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    Transcriptome

    The transcriptome is the complete set of all RNA molecules in a cell, a population of cells or in an organism. Researchers can determine when and where each gene is turned on or off in the cells and tissues of an organism after analyzing the entire collection of RNA sequences in a cell.

    Webinars

    • APR 20, 2021 | 12:00 AM
      Cell type-specific vulnerability to traumatic brain injury
      Cell type-specific vulnerability to traumatic brain injury
      Traumatic brain injury (TBI) is best characterized as brain dysfunction caused by an outside force, usually a violent blow to the head, often occurring as a result of a severe sports injury...
      Speaker: Araks Martirosyan, Ph.D.
      Presented at: Genetics Week Virtual Event Series 2021
      1
      APR 20, 2021 | 12:00 AM
      Studying Promoter and Isoform Diversity with Long-Read Transcriptome Sequencing
      Studying Promoter and Isoform Diversity with Long-Read Transcriptome...
      Learning Objectives: 1. Learn about alternative promoters and their role in cancer 2. Learn how long read RNA-Seq helps to study the transcriptome...
      Speaker: Jonathan Göke
      Presented at: Genetics Week Virtual Event Series 2021
      1
      APR 20, 2021 | 12:00 AM
      Integrative Analysis of Single-Cell Combinatorial Long-Read RNA-seq and Single-Cell ATAC-seq in Myogenesis
      Integrative Analysis of Single-Cell Combinatorial Long-Read RNA-seq...
      Learning Objectives: 1. Demonstrate the utility of long-read RNA-sequencing in studying alternative isoforms 2. Define the long-Split-seq approach to profiling the transcriptomes of single-c...
      Speaker: Fairlie Reese, PhD Student
      Presented at: Genetics Week Virtual Event Series 2021
      1
      APR 20, 2021 | 12:00 AM
      Practical Considerations and Best Practices for Single Cell and Spatial Transcriptomics
      Practical Considerations and Best Practices for Single Cell and...
      Learning Obejctives: 1. Understand the key requirements for sample preparation in a single cell and/or spatial transcriptomics experiment 2. Learn the synergies between a combined single cel...
      Speaker: Neil Winegarden, MSc
      Presented at: Genetics Week Virtual Event Series 2021
      1
      APR 20, 2021 | 12:00 AM
      Illuminating Biology with Spatially Resolved, Single-cell Transcriptomics
      Illuminating Biology with Spatially Resolved, Single-cell Transcriptomics
      Biological systems are comprised of numerous cell types, intricately organized to form functional tissues and organs. Cell atlas initiatives with single-cell RNA sequencing have begun to cha...
      Speaker: Jiang He
      Presented at: Genetics Week Virtual Event Series 2021
      1
      APR 14, 2021 | 6:00 AM
      A two-pronged approach to tackle COVID-19: Lessons learned from temporal and spatial expression analysis of infected tissue
      A two-pronged approach to tackle COVID-19: Lessons learned from...
      Two studies on the immunology of COVID-19 are included in this webinar: First, Eugenia Ong, PhD with the Viral Research and Experimental Medicine Centre @ SingHealth Duke-NUS (ViREMiCS) and...
      Speaker: Eugenia Z. Ong, PhD , Joe Poh Sheng Yeong, MBBS PhD Mmed (Path)
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      2
      MAR 24, 2021 | 12:00 AM
      Terpenes: Understanding the Genetics Behind Taste and Smell
      Terpenes: Understanding the Genetics Behind Taste and Smell
      Terpenes are a broad class of chemicals that are found throughout the Cannabis plant that produce the unique aroma and taste of your favorite variety. Cannabis breeders have been selecting f...
      Speaker: Christopher Pauli
      Presented at: Cannabis Sciences Virtual Event Series 2021
      3
      MAR 18, 2021 | 8:00 AM
      Facilitating transcriptomics of sensitive target cells with gentle cell sorting
      Facilitating transcriptomics of sensitive target cells with gentle...
      DATE: March 18, 2021 TIME: 8:00am PDT Sequencing of bulk cells, single cells, and nuclei is opening doors in the understanding of complex biological processes....
      Speaker: Alexander Jonsson , Dr. Alina Steinbach
      Sponsored By: Miltenyi Biotec
      11
      FEB 24, 2021 | 12:00 PM
      Deep Mechanistic profiling of immune oncology drug combinations in cancer patients with CIVO intratumoral micro-dosing and NanoString's GeoMx® Digital Spatial Profiler
      Deep Mechanistic profiling of immune oncology drug combinations...
      With an introduction by Sarah Warren, the Senior Director of Translational Science, this webinar will open by providing a brief technology overview of NanoString Technologies. Dr. Warren wil...
      Speaker: Jason Frazier , Sarah Warren, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      Sponsored By: NanoString Technologies
      2
      DEC 03, 2020 | 10:30 AM
      The Immunology of COVID-19: A dynamic immune signature for prognosis and spatial transcriptomics of lung tissue
      The Immunology of COVID-19: A dynamic immune signature for prognosis...
      The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has spread globally, causing a pandemic of respiratory illness designated coronavirus disease 20...
      Speaker: Arutha Kulasinghe, PhD , Miguel Muñoz-Ruiz, PhD
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      3
      NOV 19, 2020 | 9:00 AM
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
      Speaker: Kok Hao Chen , Alan Mullan, PhD
      Sponsored By: Andor
      6 2
      NOV 16, 2020 | 8:00 AM
      Targeted single-cell RNA sequencing enables genome-scale CRISPR screens
      Targeted single-cell RNA sequencing enables genome-scale CRISPR...
      Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
      Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer
      Sponsored By: Illumina
      11
      November 13, 2020 6:00 PM PST | November 14, 2020 10:00 AM SGT
      Q&A Session (In the RoundTable Room)
      Q&A Session (In the RoundTable Room)
      Visit the RoundTable Room to participate in live Q&A with all the speakers!...
      Speaker: Charalambos C. Solomides, MD , Sara Eglitis, MS, QIHC , Faruk Erdem Kombak, MD , Srabani Bhaumik, PhD , Nelson Alexander, PhD
      Presented at: DISCOVERY Global User Symposium
      0
      November 13, 2020 5:00 PM PST | November 14, 2020 9:00 AM SGT
      Representative sampling to address tumor heterogeneity
      Representative sampling to address tumor heterogeneity
      Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
      Speaker: Nelson Alexander, PhD
      Presented at: DISCOVERY Global User Symposium
      2
      November 12, 2020 11:00 AM PST | 6:00 PM GMT
      Q&A Session (In the RoundTable Room)
      Q&A Session (In the RoundTable Room)
      Visit the RoundTable Room to participate in live Q&A with all the speakers!...
      Speaker: Charalambos C. Solomides, MD , Sara Eglitis, MS, QIHC , Faruk Erdem Kombak, MD , Srabani Bhaumik, PhD , Nelson Alexander, PhD
      Presented at: DISCOVERY Global User Symposium
      1
      November 12, 2020 10:00 AM PST | 5:00 PM GMT
      Representative sampling to address tumor heterogeneity
      Representative sampling to address tumor heterogeneity
      Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
      Speaker: Nelson Alexander, PhD
      Presented at: DISCOVERY Global User Symposium
      2
      NOV 09, 2020 | 10:00 AM
      TARGETED PROFILING OF CRITICALLY ILL SARS-CoV-2 SUBJECTS: FROM TRANSCRIPTOME TO PROTEOME
      TARGETED PROFILING OF CRITICALLY ILL SARS-CoV-2 SUBJECTS: FROM...
      Date: November 9th, 2020 Time: 10:00am PDT SARS-CoV-2 continues to spread rapidly with critically ill patients admitted to the intensive care unit (ICU), where the mortality rate is reported...
      Speaker: Douglas Fraser
      Sponsored By: Thermo Fisher Scientific
      16 2
      OCT 29, 2020 | 6:00 AM
      Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
      Single-cell sequencing to investigate epigenetic mechanisms in...
      Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
      Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
      Sponsored By: Illumina, Dolomite Bio
      15
      OCT 08, 2020 | 12:00 AM
      Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
      Transcriptome analysis of breast cancer clinical specimens with...
      Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
      Speaker: Masahito Kawazu, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
      Elucidation of remdesivir cytotoxicity pathways through genome-wide...
      The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
      Speaker: Minja Velimirovic, MSc, PhD Candidate
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      Transcriptomic signature : a spatially resolved analysis of the nephron structures in chronic kidney disease
      Transcriptomic signature : a spatially resolved analysis of the...
      Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for...
      Speaker: Paolo Cravedi, MD, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      2
      SEP 23, 2020 | 12:00 AM
      Deep learning to integrate histology with spatial transcriptomics
      Deep learning to integrate histology with spatial transcriptomics
      I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
      Speaker: James Zou
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
      GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
      Speaker: Kit Fuhrman
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      Extracellular Matrix in Renal Development and Cancer
      Extracellular Matrix in Renal Development and Cancer
      The extracellular matrix (ECM) is a three-dimensional structure that provides physical support for tissues/organs and biochemical/biomechanical cues for tissue morphogenesis, differentiation...
      Speaker: Astgik Petrosyan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      4
    APR 20, 2021 | 12:00 AM
    Cell type-specific vulnerability to traumatic brain injury
    Cell type-specific vulnerability to traumatic brain injury
    Traumatic brain injury (TBI) is best characterized as brain dysfunction caused by an outside force, usually a violent blow to the head, often occurring as a result of a severe sports injury...
    Speaker: Araks Martirosyan, Ph.D.
    Presented at: Genetics Week Virtual Event Series 2021
    1
    APR 20, 2021 | 12:00 AM
    Studying Promoter and Isoform Diversity with Long-Read Transcriptome Sequencing
    Studying Promoter and Isoform Diversity with Long-Read Transcriptome...
    Learning Objectives: 1. Learn about alternative promoters and their role in cancer 2. Learn how long read RNA-Seq helps to study the transcriptome...
    Speaker: Jonathan Göke
    Presented at: Genetics Week Virtual Event Series 2021
    1
    APR 20, 2021 | 12:00 AM
    Integrative Analysis of Single-Cell Combinatorial Long-Read RNA-seq and Single-Cell ATAC-seq in Myogenesis
    Integrative Analysis of Single-Cell Combinatorial Long-Read RNA-seq...
    Learning Objectives: 1. Demonstrate the utility of long-read RNA-sequencing in studying alternative isoforms 2. Define the long-Split-seq approach to profiling the transcriptomes of single-c...
    Speaker: Fairlie Reese, PhD Student
    Presented at: Genetics Week Virtual Event Series 2021
    1
    APR 20, 2021 | 12:00 AM
    Practical Considerations and Best Practices for Single Cell and Spatial Transcriptomics
    Practical Considerations and Best Practices for Single Cell and...
    Learning Obejctives: 1. Understand the key requirements for sample preparation in a single cell and/or spatial transcriptomics experiment 2. Learn the synergies between a combined single cel...
    Speaker: Neil Winegarden, MSc
    Presented at: Genetics Week Virtual Event Series 2021
    1
    APR 20, 2021 | 12:00 AM
    Illuminating Biology with Spatially Resolved, Single-cell Transcriptomics
    Illuminating Biology with Spatially Resolved, Single-cell Transcriptomics
    Biological systems are comprised of numerous cell types, intricately organized to form functional tissues and organs. Cell atlas initiatives with single-cell RNA sequencing have begun to cha...
    Speaker: Jiang He
    Presented at: Genetics Week Virtual Event Series 2021
    1
     
     
  • APR 14, 2021 | 6:00 AM
    A two-pronged approach to tackle COVID-19: Lessons learned from temporal and spatial expression analysis of infected tissue
    A two-pronged approach to tackle COVID-19: Lessons learned from...
    Two studies on the immunology of COVID-19 are included in this webinar: First, Eugenia Ong, PhD with the Viral Research and Experimental Medicine Centre @ SingHealth Duke-NUS (ViREMiCS) and...
    Speaker: Eugenia Z. Ong, PhD , Joe Poh Sheng Yeong, MBBS PhD Mmed (Path)
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    2
    MAR 24, 2021 | 12:00 AM
    Terpenes: Understanding the Genetics Behind Taste and Smell
    Terpenes: Understanding the Genetics Behind Taste and Smell
    Terpenes are a broad class of chemicals that are found throughout the Cannabis plant that produce the unique aroma and taste of your favorite variety. Cannabis breeders have been selecting f...
    Speaker: Christopher Pauli
    Presented at: Cannabis Sciences Virtual Event Series 2021
    3
    MAR 18, 2021 | 8:00 AM
    Facilitating transcriptomics of sensitive target cells with gentle cell sorting
    Facilitating transcriptomics of sensitive target cells with gentle...
    DATE: March 18, 2021 TIME: 8:00am PDT Sequencing of bulk cells, single cells, and nuclei is opening doors in the understanding of complex biological processes....
    Speaker: Alexander Jonsson , Dr. Alina Steinbach
    Sponsored By: Miltenyi Biotec
    11
    FEB 24, 2021 | 12:00 PM
    Deep Mechanistic profiling of immune oncology drug combinations in cancer patients with CIVO intratumoral micro-dosing and NanoString's GeoMx® Digital Spatial Profiler
    Deep Mechanistic profiling of immune oncology drug combinations...
    With an introduction by Sarah Warren, the Senior Director of Translational Science, this webinar will open by providing a brief technology overview of NanoString Technologies. Dr. Warren wil...
    Speaker: Jason Frazier , Sarah Warren, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    Sponsored By: NanoString Technologies
    2
    DEC 03, 2020 | 10:30 AM
    The Immunology of COVID-19: A dynamic immune signature for prognosis and spatial transcriptomics of lung tissue
    The Immunology of COVID-19: A dynamic immune signature for prognosis...
    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has spread globally, causing a pandemic of respiratory illness designated coronavirus disease 20...
    Speaker: Arutha Kulasinghe, PhD , Miguel Muñoz-Ruiz, PhD
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    3
     
     
  • NOV 19, 2020 | 9:00 AM
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
    Speaker: Kok Hao Chen , Alan Mullan, PhD
    Sponsored By: Andor
    6 2
    NOV 16, 2020 | 8:00 AM
    Targeted single-cell RNA sequencing enables genome-scale CRISPR screens
    Targeted single-cell RNA sequencing enables genome-scale CRISPR...
    Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
    Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer
    Sponsored By: Illumina
    11
    November 13, 2020 6:00 PM PST | November 14, 2020 10:00 AM SGT
    Q&A Session (In the RoundTable Room)
    Q&A Session (In the RoundTable Room)
    Visit the RoundTable Room to participate in live Q&A with all the speakers!...
    Speaker: Charalambos C. Solomides, MD , Sara Eglitis, MS, QIHC , Faruk Erdem Kombak, MD , Srabani Bhaumik, PhD , Nelson Alexander, PhD
    Presented at: DISCOVERY Global User Symposium
    0
    November 13, 2020 5:00 PM PST | November 14, 2020 9:00 AM SGT
    Representative sampling to address tumor heterogeneity
    Representative sampling to address tumor heterogeneity
    Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
    Speaker: Nelson Alexander, PhD
    Presented at: DISCOVERY Global User Symposium
    2
    November 12, 2020 11:00 AM PST | 6:00 PM GMT
    Q&A Session (In the RoundTable Room)
    Q&A Session (In the RoundTable Room)
    Visit the RoundTable Room to participate in live Q&A with all the speakers!...
    Speaker: Charalambos C. Solomides, MD , Sara Eglitis, MS, QIHC , Faruk Erdem Kombak, MD , Srabani Bhaumik, PhD , Nelson Alexander, PhD
    Presented at: DISCOVERY Global User Symposium
    1
     
     
  • November 12, 2020 10:00 AM PST | 5:00 PM GMT
    Representative sampling to address tumor heterogeneity
    Representative sampling to address tumor heterogeneity
    Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
    Speaker: Nelson Alexander, PhD
    Presented at: DISCOVERY Global User Symposium
    2
    NOV 09, 2020 | 10:00 AM
    TARGETED PROFILING OF CRITICALLY ILL SARS-CoV-2 SUBJECTS: FROM TRANSCRIPTOME TO PROTEOME
    TARGETED PROFILING OF CRITICALLY ILL SARS-CoV-2 SUBJECTS: FROM...
    Date: November 9th, 2020 Time: 10:00am PDT SARS-CoV-2 continues to spread rapidly with critically ill patients admitted to the intensive care unit (ICU), where the mortality rate is reported...
    Speaker: Douglas Fraser
    Sponsored By: Thermo Fisher Scientific
    16 2
    OCT 29, 2020 | 6:00 AM
    Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
    Single-cell sequencing to investigate epigenetic mechanisms in...
    Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
    Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
    Sponsored By: Illumina, Dolomite Bio
    15
    OCT 08, 2020 | 12:00 AM
    Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
    Transcriptome analysis of breast cancer clinical specimens with...
    Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
    Speaker: Masahito Kawazu, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
    Elucidation of remdesivir cytotoxicity pathways through genome-wide...
    The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
    Speaker: Minja Velimirovic, MSc, PhD Candidate
    Presented at: CRISPR Virtual Event Series 2020
    1
     
     
  • SEP 23, 2020 | 12:00 AM
    Transcriptomic signature : a spatially resolved analysis of the nephron structures in chronic kidney disease
    Transcriptomic signature : a spatially resolved analysis of the...
    Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for...
    Speaker: Paolo Cravedi, MD, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    2
    SEP 23, 2020 | 12:00 AM
    Deep learning to integrate histology with spatial transcriptomics
    Deep learning to integrate histology with spatial transcriptomics
    I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
    Speaker: James Zou
    Presented at: Cell Biology Virtual Event Series 2020
    1
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    Presented at: Cell Biology Virtual Event Series 2020
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    SEP 23, 2020 | 12:00 AM
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