MAR 19, 2015 10:30 AM PDT

Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor Systems: 3 Decades of Progress

Speaker
  • Radiology Vice Chair for Research Administration and Training, Professor of Radiology and Radiological Science, Johns Hopkins University School of Medicine
    BIOGRAPHY

Abstract

Since the discovery and maturing of in vitro techniques that characterized neurotransmitter receptor systems in animal and human brain and subsequent development of in vitro and in vivo autoradiography, there was always a clear scientific motivation to carry out these measurements in living brain. In the early 1980s, this was realized by both in vivo preclinical and ultimately human imaging of neurotransmitter (NT) systems starting with dopamine opiate and serotonin system. Now, some 30 years later, the in vivo imaging of (NT) receptor systems, primarily employing the methodology known as positron emission tomography (PET), single photon imaging computer tomography (SPECT) and other chemical measures including magnetic resonance spectroscopy (MRS) and pfMRI (pharmacologic magnetic resonance imaging) have dramatically established these approaches as valuable tools for neuroscience research.


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MAR 19, 2015 10:30 AM PDT

Special Lecturer - In Vivo PET /SPECT Imaging of Human Brain Neuroreceptor Systems: 3 Decades of Progress



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