SEP 13, 2018 7:30 AM PDT

Keynote Presentation: Tracking the Resistome in One Health Surveillance

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Director, The National Antimicrobial Resistance Monitoring System, Office of Research, Center for Veterinary Medicine, Food & Drug Administration
    Biography
      Dr. Patrick McDermott is Director of the National Antimicrobial Resistance Monitoring System (NARMS) at the Food & Drug Administration. NARMS was established in 1996 and is an interagency collaborative effort between the FDA, USDA and CDC that tracks antibiotic resistance in bacteria from retail meats, food producing animals and human clinical cases of infection. He led studies to develop the first standardized antimicrobial susceptibility testing methods for Campylobacter, conducted work to show the impact of antimicrobials in animals, and coordinated the implementation of whole genome sequencing into NARMS national surveillance. His collaborative work aims to understand the mechanisms of antimicrobial resistance in foodborne microorganisms, how they emerge and spread, and the impact of interventions designed to limit resistance in food animal production. He is a fellow of the American Academy of Microbiology, and recipient of the FDA's Francis Kelsey award for excellence and courage in protecting the public health.

    Abstract

    In the US, the National Antimicrobial Resistance Monitoring System has been using WGS of Salmonella as a tool of routine surveillance since 2013. To date, NARMS has generated MIC and WGS data on over 10,000 Salmonella isolates from food animals, 9,000 from human clinical cases, 6,000 from retail meats, and 1,4OO from imported foods. Analysis of this dataset showed that the presence of known resistance determinants is very highly correlated with clinical resistance, indicating that WGS data can be used to predict resistance in Salmonella strains lacking traditional antimicrobial susceptibility data. To make these data accessible, the NARMS program has launched Resistome Tracker and other online tools that provide visually informative displays of antibiotic resistance genes. Resistome Tracker harvests resistance gene information on a weekly basis from genomic data deposited at NCBI. It presents the resistome data using interactive dashboards that allows users to customize visualizations by antibiotic drug class, compare resistance genes across different sources, identify new resistance genes, and map selected resistance genes to geographic region. The tool also provides alerts about new resistance traits as they emerge in a region or source to provide early warning on emergent trends. 

    Learning Objectives: 

    1. The technical aspects of integrated antimicrobial resistance monitoring 
    2. The utility of whole genome sequence data in resistance surveillance
    3. Visualization and reporting tools to foster global data sharing


    Show Resources
    You May Also Like
    NOV 18, 2019 7:00 AM PST
    C.E. CREDITS
    NOV 18, 2019 7:00 AM PST
    DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
    APR 07, 2020 8:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    APR 07, 2020 8:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    OCT 02, 2019 11:00 AM PDT
    OCT 02, 2019 11:00 AM PDT
    DATE: October 2, 2019TIME: 11:00am PDT, 2:00pm EDT Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS Achieve configuration of molecular workf...
    JAN 23, 2020 9:00 AM PST
    C.E. CREDITS
    JAN 23, 2020 9:00 AM PST
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    MAY 12, 2020 10:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    MAY 12, 2020 10:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: May 12, 2020 TIME: 10:00am PT, 1:00pm ET The presentation will first discuss sepsis as a disease and then explain the importance of performing diagnostic tests in the clinical labora...
    FEB 26, 2020 9:00 AM PST
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    Loading Comments...
    Show Resources