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
    GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
    GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
    Speaker: Kit Fuhrman
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 17, 2020 | 11:00 AM
    Host and Viral Transcriptomes During COVID-19 Infection
    Host and Viral Transcriptomes During COVID-19 Infection
    In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
    Speaker: Christopher E. Mason, PhD
    Presented at: Coronavirus Series
    3
    SEP 02, 2020 | 7:00 AM
    Whole transcriptome in situ cell atlas reveals cellular composition and interactions in the developing human brain
    Whole transcriptome in situ cell atlas reveals cellular composition...
    DATE: September 2, 2020 TIME: 03:00pm PDT, 6:00pm EDT Spatial omics is an expanding collection of methods to examine biological molecules in their geographical context. By retaining the prec...
    Speaker: Dr. Omer Bayraktar , Pawel Zajac, Ph.D. , Dr. Rudy Van Eijsden
    Sponsored By: Illumina, NanoString Technologies
    19 3
     
     
  • JUN 17, 2020 | 1:30 PM
    Insights into the Pathogenesis of COVID-19 as Revealed by Spatial Biology
    Insights into the Pathogenesis of COVID-19 as Revealed by Spatial...
    Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
    Speaker: Joseph M. Beechem, PhD , Christopher E. Mason, PhD , Robert Schwartz, PhD
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    9
    JUN 02, 2020 | 4:30 PM
    Plenary Address
    Plenary Address
    ...
    Speaker: Plenary Keynote: Xiaowei Zhuang, PhD
    Presented at: 2020 6th annual BRAIN Initiative Investigators Virtual Meeting
    1
    MAY 20, 2020 | 11:15 AM
    Spatial Landscape of the Immune Microenvironment in Metastatic Prostate Cancer using GeoMxâ„¢ Digital Spatial Profiler
    Spatial Landscape of the Immune Microenvironment in Metastatic...
    Metastatic prostate cancer (mPC) is a phenotypically diverse disease with poor responses to immune based therapeutics. Development of immunotherapeutic strategies for mPC is hampered by the...
    Speaker: Peter Nelson, MD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 19, 2020 | 1:45 PM
    Cancer Transcriptome Atlas with NGS Readout - The essential tool for spatial genomics in oncology
    Cancer Transcriptome Atlas with NGS Readout - The essential tool...
    While many technologies focus on either exploring the spatial context of a handful of targets, or expression patterns of hundreds or thousands of targets in bulk samples or dissociated singl...
    Speaker: Kit Fuhrman, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 19, 2020 | 1:15 PM
    Immune Infiltration Influences the Survival of Pancreatic Cancer Patients
    Immune Infiltration Influences the Survival of Pancreatic Cancer...
    Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
    Speaker: Dana Mustafa, Ph.D.
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
     
     
  • MAY 19, 2020 | 11:45 AM
    Single-nucleus and Spatial Transcriptomics of Archival Pancreatic Ductal Adenocarcinoma after Neoadjuvant Treatment
    Single-nucleus and Spatial Transcriptomics of Archival Pancreatic...
    Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory disease and existing molecular subtypes do not inform clinical decisions. Previously-identified bulk transcriptomic sub...
    Speaker: William L. Hwang, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 19, 2020 | 11:15 AM
    Digital Spatial Mapping of the Immune Landscape of Triple Negative Breast Cancer Reveals Novel Features of Immune-tumor Cell Interaction
    Digital Spatial Mapping of the Immune Landscape of Triple Negative...
    Background: Growing evidence supports the critical role of preexisting immune response in triple negative breast cancer (TNBC). However, there are limitations with current evaluation approac...
    Speaker: E. Aubrey Thompson, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    APR 21, 2020 | 1:30 PM
    Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
    Spatially Resolved Molecular Investigation of Triple Negative...
    Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
    Speaker: Dina Finan, PhD , Stephen Williams, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 21, 2020 | 12:00 AM
    Single Cell Multi-omics: Solving the Jigsaw
    Single Cell Multi-omics: Solving the Jigsaw
    Since the introduction of single cell sequencing techniques to the genomics community, interest in its use has grown exponentially and the number of single cell publications has exploded. Th...
    Speaker: Ivan Lukić, MD, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 16, 2020 | 9:00 AM
    Visualize more biomarkers and extract more insights: Moving from single marker IHC to multiplex IF
    Visualize more biomarkers and extract more insights: Moving from...
    DATE: April 16, 2020 TIME: 9:00am PT, 12:00pm ET There is an increasing need to evaluate and understand unique phenotypes and mechanisms of action within the tumor microenvironment. Existing...
    Speaker: Scott Lawrence (M.S., HT(ASCP)) [C] , Katir Patel, PhD
    Sponsored By: Ultivue
    5
     
     
  • APR 15, 2020 | 9:00 AM
    Single-cell multi-omics: DNA methylation and 3D genome
    Single-cell multi-omics: DNA methylation and 3D genome
    DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
    Speaker: Yaping Liu, Ph.D.
    Sponsored By: Zymo Research
    9 3
    SEP 26, 2019 | 1:30 PM
    The Visium Spatial Gene Expression Solution: Gene Expression with Spatial Context
    The Visium Spatial Gene Expression Solution: Gene Expression with...
    RNA-Seq has been used for the past decade to gain significant insights into gene expression. Using bulk methods however only allow for an understanding of the average gene expression within a...
    Speaker: Zachary Bent
    Presented at: Cell Biology Virtual Event Series 2019
    1
    SEP 26, 2019 | 10:30 AM
    Discover the genes that matter while preserving spatial information: The Visium Gene Expression Solution
    Discover the genes that matter while preserving spatial information:...
    The ability to discern spatial gene expression differences in complex biological systems is critical to our understanding of developmental biology and the progression of disease. However, the...
    Speaker: Nikhil Rao
    Presented at: Cell Biology Virtual Event Series 2019
    1
    SEP 26, 2019 | 9:00 AM
    Identification of Novel Biomarker Candidates for Early Detection of Melanoma
    Identification of Novel Biomarker Candidates for Early Detection...
    Early detection is critical for improved survival in melanoma. Melanocytic nevi are extremely common benign tumors that mimic melanoma and are therefore commonly biopsied. Currently, the dete...
    Speaker: Margaret Hoang, PhD , Maija Kiuru, PhD
    Presented at: Cell Biology Virtual Event Series 2019
    1
    SEP 17, 2019 | 9:00 AM
    Spatial transcriptomics reveals insights into the melanoma tumour microenvironment
    Spatial transcriptomics reveals insights into the melanoma tumour...
    DATE: September 17, 2019TIME: 9:00am PTSpatial Transcriptomics (ST) technology reveals gene expression from up to one thousand spots across a tissue section. In this webinar, Dr. H...
    Speaker: Hanna Eriksson, M.D., PhD , Kim Thrane , Dr. Aida Soler , Dr. Stephen Hague
    Illumina , 10x Genomics
    2
     
     
  • AUG 27, 2019 | 9:00 AM
    Akoya Biosciences Webinar Series:  Comprehensive Meta-analysis of Biomarker Technologies for Predictive Response of PD-1/PD-L1 Checkpoint Therapies
    Akoya Biosciences Webinar Series: Comprehensive Meta-analysis...
    DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
    Speaker: Cliff Hoyt, PhD , Steve Lu
    Sponsored By: Akoya Biosciences
    5
    JUN 20, 2019 | 1:30 PM
    Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
    Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
    Tumor heterogeneity is a hallmark of cancer and can have significant impact on identifying drivers, including those that may be therapeutically relevant. Although, the traditional sequencing...
    Speaker: Lee Gibbs, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 20, 2019 | 6:00 AM
    Connecting Genetic and Transcriptional Variation in Acute Myeloid Leukemia at Single-Cell Resolution
    Connecting Genetic and Transcriptional Variation in Acute Myeloid...
    Virtually all tumors are genetically heterogeneous, containing subclonal populations of cells that are defined by distinct mutations. Subclones can have unique phenotypes that influence disea...
    Speaker: Stephen Williams, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    2
    MAR 21, 2019 | 7:00 AM
    Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
    Phenotyping the tumor micro-environment with advanced tissue-based...
    DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
    Speaker: Katir Patel, PhD
    Sponsored By: Ultivue
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