SEP 12, 2018 10:30 AM PDT

Laboratory Role in Diagnosis of Antiphospholipid Antibodies and Antiphospholipid Syndrome

Speaker
  • Assistant Professor of Clinical Pathology, University of Illinois at Chicago
    Biography
      He is the director of Coagulation and director of Point-of-Care Testing at University of Illinois Hospital and Health Sciences System in Chicago, and Blood Bank/Transfusion Medicine attending physician in the same institution. From 2015-2017 he held the position of Interim Director of Clinical Pathology. He is also the Laboratory Medical Director at Shriners Hospital for Children in Chicago.

    Abstract

    The ongoing research and scientific debate on pathophysiology, classification, nomenclature and diagnosis of antiphospholipid syndrome illustrates the complexity of cellular membranes, their dynamic interplay with various components in circulating blood, and often tenuous balance between normal hemostasis and thrombosis. This main objective of this lecture is to succinctly identify the features of normal vs. pathological coagulation, and to familiarize the audience with the inextricable, and ever-evolving role of laboratory in diagnostic process of antiphospholipid syndrome.       
     

    Learning Objectives: 

    1. Understand the physiological role of phospholipids in normal hemostasis.
    2. Identify a few proposed pathophysiological mechanisms for thrombosis in the presence of antiphospholipid antibodies.
    3. Be familiar with the current diagnostic criteria for antiphospholipid syndrome ( APS).
    4. Laboratory detection of antiphospholipid antibodies and future directions.


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