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    Water Sampling

    Water sampling refers to the what happens during water analysis. There are two main methods: discrete and composite samples. Discrete samples refer to a single sample collected in an individual container. A composite sample refers to a series of samples collected at a predetermined time.

    Webinars

    • MAR 24, 2021 | 12:00 AM
      Aligning In-House and Commercial Analytical Testing Workflows for Cannabis Producers and Processors
      Aligning In-House and Commercial Analytical Testing Workflows...
      Accurate and reliable analytical cannabinoid potency data is essential to operating a compliant, consistent, and profitable cannabis company. Third-party testing labs service this industry n...
      Speaker: Shawn Helmueller, M.Sc.
      Presented at: Cannabis Sciences Virtual Event Series 2021
      1
      DEC 14, 2020 | 10:00 AM
      Testing Vaccines final dose form to USP<787> Subvisible Particulate Matter
      Testing Vaccines final dose form to USP<787> Subvisible Particulate...
      DATE: December 14, 2020 TIME: 10:00am PST USP chapter <787>, Subvisible Particulate Matter in Therapeutic Protein Injections, became official August 1, 2014 and provides specific guida...
      Speaker: Tony Harrison
      Sponsored By: Beckman Coulter Life Sciences
      7
      AUG 12, 2020 | 10:00 AM
      GMP Cleanroom Routine Environmental Monitoring & 21CFR part 11 Data Integrity
      GMP Cleanroom Routine Environmental Monitoring & 21CFR part 11...
      DATE: August 12, 2020 TIME: 10:00am PT Routine Environmental Monitoring in GMP cleanrooms is a manual process and is usually complex, involving thousands of sample data points per month, man...
      Speaker: Tony Harrison
      Sponsored By: Beckman Coulter Life Sciences
      9
      JUL 08, 2020 | 11:00 PM
      Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
      Mass Spectrometry Past and Present - Emerging Technologies and...
      DATE: July 9, 2020 TIME: 2pm SGT, 3pm JST, 4pm AEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not until around 30 to 40...
      Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
      Sponsored By: Waters Corporation
      17
      JUN 29, 2020 | 9:00 AM
      Remote, autonomous molecular analytical laboratories at sea and on land
      Remote, autonomous molecular analytical laboratories at sea and...
      DATE: June 29, 2020 TIME: 9:00am PT In both marine and freshwater systems, unmanned robots that use molecular analytical methods are rapidly changing how we sample, detect and quantify organi...
      Speaker: Christina Preston
      Sponsored By: MicroGem
      18
      JUN 25, 2020 | 8:00 AM
      Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
      Mass Spectrometry Past and Present - Emerging Technologies and...
      DATE: June 25, 2020 TIME: 8:00am PDT, 11:00am EDT, 4:00pm BST, 5:00pm CEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not...
      Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
      Sponsored By: Waters Corporation
      34
      JUN 24, 2020 | 10:00 AM
      The Fundamentals of Freeze Drying: Advice from the experts on how to get started
      The Fundamentals of Freeze Drying: Advice from the experts on...
      DATE: June 24, 2020 TIME: 10:00am PT Does your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize your lyo...
      Speaker: Megan Zimerman, B.A. in Biology , Jenny Sprung
      Sponsored By: Labconco
      18 1
      JUN 09, 2020 | 9:00 AM
      Sensitivity, Selectivity, and Speed:  Solving Analytical Challenges in Endocrinology using LC-MS/MS for Clinical Research
      Sensitivity, Selectivity, and Speed: Solving Analytical Challenges...
      DATE: June 9, 2020 TIME: 9am SGT, 10am JST, 11am AEST The use of LC-MS/MS technologies in Endocrinology for clinical research is experiencing rapid growth....
      Speaker: Dominic Foley
      Sponsored By: Waters Corporation
      15 1
      MAY 26, 2020 | 8:00 AM
      Sensitivity, Selectivity, and Speed:  Solving Analytical Challenges in Endocrinology using LC-MS/MS for Clinical Research
      Sensitivity, Selectivity, and Speed: Solving Analytical Challenges...
      DATE: May 26, 2020 TIME: 8:00am PT, 11:00am ET, 4:00pm BST, 5:00pm CEST The use of LC-MS/MS technologies in Endocrinology for clinical research is an area of rapid growth. This is a result o...
      Speaker: Dominic Foley
      Sponsored By: Waters Corporation
      18 3
      APR 29, 2020 | 6:00 AM
      Direct Detection and Typing of Variety Pathogens Important for Human and Animal Health Using xMAP Technology
      Direct Detection and Typing of Variety Pathogens Important for...
      Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
      Speaker: Petr Kralik, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      2
      DEC 18, 2019 | 10:00 AM
      Understanding Your Biosafety Cabinet: 3 Approaches to Improving Safety in the Laboratory
      Understanding Your Biosafety Cabinet: 3 Approaches to Improving...
      DATE: December 18, 2019TIME: 10:00am PSTDavid is the Product Marketing Manager for Biosafety Cabinets at Labconco Corporation (Kansas City, MO). For several years, David has been involv...
      Speaker: David Wasescha
      Sponsored By: Labconco
      13 1
      NOV 14, 2019 | 6:00 AM
      High Resolution View of D4Z4 Repeat Regions for Studying Facioscapulohumeral Muscular Dystrophy (FSHD) Using Whole Genome Optical Mapping
      High Resolution View of D4Z4 Repeat Regions for Studying Facioscapulohumeral...
      Facioscapulohumeral muscular dystrophy (FSHD), one of the most common forms of progressive muscular dystrophies and is often conventionally diagnosed by Southern blot analysis. The accurate d...
      Speaker: Alka Chaubey, PhD, FACMG
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
      Sponsored By: Bionano
      2
      OCT 24, 2019 | 6:00 AM
      Multidimension Chromatography; a Disruptive Technology - A Netflix Effect in the World of Chromatography!
      Multidimension Chromatography; a Disruptive Technology - A Netflix...
      Chromatography is the first choice in separation technique for a wide selection of applications, across many fields, ranging from simple to highly complex extracts. The main rationale for it...
      Speaker: Claude Mallet, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      2
      OCT 16, 2019 | 10:00 AM
      Overcome Top Titration Challenges
      Overcome Top Titration Challenges
      DATE: October 16, 2019TIME: 9:00am PDTManual titrations can be extremely challenging and frustrating, impeding your efficiency in the lab. More importantly, these issues can lead to inc...
      Speaker: Ricki Hartwell , Gayle Gleichauf , Kevin Goohs
      Sponsored By: Thermo Fisher Scientific
      6 1
      OCT 10, 2019 | 12:00 PM
      Tumor Mutation Burden: Challenges and opportunities of measuring and interpreting tumor mutational burden for patient care
      Tumor Mutation Burden: Challenges and opportunities of measuring...
      Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
      Speaker: Ravindra Kolhe, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      OCT 02, 2019 | 11:00 AM
      Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS
      Ditch the Excel spreadsheets and manage your molecular workflows...
      DATE: October 2, 2019TIME: 11:00am PDT, 2:00pm EDT Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS Achieve configuration of molecular workf...
      Speaker: Karla Paulson, MBA, PMP, LSSGB
      Sponsored By: Abbott Informatics
      3 2
      JUN 12, 2019 | 9:00 AM
      Freeze Drying Solutions For Your Lab
      Freeze Drying Solutions For Your Lab
      DATE: June 12, 2019TIME: 9:00am PDTDoes your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize you...
      Speaker: Jenny Sprung , Megan Zimerman, B.A. in Biology
      Sponsored By: Labconco
      4
      MAR 28, 2019 | 9:00 AM
      Analysis of Cannabis for Pesticides and Mycotoxins Using UPLC-MS/MS and GC-MS/MS
      Analysis of Cannabis for Pesticides and Mycotoxins Using UPLC-MS/MS...
      Quantitative methods for residual pesticides and mycotoxins analysis in cannabis should provide reliable coverage and robust methodology for the entire list of analytes to fulfill the state m...
      Speaker: Marian Twohig, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      4
      JUL 18, 2018 | 9:00 AM
      Freeze Drying Solutions For Your Lab
      Freeze Drying Solutions For Your Lab
      Does your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize your lyophilization process. This webinar will...
      Speaker: Megan Zimerman, B.A. in Biology , Jenny Sprung
      Sponsored By: Labconco
      7
      MAR 28, 2018 | 10:30 AM
      Factors That Influence Label Accuracy - Who's to Blame?
      Factors That Influence Label Accuracy - Who's to Blame?
      DATE: March 28, 2018TIME: 10:30AM PDTAs consumers in modern society, we have become accustomed to the purchase of foods and drugs that are safe and accurately labeled. This is a result...
      Speaker: Catharine Layton
      Presented at: Cannabis Sciences Virtual Event Series 2018
      4
      MAR 28, 2018 | 9:00 AM
      Sampling for Cannabis Testing
      Sampling for Cannabis Testing
      Compliance testing is the key to getting your cannabis products to market.  But also ensuring your product safety and label accuracy require not only good laboratory analyses, but consis...
      Speaker: Shawn Kassner
      Presented at: Cannabis Sciences Virtual Event Series 2018
      3
      OCT 24, 2017 | 7:00 AM
      WEBINAR: Biomarker Discovery: Metabolomics Differentiates Known Disease Classifications of Prostate Cancer
      WEBINAR: Biomarker Discovery: Metabolomics Differentiates Known...
      DATE: October, 24, 2017TIME:  7:00 AM PDT Metabolomics focuses on the chemical processes central to cellular metabolism. A robust mass spectrometry solution for screening...
      Speaker: Timothy Garrett, PhD
      Sponsored By: SCIEX
      4 1
      JUL 27, 2017 | 9:00 AM
      WEBINAR: Advances in Laboratory Freeze Drying
      WEBINAR: Advances in Laboratory Freeze Drying
      DATE: July 27, 2017TIME: 9:00AM PT, 11:00AM CT, 12:00PM ETDo you have inconsistent results freeze drying samples? Are some of your samples too challenging? Is your freeze dry cycle taki...
      Speaker: Kelly Williams, BA Biology, MBA , Jenny Sprung
      Sponsored By: Labconco
      7
      NOV 08, 2016 | 10:00 AM
      The genetics of aquaculture: Genotyping with GBS and arrays for species identification and trait improvement
      The genetics of aquaculture: Genotyping with GBS and arrays for...
      DATE: November 8, 2016 TIME: 10:00am PT, 1:00pm ET Stock and individual identification of Coho and Chinook Salmon in British Columbia via amplicon sequencing We have assemble...
      Speaker: Terry Beacham, PhD , Yniv Palti, PhD
      Sponsored By: Affymetrix, part of Thermo Fisher Scientific, Affymetrix, part of Thermo Fisher Scientific
      5 1
    MAR 24, 2021 | 12:00 AM
    Aligning In-House and Commercial Analytical Testing Workflows for Cannabis Producers and Processors
    Aligning In-House and Commercial Analytical Testing Workflows...
    Accurate and reliable analytical cannabinoid potency data is essential to operating a compliant, consistent, and profitable cannabis company. Third-party testing labs service this industry n...
    Speaker: Shawn Helmueller, M.Sc.
    Presented at: Cannabis Sciences Virtual Event Series 2021
    1
    DEC 14, 2020 | 10:00 AM
    Testing Vaccines final dose form to USP<787> Subvisible Particulate Matter
    Testing Vaccines final dose form to USP<787> Subvisible Particulate...
    DATE: December 14, 2020 TIME: 10:00am PST USP chapter <787>, Subvisible Particulate Matter in Therapeutic Protein Injections, became official August 1, 2014 and provides specific guida...
    Speaker: Tony Harrison
    Sponsored By: Beckman Coulter Life Sciences
    7
    AUG 12, 2020 | 10:00 AM
    GMP Cleanroom Routine Environmental Monitoring & 21CFR part 11 Data Integrity
    GMP Cleanroom Routine Environmental Monitoring & 21CFR part 11...
    DATE: August 12, 2020 TIME: 10:00am PT Routine Environmental Monitoring in GMP cleanrooms is a manual process and is usually complex, involving thousands of sample data points per month, man...
    Speaker: Tony Harrison
    Sponsored By: Beckman Coulter Life Sciences
    9
    JUL 08, 2020 | 11:00 PM
    Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
    Mass Spectrometry Past and Present - Emerging Technologies and...
    DATE: July 9, 2020 TIME: 2pm SGT, 3pm JST, 4pm AEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not until around 30 to 40...
    Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
    Sponsored By: Waters Corporation
    17
    JUN 29, 2020 | 9:00 AM
    Remote, autonomous molecular analytical laboratories at sea and on land
    Remote, autonomous molecular analytical laboratories at sea and...
    DATE: June 29, 2020 TIME: 9:00am PT In both marine and freshwater systems, unmanned robots that use molecular analytical methods are rapidly changing how we sample, detect and quantify organi...
    Speaker: Christina Preston
    Sponsored By: MicroGem
    18
     
     
  • JUN 25, 2020 | 8:00 AM
    Mass Spectrometry Past and Present - Emerging Technologies and Strategies for Quality Management in Today's Clinical Laboratory
    Mass Spectrometry Past and Present - Emerging Technologies and...
    DATE: June 25, 2020 TIME: 8:00am PDT, 11:00am EDT, 4:00pm BST, 5:00pm CEST Mass Spectrometry (MS) has been an invaluable tool for physicists and basic chemists for over 100 years. It was not...
    Speaker: SM Hossein Sadrzadeh, PhD., DABCC, FAACC , Dennis Orton, PhD, FCACB , Jessica Boyd, PhD, FCACB
    Sponsored By: Waters Corporation
    34
    JUN 24, 2020 | 10:00 AM
    The Fundamentals of Freeze Drying: Advice from the experts on how to get started
    The Fundamentals of Freeze Drying: Advice from the experts on...
    DATE: June 24, 2020 TIME: 10:00am PT Does your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize your lyo...
    Speaker: Megan Zimerman, B.A. in Biology , Jenny Sprung
    Sponsored By: Labconco
    18 1
    JUN 09, 2020 | 9:00 AM
    Sensitivity, Selectivity, and Speed:  Solving Analytical Challenges in Endocrinology using LC-MS/MS for Clinical Research
    Sensitivity, Selectivity, and Speed: Solving Analytical Challenges...
    DATE: June 9, 2020 TIME: 9am SGT, 10am JST, 11am AEST The use of LC-MS/MS technologies in Endocrinology for clinical research is experiencing rapid growth....
    Speaker: Dominic Foley
    Sponsored By: Waters Corporation
    15 1
    MAY 26, 2020 | 8:00 AM
    Sensitivity, Selectivity, and Speed:  Solving Analytical Challenges in Endocrinology using LC-MS/MS for Clinical Research
    Sensitivity, Selectivity, and Speed: Solving Analytical Challenges...
    DATE: May 26, 2020 TIME: 8:00am PT, 11:00am ET, 4:00pm BST, 5:00pm CEST The use of LC-MS/MS technologies in Endocrinology for clinical research is an area of rapid growth. This is a result o...
    Speaker: Dominic Foley
    Sponsored By: Waters Corporation
    18 3
    APR 29, 2020 | 6:00 AM
    Direct Detection and Typing of Variety Pathogens Important for Human and Animal Health Using xMAP Technology
    Direct Detection and Typing of Variety Pathogens Important for...
    Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
    Speaker: Petr Kralik, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    2
     
     
  • DEC 18, 2019 | 10:00 AM
    Understanding Your Biosafety Cabinet: 3 Approaches to Improving Safety in the Laboratory
    Understanding Your Biosafety Cabinet: 3 Approaches to Improving...
    DATE: December 18, 2019TIME: 10:00am PSTDavid is the Product Marketing Manager for Biosafety Cabinets at Labconco Corporation (Kansas City, MO). For several years, David has been involv...
    Speaker: David Wasescha
    Sponsored By: Labconco
    13 1
    NOV 14, 2019 | 6:00 AM
    High Resolution View of D4Z4 Repeat Regions for Studying Facioscapulohumeral Muscular Dystrophy (FSHD) Using Whole Genome Optical Mapping
    High Resolution View of D4Z4 Repeat Regions for Studying Facioscapulohumeral...
    Facioscapulohumeral muscular dystrophy (FSHD), one of the most common forms of progressive muscular dystrophies and is often conventionally diagnosed by Southern blot analysis. The accurate d...
    Speaker: Alka Chaubey, PhD, FACMG
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2019
    Sponsored By: Bionano
    2
    OCT 24, 2019 | 6:00 AM
    Multidimension Chromatography; a Disruptive Technology - A Netflix Effect in the World of Chromatography!
    Multidimension Chromatography; a Disruptive Technology - A Netflix...
    Chromatography is the first choice in separation technique for a wide selection of applications, across many fields, ranging from simple to highly complex extracts. The main rationale for it...
    Speaker: Claude Mallet, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    2
    OCT 16, 2019 | 10:00 AM
    Overcome Top Titration Challenges
    Overcome Top Titration Challenges
    DATE: October 16, 2019TIME: 9:00am PDTManual titrations can be extremely challenging and frustrating, impeding your efficiency in the lab. More importantly, these issues can lead to inc...
    Speaker: Ricki Hartwell , Gayle Gleichauf , Kevin Goohs
    Sponsored By: Thermo Fisher Scientific
    6 1
    OCT 10, 2019 | 12:00 PM
    Tumor Mutation Burden: Challenges and opportunities of measuring and interpreting tumor mutational burden for patient care
    Tumor Mutation Burden: Challenges and opportunities of measuring...
    Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
    Speaker: Ravindra Kolhe, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
     
     
  • OCT 02, 2019 | 11:00 AM
    Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS
    Ditch the Excel spreadsheets and manage your molecular workflows...
    DATE: October 2, 2019TIME: 11:00am PDT, 2:00pm EDT Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS Achieve configuration of molecular workf...
    Speaker: Karla Paulson, MBA, PMP, LSSGB
    Sponsored By: Abbott Informatics
    3 2
    JUN 12, 2019 | 9:00 AM
    Freeze Drying Solutions For Your Lab
    Freeze Drying Solutions For Your Lab
    DATE: June 12, 2019TIME: 9:00am PDTDoes your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize you...
    Speaker: Jenny Sprung , Megan Zimerman, B.A. in Biology
    Sponsored By: Labconco
    4
    MAR 28, 2019 | 9:00 AM
    Analysis of Cannabis for Pesticides and Mycotoxins Using UPLC-MS/MS and GC-MS/MS
    Analysis of Cannabis for Pesticides and Mycotoxins Using UPLC-MS/MS...
    Quantitative methods for residual pesticides and mycotoxins analysis in cannabis should provide reliable coverage and robust methodology for the entire list of analytes to fulfill the state m...
    Speaker: Marian Twohig, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    4
    JUL 18, 2018 | 9:00 AM
    Freeze Drying Solutions For Your Lab
    Freeze Drying Solutions For Your Lab
    Does your work require you to freeze dry samples? Are your results inconsistent? Is your freeze dry cycle taking too long? Learn how to optimize your lyophilization process. This webinar will...
    Speaker: Megan Zimerman, B.A. in Biology , Jenny Sprung
    Sponsored By: Labconco
    7
    MAR 28, 2018 | 10:30 AM
    Factors That Influence Label Accuracy - Who's to Blame?
    Factors That Influence Label Accuracy - Who's to Blame?
    DATE: March 28, 2018TIME: 10:30AM PDTAs consumers in modern society, we have become accustomed to the purchase of foods and drugs that are safe and accurately labeled. This is a result...
    Speaker: Catharine Layton
    Presented at: Cannabis Sciences Virtual Event Series 2018
    4
     
     
  • MAR 28, 2018 | 9:00 AM
    Sampling for Cannabis Testing
    Sampling for Cannabis Testing
    Compliance testing is the key to getting your cannabis products to market.  But also ensuring your product safety and label accuracy require not only good laboratory analyses, but consis...
    Speaker: Shawn Kassner
    Presented at: Cannabis Sciences Virtual Event Series 2018
    3
    OCT 24, 2017 | 7:00 AM
    WEBINAR: Biomarker Discovery: Metabolomics Differentiates Known Disease Classifications of Prostate Cancer
    WEBINAR: Biomarker Discovery: Metabolomics Differentiates Known...
    DATE: October, 24, 2017TIME:  7:00 AM PDT Metabolomics focuses on the chemical processes central to cellular metabolism. A robust mass spectrometry solution for screening...
    Speaker: Timothy Garrett, PhD
    Sponsored By: SCIEX
    4 1
    JUL 27, 2017 | 9:00 AM
    WEBINAR: Advances in Laboratory Freeze Drying
    WEBINAR: Advances in Laboratory Freeze Drying
    DATE: July 27, 2017TIME: 9:00AM PT, 11:00AM CT, 12:00PM ETDo you have inconsistent results freeze drying samples? Are some of your samples too challenging? Is your freeze dry cycle taki...
    Speaker: Kelly Williams, BA Biology, MBA , Jenny Sprung
    Sponsored By: Labconco
    7
    NOV 08, 2016 | 10:00 AM
    The genetics of aquaculture: Genotyping with GBS and arrays for species identification and trait improvement
    The genetics of aquaculture: Genotyping with GBS and arrays for...
    DATE: November 8, 2016 TIME: 10:00am PT, 1:00pm ET Stock and individual identification of Coho and Chinook Salmon in British Columbia via amplicon sequencing We have assemble...
    Speaker: Terry Beacham, PhD , Yniv Palti, PhD
    Sponsored By: Affymetrix, part of Thermo Fisher Scientific, Affymetrix, part of Thermo Fisher Scientific
    5 1
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