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Point-of-care testing (POCT) is destined to play a much greater role in chronic disease diagnosis and management. Advanced POCT systems are being developed to deliver less costly and more ac...
Immunotherapy: An unprecedented opportunity-Long-lasting/curative treatments-Lower side effects-Wide applicability-Natural mechanism of action-Locally produced T cell therapies&...
A panel of experts will discuss recent advances and current challenges for the successful development and application of human tissue for drug screening, tissue replacement and eventually org...
The GeneStrat® Genomic Test is a blood-based series of ddPCR tests for DNA (EGFR, KRAS, BRAF) and multiplexed assays for RNA variants (EML4-ALK, ROS1, RET). In this report we will u...
Single cell RNA sequencing (scRNA-seq) emerged to characterize gene expression differences between individual cells, allowing a higher resolution look at mRNA abundance than bulk RNA- seq. H...
Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
With technology advances and collaboration between engineers and neuroscientists, single-synapse network maps of the brain are possible at increasing scales. In this symposium, our speakers...
What motivates patients to participate in clinical trials? Discussions most often revolve around potential study participants’ perception of therapeutic benefit. Misconceptions about th...
immunocompromised populations where the virus can cause systemic and even fatal infections. Indeed, we have shown that astrovirus infections are more prevalent than norovirus in our pediatric...
RNA-Seq has been used for the past decade to gain significant insights into gene expression. Using bulk methods however only allow for an understanding of the average gene expression within a...
Autism spectrum disorder (ASD) is a complex group of individually rare neurological conditions with genetic and non-genetic causes. Despite the strong genetic component of ASD, it has been ve...
Research on human brain development and neurological diseases is limited by the lack of advanced experimental in vitro models that truly recapitulate the complexity of the human brain. Here, ...
Respiratory tract infections (RTIs) are a significant public health concern due to their widespread transmission and high rates of illness and death globally. Syndromic molecular methods hav...
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
This presentation describes the new process by which the Centers for Medicare and Medicaid Services (CMS) will establish the prices the Agency pays for clinical diagnostic laboratory tests.&n...
A hypoxic tumour microenvironment is a feature of solid tumours. Many tumour types contain high fractions of hypoxic tissue. The relationship between high levels of tumour hypoxia and a poor...
Vaginal microbial communities play an important role in women’s heath. It is now clear that the vaginal microbiome is linked to pregnancy complications such as preterm birth and risk f...
A collection of opinions, questions and other assorted thoughts about the intersection of these developing technologies and preclinical studies primarily focused on the early discovery (as op...
With annual sales exceeding $145 billion, growth of biologic therapeutics is outpacing that of small-molecule drugs, and the development, manufacture, and delivery of biologics presents very...
Drug development is a costly and time consuming process, poor translation of data from pre-clinical studies to the clinic is a major contributor as late-stage drug failure is very expensive....
In 1910, Harrison published the first report of frog embryonic sympathetic ganglia grown in hanging drops of lymph for a few days, where single neurons extended nerve fibers with complex gro...
Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
Review the similarities and differences between apoptosis and necroptosis, with an introduction to new tools developed to activate effectors of necroptosis....
In today’s modern laboratory, resources are often stretched as laboratories struggle to manage multiple priorities, meet regulatory requirements, and contain costs. This is especially t...
A rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...
New insights on the pathogenesis of COVID-19 7:00–7:30 pm PDT Presented By: Olaf Rötzschke, PhD The SIgN Mass Cytometry Platform (MCP) was originally established by Evan Newell, P...
Point-of-care testing (POCT) is destined to play a much greater role in chronic disease diagnosis and management. Advanced POCT systems are being developed to deliver less costly and more ac...
