Browse our archive of webinars on pharmaceutical and biomedical research from collaborations between pharmaceutical companies, government, biotechnology companies and academia to create new drug discovery opportunities.
In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
Specific biomarker assays are included in an increasing number of drug labels, with uses ranging from prediction of adverse events to providing insights on efficacy for patient populations....
High throughput purification is a critical step for antibody engineering and screening. Protein purification using traditional protein A resin columns is limited by throughput and a complica...
What does a quantum leap in drug development look like and what is necessary to make it happen? Our greatest opportunity to deliver significant increases in the speed and effectiveness of dr...
The prevalence of NASH in global populations continues to expand in conjunction with the ongoing obesity and diabetes epidemic. Over the next decade, the disease is projected to become the l...
Multiplexing IHC is a technique that is increasing in demand as more and more researchers and physicians are being tasked with doing more with less. With multiplexing, you have the advantage...
Reliable diagnostic, prognostic, predictive, pharmacodynamic, and pharmacokinetic biomarkers are critical to assure correct patient selection, drug dosing, and monitoring. Being able to iden...
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
This lecture introduces the evolving paradigm of Molecular Pathological Epidemiology (MPE) as simply as possible. Any given human disease represents fundamentally heterogeneous process,...
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
In the last years a number of advanced nanotechnologies have been proposed developed for the administration of drugs (nanomedicines for drug delivery), in order to provide possibilities...
If you use a pipette on a daily basis, then this webinar is for you. Pipettes are used to prepare samples, blanks, and standards for a range of analytical experiments. This is why the wrong...
G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...
The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
Learning Objectives: 1. Describe the exposure response relationships with vancomycin and acute kidney injury 2. Define biomarkers that may be useful to improve Precision Dosing...
Adhesion G protein-coupled receptors (aGPCRs) are an ancient class of receptors that represent some of the largest transmembrane-integrated proteins in humans. Besides classic features of GP...
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease affecting approximately 1 in 50,000 people worldwide. About 10% of these cases are found to have a hereditary component, bu...
Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
With an introduction by Sarah Warren, the Senior Director of Translational Science, this webinar will open by providing a brief technology overview of NanoString Technologies. Dr. Warren wil...
Small size, highly selective nature, flexible chemistry and ease of manufacturing make nucleic acid aptamers attractive for multiple applications in human diagnostics and drug discovery. &nbs...
Single-cell gene expression analysis helps biologists and bioinformaticians reveal complex and rare cell populations, uncover regulatory relationships among genes and analyze and visualize g...
Have you ever tried to access the genomic profiles of cell lines before using them in your preclinical experiments just to come up empty-handed? Maybe you’ve scoured public databases f...
Princess Margaret Living Biobank (PMLB) is a repository for patient-derived organoid models. PMLB has generated over200 organoid models from lung, pancreas, colon, ovary, esophageal and brea...
In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
![Anti-PRAME antibody [EPR20330]](https://d3bkbkx82g74b8.cloudfront.net/eyJidWNrZXQiOiJsYWJyb290cy1pbWFnZXMiLCJrZXkiOiJjb21wYW55X3Byb2R1Y3RfcHJvZmlsZV9pbWFnZV9mMzEwNTY4MGY1NmVmZjU3ZjZhMWRkZTU2M2Q4YjBmODZjMDJkNDE4XzMwMDA3MTg1ODEyLmpwZyIsImVkaXRzIjp7InRvRm9ybWF0IjoianBnIiwicmVzaXplIjp7IndpZHRoIjozMDAsImhlaWdodCI6MzAwLCJmaXQiOiJjb3ZlciIsInBvc2l0aW9uIjoiY2VudGVyIiwiYmFja2dyb3VuZCI6IiNmZmYifSwiZmxhdHRlbiI6eyJiYWNrZ3JvdW5kIjoiI2ZmZiJ9fX0=)
