Surgeries broadly describe procedures used to investigate or treat a medical condition, such as a disease, injury, or bodily impediment. In general, surgeries aim to improve function or appearance or repair a damaged or infected area of the body. Examples of surgeries include angioplasty, joint replacements, cesarean section, organ transplantation, hysterectomy.
A fundamental challenge in developing brain machine interfaces (BMIs) is building a decoder between patterns of brain activity and movement in patients with spinal cord injury, ALS, and amput...
Working memory ability matures late in life, in adolescence or early adulthood, and may be enhanced even in adulthood through cognitive training. The mechanisms through which working memory i...
Miniaturized microscopes in combination with genetically encoded calcium indicators now allow recordings of activity from hundreds of neurons simultaneously in freely moving animals. We are b...
Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder exhibiting both motor and behavioral impairment. Like most neuropsychiatric disorders, its pathophysiology has yet to be...
Dr. Kasthuri is a Neuroscience Researcher at Argonne National Labs and an Assistant Professor (adjunct) in the Dept. of Neurobiology, University of Chicago. He has an MD from Washington...
Basal forebrain cholinergic inputs to the cortex are known to contribute to attentional performance. A major focus of my laboratory has been to study the receptors mediating the effects of ac...
The idea of schizophrenia typically conjures up images of people who hear voices, see visions and have delusional beliefs. However, clinicians have long recognized cognitive dysfunction as on...
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
Sensorimotor integration is important for the acquisition and performance of motor skills. Here,we show the emergence of neuroplastic changes in the interactions between the motor andsomatose...
We are nearing three decades of research on the neural circuits of Pavlovian fear conditioning. The advent of new techniques such as genetic and optogenetic manipulations have greatly advance...
DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETThe last few years have led to great progress in Chile in terms of laboratory animal care and use. There are new legal mandates to prote...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETIn-vivo surgical models are becoming more prevalent and more critical to the drug development process. As the vast majority of ind...
DATE: February 8, 2017TIME: 7:30am PT, 10:30am ETMany of us who believe in the importance of aseptic rodent surgery have lived through the frustration of trying to implement rodent asep...
DATE: December 7, 2016TIME: 8:00am PT, 11:00am ET1,25-dihydroxyvitamin D (1,25[OH]2D) is the active, hormonal form of vitamin D. It is produced from its precursor (vitamin D) by two hyd...
DATE: December 1, 2016TIME: 8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
Over the past 6 years, a number of agents, all mechanistically different, have been approved with a statistically significant survival benefit as monotherapy for treatment of metastatic castr...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Cataract, or vision loss due to clouding of the eye’s lens, is a large and costly international problem. Over 80 million people currently have low vision due to cataract. Cataracts can ...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
A fundamental challenge in developing brain machine interfaces (BMIs) is building a decoder between patterns of brain activity and movement in patients with spinal cord injury, ALS, and amput...
Working memory ability matures late in life, in adolescence or early adulthood, and may be enhanced even in adulthood through cognitive training. The mechanisms through which working memory i...
Miniaturized microscopes in combination with genetically encoded calcium indicators now allow recordings of activity from hundreds of neurons simultaneously in freely moving animals. We are b...
Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder exhibiting both motor and behavioral impairment. Like most neuropsychiatric disorders, its pathophysiology has yet to be...
Dr. Kasthuri is a Neuroscience Researcher at Argonne National Labs and an Assistant Professor (adjunct) in the Dept. of Neurobiology, University of Chicago. He has an MD from Washington...
Basal forebrain cholinergic inputs to the cortex are known to contribute to attentional performance. A major focus of my laboratory has been to study the receptors mediating the effects of ac...
The idea of schizophrenia typically conjures up images of people who hear voices, see visions and have delusional beliefs. However, clinicians have long recognized cognitive dysfunction as on...
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
Sensorimotor integration is important for the acquisition and performance of motor skills. Here,we show the emergence of neuroplastic changes in the interactions between the motor andsomatose...
We are nearing three decades of research on the neural circuits of Pavlovian fear conditioning. The advent of new techniques such as genetic and optogenetic manipulations have greatly advance...
DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETThe last few years have led to great progress in Chile in terms of laboratory animal care and use. There are new legal mandates to prote...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETIn-vivo surgical models are becoming more prevalent and more critical to the drug development process. As the vast majority of ind...
DATE: February 8, 2017TIME: 7:30am PT, 10:30am ETMany of us who believe in the importance of aseptic rodent surgery have lived through the frustration of trying to implement rodent asep...
DATE: December 7, 2016TIME: 8:00am PT, 11:00am ET1,25-dihydroxyvitamin D (1,25[OH]2D) is the active, hormonal form of vitamin D. It is produced from its precursor (vitamin D) by two hyd...
DATE: December 1, 2016TIME: 8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
Over the past 6 years, a number of agents, all mechanistically different, have been approved with a statistically significant survival benefit as monotherapy for treatment of metastatic castr...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Cataract, or vision loss due to clouding of the eye’s lens, is a large and costly international problem. Over 80 million people currently have low vision due to cataract. Cataracts can ...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
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