During translation, cells 'read' genetic information in the form of messenger RNA and use this as a blueprint to synthesize proteins. Translation occurs continuously in living cells and is executed by organelles called ribosomes.
Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
During this seminar I will present details of my path from Beckman Scholar to MD-PhD, advanced training as a neurologist, then a neurointensivist, and the interleaving of additional research...
I will tell brief stories of experiences that have shaped my career, generalize the lessons learned, and translate them to three actionable items: (1) be careful with your pronouns, (2) embr...
RNA mediates essential biological processes in all organisms. These functions include catalysis of crucial biochemical reactions such as peptidyl transfer during translation and transesterif...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
Cytokine storm is suspected of producing the overzealous immune response driving the severe cardiopulmonary complications that fuel high morbidity and mortality rates in certain COVID-19 inf...
The need for high-throughput laboratory testing to identify SARS-CoV-2 infected individuals has reached nearly unprecedented levels. This demand has also led to supply chain issues that have...
Most bladder cancer (BC) cases are non-muscle-invasive BC (NIBMC), which is rarely lethal. However, nearly one-fifth of NMIBC cases progress to muscle-invasive BC (MIBC), which shows a 5-yea...
Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
During this seminar I will present details of my path from Beckman Scholar to MD-PhD, advanced training as a neurologist, then a neurointensivist, and the interleaving of additional research...
I will tell brief stories of experiences that have shaped my career, generalize the lessons learned, and translate them to three actionable items: (1) be careful with your pronouns, (2) embr...
RNA mediates essential biological processes in all organisms. These functions include catalysis of crucial biochemical reactions such as peptidyl transfer during translation and transesterif...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
Cytokine storm is suspected of producing the overzealous immune response driving the severe cardiopulmonary complications that fuel high morbidity and mortality rates in certain COVID-19 inf...
The need for high-throughput laboratory testing to identify SARS-CoV-2 infected individuals has reached nearly unprecedented levels. This demand has also led to supply chain issues that have...
Most bladder cancer (BC) cases are non-muscle-invasive BC (NIBMC), which is rarely lethal. However, nearly one-fifth of NMIBC cases progress to muscle-invasive BC (MIBC), which shows a 5-yea...
Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
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